Clinical trials: sponsored by Asan Medical Center
Tuberculosis Infection
Development of Automated Molecular Diagnostic Platform for Tuberculosis Diagnosis (New Assay TB)
It is intended for patients who have been admitted to the outpatient or emergency room or are hospitalized For patients who diagnose pulmonary tuberculosis or extrapulmonary tuberculosis using Xpert TB/RIF, additionally, diagnose…
- Trial name
- New Assay TB (NCT04988984)
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Asan Medical Center
Thyroid, Cancer
Redifferentiation Therapy Using Alpha Lipoic Acid in Thyroid Cancer
Radioiodine (I-131) therapy is of proven efficacy for treatment of differentiated thyroid carcinoma (DTC). However, loss of differentiation in recurrent or metastatic DTC which decrease I-131 uptake may decrease the efficacy of…
- Trial name
- RALT (NCT01396733)
- Testing
- alpha-lipoic acids
- Where
- South Korea
- Sponsor
- Asan Medical Center
Coronary Artery Stenosis
FFR and Inducible Myocardial Ischemia During Adenosine Stress Testing
This is a prospective, single center study involving 150 patients with stable coronary artery disease undergoing coronary angiography for chest pain evaluation.
- Trial name
- NCT04401657
- Testing
- Fractional flow reserve with adenosine stress testing
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Asan Medical Center
Liver Transplantation and Antithrombin
Antithrombin III and Post-liver Transplantation Acute Kidney Injury
The reno-protective effect of Antithrombin III (ATIII) has been well-studied in various animal studies; however, little is known about the effect of ATIII on kidney function in patients undergoing liver transplantation (LT).
- Trial name
- NCT04912193
- Testing
- Antithrombin III
- Where
- South Korea
- Volunteers
- 2,395 people
- Sponsor
- Asan Medical Center
NSCLC
TAGRISSO (Osimertinib) in NSCLC Patients in Whom T790 Mutations Are Detected by Liquid Biopsy
In this trial, anti-tumor efficacy of TAGRISSO in NSCLC patients in whom T790 mutations are detected by liquid biopsy.
- Trial name
- NCT03394118
- Testing
- Osimertinib
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Asan Medical Center
Severe Acute Respiratory Syndrome Coronavirus 2, Coronavirus Infection
Fluvoxamine for Adults With Mild to Moderate COVID-19
This clinical trial aims to determine if fluvoxamine, a selective serotonin reuptake inhibitor with high affinity for the sigma-1 receptor, can be used in mild to moderate COVID-19 to prevent the progression to severe COVID-19.
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2, Coronavirus Infection, Mild to Moderate COVID-19
- Trial name
- NCT04711863
- Testing
- Fluvoxamine
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Asan Medical Center
Kidney Cancer
Effect of Papaverine on Renal Artery Blood Flow Volume
The purpose of this study is to evaluate the effect of papaverine on renal artery blood flow after declamping of renal artery.
- Trial name
- NCT04162834
- Testing
- Papaverine, Normal saline
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Asan Medical Center
Prostate Cancer
Detection of Clinically Significant Prostate Cancer Using a Urinary Multimarker Sensor
This trial aims to develop and validate the urinary multimarker sensor which can measure trace amounts of biomarkers from naturally voided urine in men referred with clinical suspicion of prostate cancer who have had no prior…
- Trial name
- NCT04825002
- Testing
- Urinary multimarker sensor
- Where
- South Korea
- Volunteers
- 800 people
- Sponsor
- Asan Medical Center
BPH
The Long Term Effects of Alfuzosin(Xatral XL) in Lower Urinary Tract Symptoms(LUTS)/BPH Patients
Benign prostatic hyperplasia (BPH) is a common condition among older men. The efficacy of α1-blockers for treating BPH has been well documented and they are recommended for the treatment of BPH by clinical guidelines.
- Trial name
- NCT00696761
- Testing
- Alfuzosin
- Volunteers
- 232 people
- Sponsor
- Asan Medical Center
Rectal Cancer
Preoperative CRT With Temozolomide Plus Capecitabine in Rectal Cancer
The investigators planned a phase I study of preoperative CRT with capecitabine plus temozolomide inpatients with locally advanced resectable rectal cancer: 1) the role of temozolomide as a radiosensitizer has been well…
- Trial name
- NCT01781403
- Testing
- Temozolomide
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Asan Medical Center
Tricuspid Regurgitation
Prospective Registry of Patients With Isolated Severe Tricuspid Regurgitation
Prospective registry for patients with severe isolated tricuspid regurgitation (TR) without significant left-sided valvular or myocardial diseases.
- Trial name
- NCT01502462
- Where
- South Korea
- Volunteers
- 131 people
- Sponsor
- Asan Medical Center
Tuberculosis
Development of Molecular Diagnostic Platform for Tuberculosis
This study evaluates new technique for diagnosis of tuberculosis. Among patients who are suspected with tuberculosis, participants will be tested conventional method including Xpert TB/RIF assay, and new diagnostic technique…
- Trial name
- NCT04734236
- Testing
- New technique vs Xpert
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Prostate Cancer
Internal Carotid Artery Blood Flow in Robot-Assisted Laparoscopic Prostatectomy
The purpose of this study is to evaluate the change of the internal carotid artery blood flow according to the steep trendelenburg position and pneumoperitoneum in patients undergoing robot-assisted laparoscopic prostatectomy.
- Trial name
- NCT04615494
- Testing
- Position
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Asan Medical Center
Advanced Colorectal Cancer
Efficacy Analysis of Cetuximab Plus Irinotecan in Patients With Wild-type KRAS Without Regard to Epidermal Growth Factor Receptor (EGFR) Expressions
The purpose of this study is to investigate the response rate of cetuximab plus irinotecan every 2 weeks in patients harboring wild-type KRAS with and without detectable EGFR-expressing metastatic CRC after failure to irinotecan…
- Trial name
- NCT00637091
- Testing
- Cetuximab, irinotecan
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Prostate Cancer, Biochemical Recurrence
Salvage Hypofractionated Accelerated Versus Standard Radiotherapy for Biochemical Failure After Prostatectomy
Patients with a biochemical recurrence after radical prostatectomy for moderate- or high- risk prostate cancer are randomly assigned to hypofractionated, accelerated high dose radiation therapy group (65 Gy, 26 fractions) and a…
- Conditions
- Prostate Cancer, Biochemical Recurrence, Radiation, Hypofractionation
- Trial name
- SHARE (NCT03920033)
- Testing
- Salvage radiation therapy
- Where
- 2 sites in South Korea
- Volunteers
- 288 people
- Sponsor
- Asan Medical Center
Renal Cell Cancer
Cabozantinib as Subsequent Therapy to an Immune Checkpoint Based Therapy in Renal Cell Carcinoma
This study is a phase 2, multicenter, interventional for cohort 1 \& 2, non-interventional for cohort 3, open-label trial of cabozantinib, with ORR as the primary efficacy endpoint.
- Trial name
- NCT04714697
- Testing
- Cabometyx
- Where
- South Korea
- Volunteers
- 201 people
- Sponsor
- Asan Medical Center
Radiotherapy, Toxicity
Prevention of Radiotherapy Induced Enteropathy by Probiotics (PREP)
In recent studies, a radiation-induced enteropathy is being reported over 50%. In clinics, probiotics are actively prescribed as a treatment for radiation-induced enteropathy.
- Conditions
- Radiotherapy, Toxicity, Diarrhea, Probiotics
- Trial name
- NCT03978949
- Testing
- Bacillus Licheniformis
- Where
- South Korea
- Volunteers
- 248 people
- Sponsor
- Asan Medical Center
Atrial Fibrillation, Valve Heart Disease
Dabigatran Versus Conventional Treatment for Prevention of Silent Cerebral Infarct in Atrial Fibrillation Associated With Valvular Disease
The prevalence of AF, which is tachyarrhythmia, is approximately 2% of the entire population and 5% of the population at the age of 60 or older.
- Trial name
- DECISIVE (NCT02982850)
- Testing
- Dabigatran, Acetylsalicylic acid, Warfarin
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Asan Medical Center
Hypertension
Effect of Rosuvastatin on Coronary Flow Reserve in Hypertensive Patients With Cardiovascular Risk
Investigators recently demonstrated that coronary flow reserve (CFR) significantly improved after rosuvastatin therapy in hypertensive patients with average levels of serum cholesterol by measuring the change in CFR after 1 year…
- Trial name
- RESERVE II (NCT02482207)
- Testing
- Rosuvastatin, Life style modification
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Asan Medical Center
Breast Cancer, Mobile Community
Distress Reduction by Activity Tracking and Activity Enhancement by Mobile Support Group in Oncology
This study aims to investigate the effect of the formation of social networks using smartphones can help increase physical activity and reduce stress in survivors after breast cancer treatment surgery.
- Trial name
- DRAAGON (NCT03783481)
- Testing
- Mobile community, No Mobile community
- Where
- South Korea
- Volunteers
- 202 people
- Sponsor
- Asan Medical Center