Clinical trials: sponsored by Asan Medical Center
Chronic Obstructive Pulmonary Disease
The Study for the Reliability and Validity of Incremental Shuttle Walking Test for COPD Patients in Korea
Investigators will perform this study to validate shuttle walking tests in korean patients with chronic obstructive pulmonary disease.
- Trial name
- NCT04178278
- Testing
- Shuttle walking test, Exercise stress test, 6 minutes walking test
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Pancreatic Adenocarcinoma
Neoadjuvant Modified FOLFIRINOX in Borderline Resectable Pancreatic Cancer
The purpose of this study is to assess the feasibility and efficacy outcomes of neoadjuvant modified FOLFIRINOX and postoperative gemcitabine in patients with borderline resectable pancreatic cancer.
- Trial name
- NCT02749136
- Testing
- Preoperative modified FOLFIRINOX and postoperative gemcitabine
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Asan Medical Center
Herpes Zoster, Postherpetic Neuralgia
The Superiority of Contralateral Oblique View for Mid-thoracic Epidural Assess
The aim of the present study is to compare contralateral oblique view with the lateral view for fluoroscopic guided mid-thoracic epidural assess.
- Conditions
- Herpes Zoster, Postherpetic Neuralgia, Cancer
- Trial name
- NCT03789955
- Testing
- Fluoroscopic-guided TEB
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Neuromuscular Blockade
Effectiveness of Deep Versus Moderate Neuromuscular Blockade
The aim of this study is to evaluate the influence of depth of neuromuscular blockade during laparoscopic gastrectomy on postoperative pain in surgical patients allocated randomly to either deep or moderate neuromuscular blockade…
- Trial name
- NCT03266419
- Testing
- Deep NMB using rocuronium, Moderate NMB using rocuronium
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Liver Transplant Disorder
Effect of 25-OH-vitamin D3 on the Liver Transplant Recipients
The low vitamin D3 levels and malnutrition before liver transplantation showed an increase in the length of stay in ICU and hospital.
- Trial name
- NCT04111146
- Where
- South Korea
- Volunteers
- 219 people
- Sponsor
- Asan Medical Center
Renal Fibrosis, Kidney Transplant Failure
Multicenter, Prospective Study for Urinary Exosomal Biomarkers of Kidney Allograft Tubulointerstitial Fibrosis
The investigators aim to identify urinary exosomal biomarkers that represent the extent of graft fibrosis from deceased donor kidney transplantation.
- Trial name
- UFO (NCT03870542)
- Testing
- kidney transplantation
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Tissue Donors, Liver Transplantation
The Effect of Remote Ischemic Preconditioning in Living Donor Hepatectomy
Liver transplantation is the gold standard treatment for patients with end-stage liver disease. Despite its outstanding success, liver transplantation still entails certain complications including ischemia-reperfusion injury.
- Conditions
- Tissue Donors, Liver Transplantation, Ischemia Reperfusion Injury
- Trial name
- NCT03386435
- Testing
- remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Asan Medical Center
Delirium
Environmental Intervention on Delirious Patients
The implementation of environmental intervention program reduced the duration of delirium and length of stay at the ICU in critically-ill surgical patients.
- Trial name
- NCT04042649
- Testing
- environmental intervention
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Asan Medical Center
Bacteremia
Epidemiologic Patterns of Bacteremia After Trauma
Presence of pelvic and liver injury on arrival in ED, gastrointestinal tract perforation and massive transfusion within the first 24 hours after trauma appear a significant risk factor for bacteremia.
- Trial name
- NCT04042636
- Where
- South Korea
- Volunteers
- 859 people
- Sponsor
- Asan Medical Center
Organ Preservation
Functional Organ Preservation Surgery
This is a prospective randomized controlled trial comparing functional organ preservation surgery (FOPS) vs. radiotherapy or chemoradiotherapy as the first treatment modality for patients with head an neck squamous cell carcinoma…
- Trial name
- FOPS (NCT01330056)
- Testing
- FOPS, CRT
- Where
- South Korea
- Volunteers
- 264 people
- Sponsor
- Asan Medical Center
Acute Myelogenous Leukemia
Randomized Study of Haploidentical Hct and Subsequent Donor nk Cell Infusion in High-risk AML and MDS
This is a single center, open label, random comparison phase 2b study. The primary objective of this study is, by random comparison, to assess the anti-leukemia effect of allogeneic, donor-derived natural killer (NK) cells…
- Trial name
- DNKI-4 (NCT02477787)
- Testing
- allogeneic, donor-derived NK cells
- Where
- South Korea
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Acute Myeloid Leukemia
Allogeneic HCT Using Uniform Conditioning Regimen Regardless of Donors (MS, MU, or HF) for AML in Remission
The purpose of this study is to evaluate the effect of various clinical variables including HLA-disparity and NK cell-related variables, upon outcomes of allogeneic hematopoietic cell transplantation (HCT) using uniform…
- Trial name
- AML_AlloHCT (NCT03337568)
- Testing
- allogeneic hematopoietic cell transplantation
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Extension Study of IDEAL (Imatinib) for Chronic Myelgenous Leukemia (CML)
This study is an extension study (prospective observational study) of 'IDEAL' study (A Study to Evaluate Efficacy and Safety of Imatinib (Glinib) 600mg/day depending on Early Molecular Response in Newly Diagnosed Patients with…
- Trial name
- IDEAL-E (NCT02421926)
- Testing
- IDEAL-E observation (investigators choice of imatinib, nilotinib, dasatinib, radotinib)
- Where
- 12 sites in South Korea
- Sponsor
- Asan Medical Center
Non-small Cell Lung Cancer
Haploidentical NK Cells After Pemetrexed in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)
This phase 1 trial investigate safety and maximum tolerated dose of natural killer (NK) cells derived from haploidentical family donors in patients with non-small cell lung cancer
- Trial name
- Medi-NK (NCT03366064)
- Testing
- Pemetrexed and donor-derived NK cell infusion
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Asan Medical Center
Attention Deficit Disorder With Hyperactivity
Identification of Neuropsychological, Genetic and Neuroimaging Markers and Treatment Response Predictors of ADHD
The objective of this study is to identification of neuropsychological, genetic and neuroimaging markers and treatment response predictors of attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT02430896
- Testing
- Methylphenidate (MPH), Atomoxetine
- Where
- South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Interstitial Cystitis
The Efficacy of Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome
The purpose of this study is to evaluate efficacy of biomarker in patient with interstitial cystitis/painful bladder syndrome
- Trial name
- NCT01985880
- Where
- 2 sites in South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Visceral Pain, Postoperative
The Visceral Analgesic Effect of Erector Spinae Plane Block in Laparoscopic Cholecystectomy
The purpose of this study was to investigate the effectiveness of erector spinae plane block on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
- Trial name
- NCT03767816
- Testing
- Ultrasound guided Rectus sheath block, Ultrasound erector spinae plane block
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Interstitial Cystitis
Observational Study of Hunner's Ulcer in Patient With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to observe change of distribution pattern of Hunner's ulcer in patient with interstitial cystitis/bladder pain syndrome
- Trial name
- NCT02150811
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Chronic Interstitial Cystitis
The Efficacy of Urine Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome (Pilot Study)
This study is to evaluate the efficacy of urine biomarker in patients with interstitial cystitis/painful bladder syndrome
- Trial name
- NCT02331472
- Where
- 2 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Depression, Suicidal Ideation
Identification of Genetic Markers and Predictors of Antidepressant-induced Suicidality in Youth Depression
The objective of this study is to identification of genetic markers and predictors of antidepressant-induced suicidality in youth depression.
- Trial name
- NCT02428439
- Testing
- bupropion or lamotrigine
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Asan Medical Center