Clinical trials: sponsored by Asan Medical Center
Hypertension, Pulmonary, Diseases of Mitral Valve
Effect of Sildenafil for Sustained PAH After MV Surgery (SUPERIOR Trial)
The purpose of this study is to determine whether Sildenafil is effective in the treatment of sustained pulmonary artery hypertension after corrected mitral valve disease.
- Trial name
- SUPERIOR (NCT02435303)
- Testing
- Sildenafil
- Volunteers
- 2 people
- Sponsor
- Asan Medical Center
Interstitial Cystitis
The Efficacy of Additional Intravesical Instillation of Hyaluronic Acid/Chondroitin Sulfate to Transurethral Resection of Bladder Ulcer in Patients With Interstitial Cystitis/Bladder Pain Syndrome.
The purpose of this study is to evaluate efficacy and safety of additional hyaluronic acid/chondroitin sulfate to transurethral resection of bladder ulcer in patient with interstitial cystitis.
- Trial name
- NCT01813565
- Testing
- Hyaluronic acid/chondroitin sulfate
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Asan Medical Center
Neoplasm, Prostate
Androgen Deprivation Therapy, External Beam Radiotherapy and Stereotactic Radiosurgery Boost for Prostate Cancer
For the treatment for intermediate- and high-risk prostate cancer, Cyberknife boost will be used after 4 weeks of intensity modulated radiotherapy to pelvis. The boost doses are 18 Gy and 21 Gy in 3 fractions, respectively.
- Trial name
- ADEBAR (NCT03322020)
- Testing
- Cyberknife boost 18 Gy, Cyberknife boost 21 Gy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Kidney Transplant; Complications, Aneurysm, Brain
Evaluation of Nephrectomy Specimen for Intracranial Aneurysm Development in ADPKD
ADPKD is the most common form of hereditary kidney disease and is known to occur in 1 of 400 to 1000 population in the U.S. ADPKD consists of 2.8% of patients receiving kidney transplantation in the investigator's center.
- Conditions
- Kidney Transplant; Complications, Aneurysm, Brain, Polycystic Kidney Diseases
- Trial name
- NCT03889392
- Testing
- Kidney transplantation and nephrectomy
- Volunteers
- 154 people
- Sponsor
- Asan Medical Center
Kidney Transplant; Complications, Polycystic Kidney Diseases
Evaluation of Iliac and Renal Artery for Mechanism of Intracranial Aneurysm in ADPKD
ADPKD is the most common form of hereditary kidney disease and is known to occur in 1 of 400 to 1000 population in the U.S. ADPKD consists of 2.8% of patients receiving kidney transplantation in our center.
- Conditions
- Kidney Transplant; Complications, Polycystic Kidney Diseases, Aneurysm, Brain
- Trial name
- NCT03726463
- Testing
- Kidney transplantation
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Pleural Effusion, Malignant, Non-small Cell Carcinoma
Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer
In this trial, the effect of intrapleural docetaxel administration using medical pleuroscopywill be evaluated in Lung Cancer patient with malignant effusion.
- Trial name
- NCT03394105
- Testing
- intrapleural docetaxel administration
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Asan Medical Center
Patient Monitoring
Patient Transfer Monitoring System in Hospital Using Mobile IoT Technology
This trial is multi-center prospective study to develop Patient Transfer Monitoring system using mobile lot network and the Risk Factor Detection System and apply to real In-Hospital Patients and verify the efficacy.
- Trial name
- NCT03574272
- Testing
- Patient Transfer Monitoring System
- Where
- 5 sites in South Korea
- Volunteers
- 143 people
- Sponsor
- Asan Medical Center
Cirrhosis of Liver
Gadoxetic Acid-MRI Versus Ultrasonography for the Surveillance of Hepatocellular Carcinoma in High-risk Patients
Current practice guidelines recommend surveillance for hepatocellular carcinoma (HCC) in liver cirrhosis patients with ultrasonography (USG) every 6 months.
- Trial name
- PRIUS (NCT01446666)
- Where
- South Korea
- Volunteers
- 423 people
- Sponsor
- Asan Medical Center
Stage IV Colorectal Cancer, Gastric Cancer
Investigation of Association Between UGT1A1 Polymorphisms and Irinotecan Toxicity in Korean Patients
The purpose of this study is to investigate the association between UGT1A1 polymorphisms and neutropenia and diarrhea in Korean patients with advanced colorectal or gastric cancer treated with FOLFIRI regimen.
- Trial name
- NCT01271582
- Testing
- Irinotecan, 5FU, leucovorin
- Where
- 5 sites in South Korea
- Volunteers
- 1,500 people
- Sponsor
- Asan Medical Center
Preemptive Peripheral Nerve Block, Pain, Postoperative
Preemptive Analgesic Effects of Rectus Sheath Block in Laparoscopic Cholecystectomy Patients
The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
- Conditions
- Preemptive Peripheral Nerve Block, Pain, Postoperative, Acute Pain
- Trial name
- NCT03413280
- Testing
- Ultrasound guided Rectus sheath block, Intercostal nerve block
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Stroke, Visual Field Defect
Visual Perceptual Learning for the Treatment of Visual Field Defect
This study will test the hypothesis whether visual field defect caused by chronic stroke could be improved by visual perceptual learning.
- Trial name
- VIVID (NCT01959256)
- Testing
- Visual perceptual learning
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Asan Medical Center
Ischemic Stroke
Certainty Of Stroke Symptom Onset Study
Intravenous tissue plasminogen activator (IV t-PA) is the only proven treatment of hyperacute cerebral infarction. The outcome of this treatment highly depends on the time from symptom onset to the administration of thrombolytic…
- Trial name
- COSSO (NCT01928641)
- Where
- South Korea
- Sponsor
- Asan Medical Center
Breast Cancer, Physical Activity
Development of Exercise Promotion Program Using a Mobile Community
This study aims to investigate the effect of a mobile community based on a smart phone application to enhance physical activities of breast cancer survivors.
- Trial name
- NCT03190720
- Testing
- Mobile community
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Asan Medical Center
Vestibular Neuritis
The Efficacy of Steroid Therapy in Vestibular Neuritis
The purpose of this study was to compare the treatment effectiveness of steroid therapy for vestibular neuritis by using video head impulse test.
- Trial name
- NCT02098330
- Testing
- Ginkgo biloba & Methylprednisolone, Ginkgo biloba
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Breast Cancer, Quality of Life
Development of Distress Management Algorithms Using Mobile Device Based Health Logs in Breast Cancer Survivors
Distress monitoring is an important issue in cancer survivors. However, conventional distress screening is very difficult to perform.
- Trial name
- NCT03072966
- Testing
- Wearable device (Fitbit Charge HR® or Fitbit Alta ®)
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Asan Medical Center
Intracranial Pressure Increase
Change of Optic Nerve Sheath Diameter After Deflation of Pneumatic Tourniquet
The purpose of this study is to evaluate the change of the optic nerve sheath diameter after deflation of pneumatic tourniquet.
- Trial name
- NCT03782077
- Testing
- Deflation of pneumatic tourniquet
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Regional Anesthesia
Comparison of 0.375% Ropivacaine and 0.25% Levobupivacaine for Infraclavicular Brachial Plexus Block
Infraclavicular brachial plexus block has been used more frequently with the development of high-resolution ultrasound. Compared with peripheral nerve block using landmark technique or nerve stimulator technique…
- Trial name
- NCT03679897
- Testing
- Ropivacaine solution, Levobupivacaine solution
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Asan Medical Center
Sciatic Nerve Block
The Effect of Leg Position on the Sciatic Nerve on Sonogram
Little is known about which posture of lower extremity makes it easier to access to the sciatic nerve. In this study, the investigators aimed to identify the most appropriate positioning of the lower extremity during…
- Trial name
- NCT03678961
- Testing
- external rotation of leg, hip flexion and knee flexion
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Asan Medical Center
Cleft Palate
Optic Nerve Sheath Diameter in Patients Undergoing Palatoplasty
The purpose of this study is to evaluate the change of the optic nerve sheath diameter according to the change of the neck position in pediatric patients undergoing palatoplasty.
- Trial name
- NCT03585608
- Testing
- Neck extension
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Diabetes
Blood Flow Change After Free Flap Surgery in Diabetic Patients
We aim to evaluate the flow change of arterial anastomosis site during free flap surgery in diabetic patients.
- Trial name
- NCT03027219
- Testing
- Alprostadil
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Asan Medical Center