Clinical trials: sponsored by Asan Medical Center
Benign Uterine Disease
Study on Bladder and Sexual Function Change After Simple Hysterectomy
To evaluate the incidence and pattern of bladder symptoms and sexual function change occuring after simple hysterectomy and to analyze the influence of bladder symptoms and sexual function change on quality of life of patients.
- Trial name
- NCT01683890
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Advanced Ovarian Cancer
Efficacy Study of Neoadjuvant Chemotherapy to Treat Advanced Ovarian Cancer
Neoadjuvant chemotherapy is alternative treatment option to upfront cytoreductive surgery to treat advanced ovarian cancer. Paclitaxel plus carboplatin is most frequently selected chemotherapeutic regimen for neoadjuvant…
- Trial name
- NCT01462149
- Testing
- Neoadjuvant chemotherapy, Carboplatin
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Asan Medical Center
Cervical Cancer
Impact of Sonifilan on the Quality of Life in Patients With Cervical Cancer During Radiation or Chemoradiation Therapy
The impact of sonifilan on the quality of life in patients with cervical cancer during radiation or chemoradiation therapy 1. Primary endpoint : Quality of life 2.
- Trial name
- NCT01926821
- Testing
- Sonifilan
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Cervical Cancer
The Efficacy and Safety of Nerve-sparing Radical Hysterectomy in Cervical Cancer
To develope nerve sparing radical hysterectomy for treatment of cervical cancer to minimize the complication of radical hysterectomy and to maximize quality of life and to evaluate the feasibility and efficacy by prospective…
- Trial name
- NSRHCXCA (NCT01893333)
- Testing
- Nerve sparing radical hysterectomy
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Asan Medical Center
Benign Ovarian or Tubal Disease
Study of Laparoendoscopic Single Site Adnexal Surgery for Benign Ovarian and Tubal Disease
To compare the safety and efficacy between single-port and three-port adnexal surgery in patients with benign ovarian and tubal disease
- Trial name
- NCT01679509
- Testing
- Single-port laparoscopic adnexal surgery, Three-port laparoscopic adnexal surgery
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Asan Medical Center
Endometrial Cancer
Efficacy Study of Chemotherapy Followed by Radiation Therapy to Treat Endometrial Cancer
Previous some studies suggested the addition of chemotherapy to radiation therapy after surgery may have survival benefit in patients with high risk endometrial cancer.
- Trial name
- NCT01461746
- Testing
- Docetaxel, Cisplatin, Radiation therapy
- Where
- South Korea
- Volunteers
- 67 people
- Sponsor
- Asan Medical Center
Hepatocellular Carcinoma
Quality of Life in Patients With Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading cause of cancer-related mortality worldwide.
- Trial name
- NCT02420678
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Haploidentical Hematopoietic Stem Cell Transplantation, Malignant Disease
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation in Children and Adolescents
Purpose of study: This phase I/II trial is to evaluate the safety and feasibility of TCRαβ-depleted graft from haploidentical family donors in treating children and adolescents with malignant or non-malignant diseases.
- Conditions
- Haploidentical Hematopoietic Stem Cell Transplantation, Malignant Disease, Non-malignant Disease
- Trial name
- NCT02014506
- Testing
- Fludarabine, Cyclophosphamide, anti-thymocyte globulin
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Kidney Transplantation
Treatment of the optImuM Dose of calcineUrin Inhibitor and Mycophenolate Sodium in Kidney Recipients
To clarify that tacrolimus-sparing regimen with minimal tacrolimus dose together with mycophenolate sodium dose increment will preserve renal allograft function without rising adverse effects Primary endpoints: 1.
- Trial name
- OPTIMUM (NCT01159080)
- Testing
- routine dose tacrolimus and less myfortic, reduced dose tacrolimus and conventional myfortic
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Asan Medical Center
Brain Ischemia
Strategy for Adequate Blood Pressure Lowering in the Patients With Intracranial Atherosclerosis
To develop adequate blood pressure (BP) lowering strategy after subacute ischemic stroke patients with symptomatic severe intracranial atherosclerosis.
- Trial name
- STABLE-ICAS (NCT01104311)
- Testing
- Aggressive BP lowering, modest blood pressure lowering
- Where
- 16 sites in South Korea
- Volunteers
- 132 people
- Sponsor
- Asan Medical Center
Frailty
Multifactorial Intervention on Frailty in Vulnerable Older Adults
Frailty is a highly prevalent, progressive condition in older adults that is characterized by multisystem physiologic impairments and vulnerability to stressful events, leading to increased risk of geriatric conditions…
- Trial name
- ASPRA-IS (NCT02554994)
- Testing
- Multifactorial intervention, Usual care
- Where
- 2 sites in South Korea
- Volunteers
- 187 people
- Sponsor
- Asan Medical Center
ICU-acquired Weakness
Safety and Efficacy of an Early Rehabilitation Program in Surgical Intensive Care Unit
The purpose of this study is to determine whether an early rehabilitation program in surgical intensive care unit is safe and effective in preventing critical care illness and intensive care unit acquired weakness.
- Trial name
- ERP (NCT03055949)
- Testing
- Early rehabilitation program
- Volunteers
- 131 people
- Sponsor
- Asan Medical Center
Ischemic Stroke, Transient Ischemic Attack
Rivaroxaban Versus Warfarin in Acute Ischemic Stroke With Atrial Fibrillation
Rationale Acute ischemic stroke due to atrial fibrillation (AF) carries a high risk for early recurrence. In acute stage, guidelines recommend aspirin, but do not recommend anticoagulation due to the increased risk of…
- Trial name
- TripleAXEL (NCT02042534)
- Testing
- Rivaroxaban, Warfarin
- Where
- South Korea
- Volunteers
- 195 people
- Sponsor
- Asan Medical Center
Chronic Viral Hepatitis B Without Delta-agent
Telbivudine Versus Entecavir in Reducing Serum HBsAg Levels in Patients With HBeAg-positive Chronic Hepatitis B
The goal of chronic hepatitis B (CHB) treatment is complete and permanent eradication of hepatitis B virus (HBV) from patient's body, which is best represented by serum HBsAg loss accompanied by undetectable serum HBV DNA level.
- Trial name
- TERESA (NCT01595685)
- Testing
- Telbivudine, Entecavir
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Asan Medical Center
Delirium, Trauma
Incidence and Risk Factors for Delirium in Severely Injured Patients
Delirium is very common in intensive care unit (ICU) patients and leads to poor outcomes. There is little information on delirium in injured patients however.
- Conditions
- Delirium, Trauma, Intensive Care Unit Syndrome
- Trial name
- NCT03023839
- Where
- South Korea
- Volunteers
- 179 people
- Sponsor
- Asan Medical Center
Achalasia
Clinical Outcomes of Peroral Endoscopic Myotomy
Esophageal outflow obstruction is characterized by failure to relax the lower esophageal sphincter (LES), resulting in impaired flow of ingested food into the stomach.
- Trial name
- NCT02989883
- Testing
- peroral endoscopic myotomy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Recurrent Breast Cancer, Stage IV Breast Cancer
Diagnostic Accuracy and Safety Study of FES PET/CT in Assessment of ER Status of Recurrent or Metastatic Breast Cancer
The standard diagnostic workup for recurrent or metastatic breast cancer includes biopsy and determination of tumor estrogen status according to National Comprehensive Cancer Network and European Society for Medical Oncology.
- Trial name
- NCT01986569
- Testing
- [18F]fluoroestradiol (FES)
- Where
- South Korea
- Volunteers
- 93 people
- Sponsor
- Asan Medical Center
Gastric Cancer
Serum Cholesterol and Gastric Neoplasm
Investigators have a plan to conduct nested case-control study to investigate the association between serum cholesterol levels including TC, HDL-C, LDL-C, triglyceride (TG), apolipoproteins and gastric neoplasm.
- Trial name
- SCGN (NCT02041312)
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 1,178 people
- Sponsor
- Asan Medical Center
Helicobacter Infections
Helicobacter Pylori and Proton Pump Inhibitor
The purpose of this study is to know the distribution of HP in stomach before use of PPI, during use of PPI, and after stop of PPI.
- Trial name
- NCT02449941
- Testing
- PPI (proton pump inhibitor)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Helicobacter Infection
Comparison of 7-day and 14-day Bismuth Based Quadruple Therapy for Secondary Helicobacter Pylori Eradication
At present, triple therapy are recommended by various guidelines for the treatment of Helicobacter pylori (H. pylori) infection.
- Trial name
- NCT00841854
- Testing
- pantoprazole, bismuth, metronidazole
- Where
- South Korea
- Volunteers
- 199 people
- Sponsor
- Asan Medical Center