Clinical trials: sponsored by Asan Medical Center
Efficacy, Safety
EUS-guided Ethanol-lipiodol Ablation of Pancreatic Neuroendocrine Tumor: a Prospective Study
The present study evaluate the safety and efficacy of EUS-guided ethanol-lipiodol ablation for the treatment of pancreatic NET
- Conditions
- Efficacy, Safety, Feasibility
- Trial name
- EUS (NCT01902238)
- Testing
- EUS-guided ethanol-lipiodol mixture ablation
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Asan Medical Center
Helicobacter Pylori Infection, Peptic Ulcer
Helicobacter Pylori Antibiotic Susceptibility Testing of Korea
The purpose of this study is to make nationwide registry for antimicrobial resistance of Helicobacter pylori using single method with agar dilution in Korea.
- Conditions
- Helicobacter Pylori Infection, Peptic Ulcer, Lymphoma, Gastric Cancer
- Trial name
- NCT02961296
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Asan Medical Center
Hypoxia, Oxygen Therapy
Regional Ventilation During High Flow Nasal Cannula and Conventional Nasal Cannula in Patients With Hypoxia
High-flow nasal cannula (HFNC) that uses heated and humidified oxygen was recently introduced for bedside care. It has been shown to be associated with reduced risks of tracheal intubation rates and mortality in adult hypoxic…
- Conditions
- Hypoxia, Oxygen Therapy, High Flow Nasal Cannula, Ventilation
- Trial name
- NCT02943863
- Testing
- HFNC followed by conventional nasal cannula, Conventional nasal cannula followed by HFNC
- Volunteers
- 24 people
- Sponsor
- Asan Medical Center
Hypertension, Cardiovascular Risk
Effect of Pitavastatin on Coronary Flow Reserve in Hypertensive Patients
Although statins reduce cardiac events in hypertensive patients with cardiovascular risk factors, the effect of statins on coronary flow reserve (CFR) has not been examined in such patients.
- Trial name
- EPOCH (NCT02144922)
- Testing
- Pitavastatin, Control
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Asan Medical Center
Cerebral Arterial Diseases, Dissecting Aneurysm of Cerebral Artery
Prospective Observation for Serial Changes of Acute Intracranial Artery Dissection Using High Resolution MRI
Intracranial artery disease has been more detected with development of HR-MR. HR-MR can depict vascular wall directly and give us more information beyond the pre-existing imaging modalities such as digital subtraction…
- Conditions
- Cerebral Arterial Diseases, Dissecting Aneurysm of Cerebral Artery, Intimal Dissection
- Trial name
- NCT02914288
- Testing
- High resolution magnetic resonance imaging for intracranial vessel walls
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Cystic Tumors of the Pancreas
Long Term Outcomes After EUS-guided Ablation for Cystic Tumors of the Pancreas
Cystic lesions of the pancreas are defined as round, fluid-filled structures within the pancreas detected by radiologic imaging.
- Trial name
- EUS-EP (NCT00689715)
- Testing
- Endoscopic ultrasonography-guided ethanol lavage with paclitaxel injection
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Diffuse Large B-cell Lymphoma
Abbreviated R-CHOP in Completely Excised Stage I or II DLBCL
This study aims; to assess the efficacy of shortened systemic chemotherapy in patients with completely excised CD20 positive Diffuse Large B-cell Lymphoma (DLBCL) with Ann Arbor Stage I or II.
- Trial name
- NCT01279902
- Testing
- Rituximab plus CHOP Immunochemotherapy
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Asan Medical Center
Multiple Myeloma
Pharmacokinetic and Pharmacodynamic Study of Lenograstim for Hematopoietic Stem Cell Mobilization
Twenty four patients with multiple myeloma will be randomized to either AM group (administration of lenograstim at 8 am) or PM group (administration of lenograstim at 6 am ).
- Trial name
- NCT02184897
- Testing
- lenograstim 10 microgram/kg/day
- Where
- 2 sites in South Korea
- Volunteers
- 24 people
- Sponsor
- Asan Medical Center
IPMN
Intraductal Papillary Mucinous Neoplasm With Malignant Change
Purpose: To investigate diagnostic performance of CT and MR in intraductal papillary mucinous neoplasm with malignant change according to international consensus guidelines 2012.
- Trial name
- NCT02044926
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Asan Medical Center
Parkinson Disease, Sleep Disorders
Clock and Narcolepsy Genetic Variants and the Effects of Stalevo® (Levodopa/Carbidopa/Entacapone) on Sleep Disorders in Parkinson's Disease
The purpose of this study is to investigate the genetic variants of clock and narcolepsy genes that determine the therapeutic effects of Stalevo® on the quality of sleep in patients with Parkinson's Disease.
- Trial name
- NCT02452606
- Testing
- Stalevo®
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Crohn's Disease, Ulcerative Colitis
Safety of Accelerated Infliximab Infusions in Patients With Inflammatory Bowel Disease (IBD)
This study aims to test the hypothesis that the accelerated infusion of infliximab is not inferior to the conventional 2 hour infusion with respect to the frequency of infusion reaction.
- Trial name
- NCT01346826
- Testing
- Standard 2 hours-infusion, Accelerated 1 hour-infusion, Accelerated 30 minutes-infusion
- Where
- South Korea
- Volunteers
- 145 people
- Sponsor
- Asan Medical Center
Hypoxic Ischemic Encephalopathy
Targeted Temperature Management After In-Hospital Cardiac Arrest
The purpose of this study is to determine whether targeted temperature management at 36.0˚C(TTM-36) in patients who remain unconscious after resuscitation from in-hospital cardiac arrest(IHCA) will reduce death and disability…
- Trial name
- TTM36-IHCA (NCT02578823)
- Testing
- Arctic Sun®, Arcticgel™, Conventional antipyretic treatment
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Crohn's Disease, Intestinal Tuberculosis
Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease
The aim of this study is to develop a scoring system and a prediction model for differential diagnosis between intestinal tuberculosis and Crohn's disease.
- Trial name
- NCT01392365
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Asan Medical Center
Gastric Cancer
Study of Gastroduodenal Metallic Stent vs Gastrojejunostomy
Selection of the optimal treatment for gastric outlet obstruction in patients with radically unresectable gastric cancer remains controversial because previous studies comparing the two procedures had a small sample size as well…
- Trial name
- NCT02784470
- Testing
- gastroduodenal stent placement, gastrojejunostomy
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Asan Medical Center
Non Functioning Pancreatic Endocrine Tumor
Clinical Effectiveness of Serum Chromogranin A Levels on Diagnostic of Pancreatic Neuroendocrine Tumors
Chromogranin A (CgA) is a glycoprotein with a molecular weight of 49 to 52 kDa produced by chromaffin cells of the adrenal medulla, enterochromaffin-like (ECL) cells, and endocrine cells of the stomach and pancreas, and it is the…
- Trial name
- CgA (NCT02759718)
- Testing
- Chromogranin A
- Volunteers
- 111 people
- Sponsor
- Asan Medical Center
Benign Neoplasm of Body of Pancreas, Benign Neoplasm of Tail of Pancreas
Validation of 3 Dimensional Laparoscopic System in Disral Pancreatectomy and Splenectomy
Traditionally, laparoscopy has been based on 2-dimensional (2D) imaging, which has represented a considerable challenge for those approaching this technique.
- Trial name
- NCT02757690
- Testing
- 3-dimensional distal pancreatectomy, 2-dimensional distal pancreatectomy
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Diffuse Large B Cell Lymphoma
Bendamustine Plus Subcutaneous Rituximab in Patients With Diffuse Large B-cell Lymphoma
This is an open-label, multi-center, prospective, single arm phase 2 trial of the combination of bendamustine and rituximab in patients with PTLD, monomorphic cluster of differentiation antigen 20(CD20) positive DLBCL.
- Trial name
- PTLD (NCT02753062)
- Testing
- bendamustine, rituximab
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Asan Medical Center
Treatment Response, Adverse Events
Photodynamic Therapy in Locally Advanced Hilar Cholangiocarcinoma
To determine the safety and efficacy of photodynamic therapy with a novel photosensitizer and a flexible laser probe in locally advanced hilar cholangiocarcinoma.
- Conditions
- Treatment Response, Adverse Events, Feasibility
- Trial name
- PDT (NCT02725073)
- Testing
- Photodynamic therapy
- Where
- 2 sites in South Korea
- Volunteers
- 32 people
- Sponsor
- Asan Medical Center
Kidney Neoplasm
[18F]Fluciclatide PET Imaging of Pazopanib Response
Positron emission tomography (PET) is a non-invasive imaging tool for monitoring functional and metabolic responses of biological events with specific radiotracer in vivo.
- Trial name
- NCT01961583
- Testing
- 18F-Fluciclatide
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Asan Medical Center
Diffuse Large B-cell Lymphoma
R-CHOP Alone vs. R-CHOP Plus Radiotherapy for Localized CD20+ DLBCL
To compare the efficacy and safety of chemotherapy alone and combined modality therapy in the treatment of localized CD20 (+) diffuse large B-cell lymphoma
- Trial name
- ASPIRE (NCT02054559)
- Testing
- R-CHOP, Radiotherapy
- Where
- South Korea
- Sponsor
- Asan Medical Center