Clinical trials: sponsored by Asan Medical Center
Non-Hodgkin's Lymphoma
Zevalin Plus BuCyE High-dose Therapy in B-cell Non-Hodgkin's Lymphoma
In order to improve the clinical result of high-dose chemotherapy and autologous stem cell transplantation for B-cell non-Hodgkin's lymphoma, Zevalin will be added to the conditioning regimen.
- Trial name
- NCT00336843
- Testing
- Zevalin-BuCyE
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Asan Medical Center
Non-Hodgkin's Lymphoma, Marginal Zone Lymphoma
Gemcitabine for Marginal Zone Lymphoma
Marginal zone lymphoma, one of the indolent lymphoma, is believed to be incurable with chemotherapy. Thus the investigators need a novel agent for marginal zone lymphoma.
- Trial name
- NCT00337259
- Testing
- gemcitabine
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Asan Medical Center
Urinary Bladder, Overactive, Overactive Bladder
Solifenacin Flexible Dosing Study in Frequent Micturition Patients With and Without Urgency
The purpose of the study is to compare the effect of solifenacin succinate between frequent micturition patients with urgency and those without urgency.
- Trial name
- NCT00979472
- Testing
- Solifenacin
- Where
- 9 sites in South Korea
- Volunteers
- 291 people
- Sponsor
- Asan Medical Center
Parkinson's Disease
Efficacy and Safety of F-18 FPCIT PET in Parkinson's Disease and Essential Tremor Patients
The purpose of this study is to determine whether F-18 FPCIT is effective and safe radiopharmaceutical for the objective diagnosis of Parkinson's disease.
- Trial name
- FPCIT (NCT00468078)
- Testing
- PET/CT, F-18 FPCIT
- Where
- South Korea
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Respiratory Distress Syndrome, Adult
Mesenchymal Stem Cell in Patients With Acute Severe Respiratory Failure
Although the advent of advanced medical support for respiratory failure, the mortality rate of acute severe respiratory failure is still high and the life quality is frequently compromised from pulmonary fibrosis.
- Trial name
- STELLAR (NCT02112500)
- Testing
- Mesenchymal Stem Cell
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Asan Medical Center
Leukemia
Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in Remission
RATIONALE: Giving chemotherapy before a donor bone marrow or peripheral blood stem cell transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells.
- Trial name
- NCT01020734
- Testing
- anti-thymocyte globulin, busulfan, cyclophosphamide
- Where
- 2 sites in South Korea
- Volunteers
- 263 people
- Sponsor
- Asan Medical Center
Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia
Safety and Efficacy Study of Donor Natural Killer Cells Given After Haploidentical Hematopoietic Cell Transplantation
The protocol treatment is to evaluate clinical effects of donor-derived natural killer cells that are given after HLA-mismatched hematopoietic cell transplantation.
- Trial name
- DNKI-II (NCT01795378)
- Testing
- donor natural killer cell infusion
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Asan Medical Center
Leukemia, Myelodysplastic Syndromes
Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome
RATIONALE: Giving low doses of chemotherapy and antithymocyte globulin before a donor stem cell transplant helps stop the growth of abnormal cells.
- Conditions
- Leukemia, Myelodysplastic Syndromes, Nonmalignant Neoplasm, Paroxysmal Nocturnal Hemoglobinuria
- Trial name
- NCT00731328
- Testing
- nonmyeloablative allogeneic hematopoietic stem cell transplantation
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Asan Medical Center
Hypertension
A Trial of Fimasartan for Early Diastolic Heart Failure
Approximately half of hypertensive patients have diastolic dysfunction and diastolic dysfunction is associated with development of congestive heart failure and increased mortality.
- Trial name
- FINE (NCT01691118)
- Testing
- Fimasartan, Antihypertensive treatment
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Hepatitis B, Chronic
Compare Continuing Lamivudine Plus Adefovir or Adefovir Versus Switching to Entecavir Plus Adefovir in Patients With LAM-resistant Chronic Hepatitis B
The purpose of this study is to compare efficacy and safety of continuing Lamivudine plus Adefovir or Adefovir versus switching to Entecavir plus Adefovir in patients with LAM-resistant chronic hepatitis B who have suboptimal…
- Trial name
- NCT02482272
- Testing
- Lamivudine, Adefovir, Entecavir
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Asan Medical Center
Bladder Cancer
Effect of SVV Guided Fluid Therapy on Blood Loss and Postoperative Outcomes
The purpose of this study is to investigate the effect of stroke volume variation (SVV) guided fluid therapy on the blood loss and postoperative outcomes in radical cystectomy.
- Trial name
- NCT02373735
- Testing
- crystalloid, colloid, mannitol
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Asan Medical Center
Brain Ischemia, Intracranial Hemorrhages
PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study
Through this study, the investigators are to prove that Cilostazol effectively prevent progression of intima-medial thickness in ischemic stroke patients with high risk of cerebral hemorrhage, along with no significant increase…
- Trial name
- PICASSO-IMT (NCT02483169)
- Testing
- cilostazol, Probucol, Aspirin
- Volunteers
- 800 people
- Sponsor
- Asan Medical Center
Brain Ischemia, Intracranial Hemorrhages
PreventIon of CArdiovascular Events in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage
Through this study, the investigators are to prove that Cilostazol effectively prevent cardiovascular events in ischemic stroke patients with high risk of cerebral hemorrhage, along with no significant increase in the risk of…
- Trial name
- PICASSO (NCT01013532)
- Testing
- Cilostazol, Probucol, Aspirin
- Where
- 71 sites in China, Philippines and 1 more
- Volunteers
- 1,600 people
- Sponsor
- Asan Medical Center
Other Surgical Procedures
Effects of PEEP on Optic Nerve Sheath Diameter During Robot-Assisted Laparoscopic Prostatectomy
The investigators aim to investigate the effects of positive end-expiratory pressure ventilation on intracranial pressure assessed by sonographic optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic…
- Trial name
- NCT02516566
- Testing
- PEEP
- Volunteers
- 38 people
- Sponsor
- Asan Medical Center
Prostate Cancer
Comparison Between Conventional and Model-based Infusion Strategy of IV PCA in Patients Undergoing RALP
Comparing postoperative analgesics requirements and complications between conventional and model-based infusion strategy of intravenous patient-controlled analgesia in patients who undergoing robot assisted laparoscopic radical…
- Trial name
- NCT02402621
- Testing
- fentanyl
- Where
- South Korea
- Volunteers
- 111 people
- Sponsor
- Asan Medical Center
Bone Marrow Transplantation
Assessment of CMV-specific ELISPOT Assay for Predicting CMV Infection in Bone Marrow Transplant Recipients (ACE-BMT)
CMV is one of the most important opportunistic infection in transplant recipients. In South Korea, more than 95% of adults reveal sero-positivity for CMV IgG.
- Trial name
- NCT02081716
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Asan Medical Center
Fibrosis, Liver
Comparison of Smart-Shear Wave Elastography and Transient Elastography
The aim of this prospective study was to evaluate the applicability and diagnostic performances of Smart-Shear wave(SSW) imaging, in comparison with Transient elastography(TE) for the staging of liver fibrosis using pathologic…
- Trial name
- SMART (NCT02569567)
- Testing
- Smart-Shear Wave(SSW) imaging, Transient elastography(TE)
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Asan Medical Center
Hepatocellular Carcinoma
The Effect of Telephone Counseling on the Compliance and Satisfaction for Advanced HCC Patients Receiving Sorafenib
Sorafenib is an oral multikinase inhibitor with antiproliferative and antiangiogenic effects used as systemic treatment in patients with unresectable hepatocellular carcinoma.
- Trial name
- SORATEL (NCT02564666)
- Testing
- telephone counseling
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Asan Medical Center
Kidney Transplantation Recipients
Assessment of CMV-specific ELISPOT Assay for Predicting CMV Infection in Kidney Transplant Recipients
CMV is one of the most important opportunistic infection in transplant recipients. In South Korea, more than 95% of adults reveal sero-positivity for CMV IgG.
- Trial name
- ACE-KT (NCT02025335)
- Where
- South Korea
- Volunteers
- 199 people
- Sponsor
- Asan Medical Center
Toxic Maculopathy
Incidence and Risk Factor of Hydroxychloroquine and Chloroquine Retinopathy
The purpose of this study is to evaluate the incidence and risk factor of toxic maculopathy who treated with hydroxychloroquine or chloroquine due to their autoimmune disease such as rheumatoid arthritis or systemic lupus…
- Trial name
- NCT02550964
- Testing
- Composite Examination
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Asan Medical Center