Clinical trials: sponsored by Asan Medical Center
Hematologic Disease, Solid Organ Transplantation
Radiologic Features of Invasive Pulmonary Aspergillosis
Invasive pulmonary aspergillosis (IPA) is an opportunistic infection that primarily affects recipients of solid organ transplants (SOTs) and patients with chemotherapy- induced neutropenia.Although both of these populations are…
- Trial name
- NCT01178177
- Volunteers
- 130 people
- Sponsor
- Asan Medical Center
Soft Tissue Sarcomas, Bone Sarcomas
RAD001 in Advanced Sarcoma
This trial intends to test the efficacy and safety of RAD001 in patients with advanced sarcoma who failed to conventional chemotherapy.
- Trial name
- NCT01830153
- Testing
- RAD001
- Where
- 8 sites in South Korea
- Volunteers
- 41 people
- Sponsor
- Asan Medical Center
Malignant Ureteral Obstruction
Comparison of Silicone-covered Metallic Ureteral Stent and Double-J Stent for Malignant Ureteral Obstruction
Malignant ureteral obstruction often necessitates chronic urinary diversion and is associated with high rates of failure with traditional double-J ureteral stents.
- Trial name
- NCT01823575
- Testing
- Silicone-covered metallic stent, Double-J stent
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Asan Medical Center
Leukemia, Lymphoma
Donor Stem Cell Transplant After Conditioning Therapy in Treating Patients With Hematologic Cancer, Recurrent or Metastatic Solid Tumor, or Other Disease
RATIONALE: Giving chemotherapy before a donor stem cell transplant helps stop the growth of cancer or abnormal cells. It also helps stop the patient's immune system from rejecting the donor's stem cells.
- Conditions
- Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
- Trial name
- NCT00521430
- Testing
- anti-thymocyte globulin, busulfan, cyclosporine
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Leukemia
Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
RATIONALE: Giving chemotherapy before a donor stem cell transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells.
- Trial name
- NCT00618501
- Testing
- cytarabine, daunorubicin hydrochloride, etoposide
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Cancer
Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant
RATIONALE: Giving donor natural killer cells to patients who have undergone donor bone marrow transplant may make the transplant work better and keep cancer cells from coming back.
- Trial name
- NCT00569283
- Testing
- therapeutic allogeneic lymphocytes
- Where
- 2 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- Asan Medical Center
Leukemia, Myelodysplastic Syndromes
Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematological Cancer
RATIONALE: Giving chemotherapy before a donor bone marrow stem cell transplant helps stop the growth of cancer cells. Chemotherapy and antithymocyte globulin stop the patient's immune system from rejecting the donor's stem cells.
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
- Trial name
- NCT00627666
- Testing
- anti-thymocyte globulin, busulfan, fludarabine phosphate
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Inflammatory Bowel Disease, Crohn's Disease
Immunogenicity of Hepatitis A Vaccine in Inflammatory Bowel Disease (IBD) Patients
The purpose of this study is to measure the immune response in 18-40 year old IBD patients after receiving the hepatitis A vaccine.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis, Hepatitis A
- Trial name
- NCT01341808
- Testing
- Epaxal Berna (virosomal hepatitis A vaccine)
- Where
- South Korea
- Volunteers
- 493 people
- Sponsor
- Asan Medical Center
Lymphoma, Large-Cell, Diffuse, Lymphoma, B-Cell
Bortezomib Plus CHOP Every 2 Weeks for Advanced Stage DLBCL
Diffuse large B-cell lymphoma is a most prevalent non-Hodgkin's lymphoma. Recently the clinical results have been improved with new drugs and new modalities such as cyclophosphamide, doxorubicin, vincristine, and prednisone…
- Trial name
- NCT00379574
- Testing
- Bortezomib, Cyclophosphamide, Doxorubicin
- Where
- 2 sites in South Korea
- Volunteers
- 49 people
- Sponsor
- Asan Medical Center
Metastatic Colorectal Cancer
Second-line FOLFOX With or Without Regorafenib in mCRC Patients Failed to First-line Irinotecan Plus Fluoropyrimidines
Regorafenib has been proved to improved survival in patients with metastatic colorectal cancer who have been failed to all of known standard chemotherapy (The CORRECT study).
- Trial name
- NCT01786538
- Testing
- Regorafenib/FOLFOX
- Where
- South Korea
- Sponsor
- Asan Medical Center
Healthy Individual
Pharmacokinetic, Pharmacodynamic Profiles and Safety After Oral Administration of Ivabradine in Male Healthy Korean Volunteers
1. To assess the pharmacokinetic profile of ivabradine (S 16257) and its main active metabolite S 18982 in Korean healthy volunteers after oral administration of ivabradine at the doses of 2.5, 5, 10mg and after repeated oral…
- Trial name
- NCT01804010
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer
RATIONALE: Giving an infusion of natural killer cells from a donor after a donor stem cell transplant may help kill any remaining cancer cells after the transplant.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00823524
- Testing
- donor natural killer cell infusion
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Asan Medical Center
Colonoscopy Failure, Poor Bowel Preparation
Second Bowel Preparation for Colonoscopy Failure
Colonoscopy is a basic but important tool to diagnose and treat lesions of the colon. Proper colon cleansing is essential for colonoscopy to be performed with a good quality.
- Trial name
- NCT01510977
- Testing
- polyethylene glycol, Bisacodyl, polyethylene glycol
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Non-small Cell Lung Cancer
First Line Gefitinib by FDG-PET Metabolic Response
When considering 1st line gefitinib treatment for NSCLC, the investigators need epidermal growth factor receptor (EGFR) mutational status of the tumor.
- Trial name
- NCT01510990
- Testing
- Gefitinib
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Cardiovascular Diseases
In Vitro Interaction Between Ticagrelor and Its Active Metabolite and Their Effects on Salicylic Acid
This is a in-vitro study to evaluate the pharmacodynamic interaction between ticagrelor and its active metabolite (AR-C124910XX) and their effects on the pharmacodynamics of salicylic acid.
- Trial name
- In_vitro_PAT (NCT01777516)
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Non Small Cell Lung Cancer
Paclitaxel/Carboplatin (PC) Followed by Gefitinib Versus PC in Advanced Non-small Cell Lung Cancer
This study compares paclitaxel/carboplatin (PC) to PC chemotherapy followed by gefitinib for 2 weeks in patients with Non-small Cell Lung Cancer (NSCLC) without epidermal growth factor receptor (EGFR) mutations.
- Trial name
- PRIDE (NCT01196234)
- Testing
- Paclitaxel/Carboplatin/Gefitinib, Paclitaxel/Carboplatin
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Asan Medical Center
Metastatic Colorectal Cancer
Phase II Study of Bevacizumab, Capecitabine and Oxaliplatin in Colon Cancer
The purpose of this study is to determine the efficacy and safety of bevacizumab/capecitabine/oxaliplatin combination in metastatic or recurrent Korean colorectal cancer.
- Trial name
- NCT00378066
- Testing
- Bevacizumab
- Where
- 6 sites in South Korea
- Volunteers
- 49 people
- Sponsor
- Asan Medical Center
Trauma
Nutritional Requirement for the Severe Trauma Patients
After severe trauma, high caloric nutrition supplement do harm on metabolic and immunologic aspects.
- Trial name
- NCT01760135
- Testing
- high caloric nutritional supplement, low caloric nutritional supplement
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Asan Medical Center
Acquired Aplastic Anemia
Haploidentical Stem Cell Transplantation for Children With Acquired Severe Aplastic Anemia
Rationale: Fludarabine, cyclophosphamide, anti-thymocyte globulin and low-dose total body irradiation (LD-TBI) may induce the engraftment cross the immunologic barrier in the setting of HLA-haploidentical allogeneic hematopoietic…
- Trial name
- NCT01759732
- Testing
- Fludarabine, Cyclophosphamide, anti-thymocyte globulin
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Asan Medical Center
Pancreaticoduodenectomy
Comparison of Hemodynamic Effects of Two Colloid Therapies in Post-operative Patients Undergoing Pancreaticoduodenectomy
From postoperative patients having undergone pancreaticoduodenectomy; 1. To compare the hemodynamic parameters from the patient administrated 5% HA and 6% Voluven 2.
- Trial name
- NCT01758172
- Testing
- 6% hydroxyethyl starch 130/0.4, Albumin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center