Clinical trials: sponsored by Asan Medical Center
Aplastic Anemia
Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Aplastic Anemia
Rationale: Chemotherapy with fludarabine, cyclophosphamide and anti-thymocyte globulin may induce the engraftment cross the immunologic barrier in the setting of HLA-haploidentical allogeneic hematopoietic cell transplantation.
- Trial name
- NCT01105273
- Testing
- anti-thymocyte globulin, filgrastim, Fludarabine
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Asan Medical Center
Early Gastric Cancer, Gastric Dysplasia
Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD?
Aspirin and/or clopidogrel users are increasing due to increased prevalence of cardiovascular or cerebrovascular disease with an aging society in Korea.
- Trial name
- NCT01621451
- Testing
- aspirin and/or clopidogrel
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Asan Medical Center
Metastatic Colorectal Cancer
Post-First Progression Use of Bevacizumab in Metastatic Colorectal Cancer (mCRC)
Bevacizumab beyond progression has been proven to be safe in the community setting (BRiTE) and in the post-marketing study (BEAT), and confirmed its efficacy and safety in the first line with all regimens of chemotherapy.
- Trial name
- SAFE (NCT00862342)
- Testing
- Bevacizumab (Avastin)
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Asan Medical Center
Leukemia, Myelodysplastic Syndromes
Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematologic Cancer or Myelodysplastic Syndrome
RATIONALE: Giving low doses of chemotherapy and antithymocyte globulin before a donor stem cell transplant helps stop the growth of cancer and abnormal cells.
- Trial name
- NCT00732316
- Testing
- nonmyeloablative allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Asan Medical Center
Cardiovascular Diseases
Hyperbilirubinemia After Cardiac Surgery
This study aims to evaluate the incidence and risk factors of hyperbilirubinemia following major cardiac or thoracic aorta surgery, and to determine the clinical impacts of the hyperbilirubinemia on postoperative mortality and…
- Trial name
- NCT01617902
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Asan Medical Center
Chronic Hepatitis C
Efficacy and Effectiveness of PegInterferon and Ribavirin in Korean Patients With Chronic Hepatitis C
The purpose of this study is to investigate the efficacy and effectiveness of peginterferon alfa-2a and ribavirin therapy in Korean chronic hepatitis C patients.
- Trial name
- NCT01596517
- Testing
- Peginterferon alfa-2a plus ribavirin for HCV genotype 1, Peginterferon alfa-2a plus ribavirin for HCV genotype 2/3
- Where
- South Korea
- Volunteers
- 272 people
- Sponsor
- Asan Medical Center
Non-small Cell Lung Cancer
Pemetrexed With or Without Carboplatin for Elderly Non-squamous Non-small Cell Lung Cancer
The number of NSCLC patients above 70 years of age who are non-squamous histology is increasing around the world. Although previous guidelines often recommend single agent therapy for NSCLC, recent studies suggest that platinum…
- Trial name
- ACE (NCT01593293)
- Testing
- PemCarbo, Pem only
- Where
- South Korea
- Volunteers
- 266 people
- Sponsor
- Asan Medical Center
Healthy
Population Pharmacokinetics/Pharmacodynamics (PK/PD) of Microemulsion Propofol in Healthy Volunteers
AquafolTM (Daewon Pharmaceutical Co., Ltd., Seoul, Korea) is a microemulsion propofol that has been developed for eliminating lipid solvent-related adverse events of long chain triglyceride emulsion (LCT) propofol (Diprivan®…
- Trial name
- NCT00908726
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Acute Leukemia, Myelodysplastic Syndrome
HLA-haploidentical Hematopoietic Stem Cell Transplantation for Children and Adolescents With Acute Leukemia, Myelodysplastic Syndrome and Solid Tumors
RATIONALE: Conditioning with total body irradiation (TBI) and fludarabine, cyclophosphamide and anti-thymocyte globulin may induce the engraftment cross the immunologic barrier in the setting of HLA-haploidentical allogeneic…
- Conditions
- Acute Leukemia, Myelodysplastic Syndrome, Solid Tumors
- Trial name
- NCT01509300
- Testing
- anti-thymocyte globulin, filgrastim, Total body irradiation
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Asan Medical Center
Castration-resistant Prostate Cancer
The Role of Androgen Deprivation Treatment (ADT) in Docetaxe-Prednisolone Chemotherapy for Castrate-Resistant Prostatic Cancer
The purpose of this study is to assess the androgen deprivation therapy when patients with castration-resistant prostate cancer are treated with docetaxel-based chemotherapy.
- Trial name
- NCT01487902
- Testing
- ADT, No ADT
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Asan Medical Center
Bladder Cancer, Ureter Cancer
Study of Genexol-PM in Patients With Advanced Urothelial Cancer Previously Treated With Gemcitabine and Platinum
Taxane-based chemotherapy is currently one of the most commonly used regimen for salvage chemotherapy in advanced urothelial carcinoma.
- Trial name
- NCT01426126
- Testing
- Genexol PM
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Asan Medical Center
Metastatic Pancreatic Cancer
Randomized Phase II Study of FOLFOX Versus FOLFIRI.3 in Gemcitabine-refractory Pancreatic Cancer
The investigators are to evaluate the efficacy and safety of FOLFOX or FOLFIRI.3 combination chemotherapy as second-line salvage chemotherapy in patients with advanced pancreatic carcinoma.
- Trial name
- NCT00786006
- Testing
- FOLFIRI.3, FOLFOX
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Asan Medical Center
Metastatic Biliary Cancer
Trial of S-1 Plus Cisplatin (SP) Versus Gemcitabine Plus Cisplatin (GP) in Advanced Biliary Tract Adenocarcinoma
To select a better agent between S-1 or gemcitabine in combination with cisplatin for the conventional chemotherapy platform for future development in advanced Biliary Tract Adenocarcinoma (BTA), the investigators conduct a…
- Trial name
- NCT01375972
- Testing
- S-1 plus cisplatin, Gemcitabine plus Cisplatin
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Asan Medical Center
Pancreatic Cancer
Neoadjuvant FDR GX in Locally Advanced Pancreatic Cancer
The rationale for phase II trial of neoadjuvant fixed dose rate gemcitabine plus capecitabine for patients with LAPC includes the following: First, obtaining a sufficient tumor down-staging to procure R0/R1 resection, reported to…
- Trial name
- NCT01268384
- Testing
- Gemcitabine plus Capecitabine
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Asan Medical Center
Schizophrenia, Metabolic Syndrome
Prevalence of Metabolic Syndrome in Patients With Schizophrenia in Korea
The aim of this study is to examine the prevalence of the Metabolic syndrome(MetS) in Korean patients with schizophrenia. Primary objective: To investigate the prevalence of the MetS in Korean patients with schizophrenia…
- Trial name
- NCT01477918
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Asan Medical Center
Bipolar Disorder, Subsyndromal Depressive Phase
Heart Rate Variability of Patients With Bipolar Disorder in Subsyndromal Depressive Phase
The purposes of this study were: (1) to compare heart rate variability between bipolar patients in subsyndromal depressive phase and healthy controls (2) to evaluate the relation between the severity of subsyndromal depressive…
- Conditions
- Bipolar Disorder, Subsyndromal Depressive Phase, Heart Rate Variability
- Trial name
- NCT01455038
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Colorectal Neoplasms
Study of Prevalence of Colorectal Adenoma in 30- to 49-year-old Subjects With a Family History of Colorectal Cancer
Current guidelines for initiating screening colonoscopies in patients younger than 50 years of age who have a first relative history of colorectal cancer are controversial.
- Trial name
- NCT01428752
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Asan Medical Center
Healthy Volunteers
A Clinical Trial to Evaluate Pharmacokinetics of Daewon DW-ES(A) 625mg/5ml, Daewon DW-ES(B) 625mg/5ml and Megace 800mg/20ml in Healthy Male Volunteers Under Fed Condition
The purpose of this study is to evaluate pharmacokinetics of Daewon DW-ES(A) 625mg/5ml, Daewon DW-ES(B) 625mg/5ml and Megace 800mg/20ml in healthy male volunteers under fed condition.
- Trial name
- NCT01383330
- Testing
- megace, DW-ES(A), DW-ES(B)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Healthy
Drug Interaction and Safety Between Pitavastatin and Valsartan (CWP-PTV-101)
This study is designed to evaluate a pharmacokinetic drug interaction and safety between Pitavastatin and Valsartan in healthy male subjects
- Trial name
- NCT01232049
- Testing
- Multiple Oral Dose of
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Living Donor Liver Transplantation
Population Pharmacokinetics of Fentanyl in Patients Undergoing Living Donor Liver Transplantation
The aim of this study was to characterize pharmacokinetics of fentanyl during and after Living Donor Liver Transplantation (LDLT), using population pharmacokinetic analysis with non linear mixed effects modeling.
- Trial name
- NCT01144312
- Testing
- Fentanyl
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center