Clinical trials: sponsored by Asan Medical Center
Gynecologic Cancer
Patient Blood Mangement (PBM) Using IV Iron in Patients With Gynecologic Cancer
To demonstrate the safety and effectiveness of a patient blood management program in gynecological cancer patients
- Trial name
- NCT05669872
- Testing
- Ferric Carboxymaltose 50Mg/Ml Inj 20Ml, RBC
- Where
- South Korea
- Volunteers
- 334 people
- Sponsor
- Asan Medical Center
Allergic Rhinitis, Cough
Effects of Second-generation Antihistamine Bepotastine on Cough Outcomes in Cough Patients With Allergic Rhinitis
This is a phase 4 study to evaluate the the efficacy of second generation antihistamine on cough outcomes in cough patients with allergic rhinitis.
- Trial name
- NCT04877678
- Testing
- Bepotastine
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Gastrointestinal Stromal Tumors (GISTs)
A Study of Intermittent Dosing Schedule of Imatinib in Patients With Tyrosine Kinase Inhibitor Refractory GISTs
Recent preclinical study has suggested a potential possibility that imatinib might promote tumor growth in the presence of secondary resistance mutations [10].
- Trial name
- NCT02712112
- Testing
- Imatinib Mesylate
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Asan Medical Center
Gastrointestinal Stromal Tumors
PDR001 Plus Imatinib for Metastatic or Unresectable GIST
Assuming that PDR001, an anti-PD-1 antibody, with imatinib might be effective in advanced GIST after failure of standard TKI therapies including imatinib, sunitinib, and regorafenib.
- Trial name
- NCT03609424
- Testing
- PDR001, Imatinib
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Asan Medical Center
Prostate Cancer
Pneumatic Compression and Post-induction Hypotension
The purpose of this study is to evaluate the effect of pneumatic compression on post-induction hypotension in elderly patients undergoing robot assisted laparoscopic prostatectomy.
- Trial name
- NCT05343689
- Testing
- Pneumatic compression
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Scoliosis; Adolescence
Use of Intravenous Acetaminophen in Pediatrics Undergoing Spinal Fusion Surgery
The purpose of this study is to investigate whether perioperative intravenous acetaminophen administration reduces postoperative pain and opioid consumption in adolescents and pediatric patients undergoing spinal fusion surgery.
- Trial name
- NCT04959591
- Testing
- intravenous acetaminophen
- Where
- South Korea
- Volunteers
- 99 people
- Sponsor
- Asan Medical Center
Inflammatory Bowel Disease
Vaccination Status, Knowledge and Attitude in Korean Patients With IBD
The purpose of this study is to investigate the vaccination status, knowledge about vaccination, and attitude to vaccination of the Korean patients with inflammatory bowel diseases
- Trial name
- NCT01984879
- Testing
- Survey with structured questionnaire form for inflammatory bowel disease patient group
- Where
- South Korea
- Volunteers
- 287 people
- Sponsor
- Asan Medical Center
Lumbar Spinal Stenosis, Neurogenic Claudication
Sarcopenia and Outcomes of Neuroplasty in Lumbar Spinal Stenosis
The aim of the present study is to find out the influence of sarcopenia on outcomes of neuroplasty in patients with lumbar spinal stenosis.
- Conditions
- Lumbar Spinal Stenosis, Neurogenic Claudication, Sarcopenia
- Trial name
- NCT04374669
- Testing
- Neuroplasty with Racz catheter
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Asan Medical Center
Remimazolam, Orthopedic Procedures
Effective Dose of Remimazolam for Sedation in Patients Undergoing Lower Extremity Surgery Under Spinal Anesthesia
Currently used drugs for monitored general anesthesia include propofol, midazolam, and dexmedetomidine. Each drug has different advantages and disadvantages.
- Conditions
- Remimazolam, Orthopedic Procedures, Sedatives, Anesthesia, Spinal
- Trial name
- NCT05379777
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Asan Medical Center
Carcinoma, Hepatocellular, Hepatoma
Combination of Regorafenib and Nivolumab in Unresectable Hepatocellular Carcinoma
Regorafenib and nivolumab are proven effective agents for the management of unresectable hepatocellular carcinoma patients. As preclinical studies have suggested potential synergism between antiangiogenic agents and immune…
- Trial name
- RENOBATE (NCT04310709)
- Testing
- Regorafenib/Nivolumab
- Where
- 3 sites in South Korea
- Volunteers
- 42 people
- Sponsor
- Asan Medical Center
Neuroendocrine Tumors, Neuroendocrine Carcinoma
TEMCAP in Grade 3 and Low Ki-67 Gastroenteropancreatic Neuroendocrine Tumors
GI tract including pancreas is the one of most common primary sites of neuroendocrine tumors. Current grading of neuroendocrine tumors are based on the 2010 WHO classification.
- Conditions
- Neuroendocrine Tumors, Neuroendocrine Carcinoma, Temozolomide, Capecitabine
- Trial name
- NCT03079440
- Testing
- TEMCAP
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Asan Medical Center
Cholangiocarcinoma, Biliary Tract Cancer
Adjuvant Capecitabine vs Gemcitabine Plus Cisplatin in Resected Extrahepatic Cholangiocarcinoma
There is no proven adjuvant treatment after curative surgical resection in patients with cholangiocarcinoma, although previous meta-analysis suggested potential survival benefit of adjuvant chemotherapy or radiotherapy in…
- Conditions
- Cholangiocarcinoma, Biliary Tract Cancer, Adjuvant Chemotherapy, Capecitabine
- Trial name
- NCT03079427
- Testing
- Gemcitabine plus cisplatin, Capecitabine
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Asan Medical Center
Endometrial Cancer
Feasibility Study of Laparoendoscopic Single Site Surgical Staging for Endometrial Cancer
To compare the feasibility, safety, and efficacy between single-port and four-port laparoscopic surgical staging in patients with early stage endometrial cancer.
- Trial name
- LESS-E (NCT01679522)
- Testing
- single-port laparoscopic surgical staging, Four-port laparoscopic surgical staging
- Where
- South Korea
- Volunteers
- 107 people
- Sponsor
- Asan Medical Center
Burns, Frailty
Frailty Index and Mortality After a Burn Surgery
Frailty is a condition of a reduced physiological reserve and is associated with postoperative morbidity and mortality. We evaluated the impact of preoperative frailty index (CFI) on 90-day mortality after a burn surgery.
- Trial name
- NCT05613829
- Testing
- Burn surgery
- Where
- South Korea
- Volunteers
- 1,118 people
- Sponsor
- Asan Medical Center
Hepatic Neoplasms, Biliary Tract Neoplasms
Clinical Outcomes of Preoperative and Postoperative Rehabilitation in the Patients With HBP Malignancy
Clinical Outcomes of Preoperative and Postoperative Rehabilitation in the Patients With HBP Malignancy.
- Conditions
- Hepatic Neoplasms, Biliary Tract Neoplasms, Pancreatic Neoplasms
- Trial name
- PReHeBP (NCT02784353)
- Testing
- Perioperative rehabilitation program, Conventional
- Where
- South Korea
- Volunteers
- 158 people
- Sponsor
- Asan Medical Center
Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis
Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View
The aim of the present study is to investigate the safety and clinical utility of contralateral oblique view for fluoroscopic guided cervical epidural access.
- Conditions
- Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis, Cervical Radicular Pain, Herpes Zoster
- Trial name
- NCT04774458
- Testing
- Fluoroscopic-guided cervical epidural access
- Where
- South Korea
- Volunteers
- 439 people
- Sponsor
- Asan Medical Center
Cardiogenic Shock, Extracorporeal Membrane Oxygenation Support
Early LA Venting During Venoaterial ECMO Support
The EVOLVE-ECMO(Early Left Atrial Venting Versus Conventional Treatment For Left VEntricular Decompression During Venoarterial ExtraCorporeal Membrane Oxygenation Support) study is a randomized controlled trial to evaluate the…
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation Support, Refractory Pulmonary Edema
- Trial name
- NCT03740711
- Testing
- Left atrial venting
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Bladder Cancer
Effect of Fresh Gas Flow on Emergence Time
The purpose of this study is to evaluate the effect of fresh gas flow on emergence time in patients undergoing transurethral resection of bladder tumor.
- Trial name
- NCT05376631
- Testing
- Fresh gas flow of 5 L/min, Fresh gas flow of 10 L/min
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Asan Medical Center
Remimazolam, Orthopedic Procedures
ED90 of Remimazolam Loading Dose for Sedation in Patients Under Monitored Anesthetic Care
Currently used drugs for monitored general anesthesia include propofol, midazolam, and dexmedetomidine. Each drug has different advantages and disadvantages.
- Conditions
- Remimazolam, Orthopedic Procedures, Sedatives
- Trial name
- NCT05340335
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Genetic Change, Chemotherapy Effect
Development of Biomarker for the Evaluation of Response After Neoadjuvant Therapy in Patients With Pancreatic Cancer
The purpose of this study is to identify and apply biomarkers that can provide better information than previous imaging and blood tests when evaluating the response after neoadjuvant chemotherapy in pancreatic cancer patients who…
- Conditions
- Genetic Change, Chemotherapy Effect, Pancreatic Cancer
- Trial name
- NCT04110769
- Testing
- next generation sequencing, following next generation sequencing
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Asan Medical Center