Clinical trials: sponsored by Beijing Anzhen Hospital
Coronary Artery Disease, Carotid Artery Stenosis
A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis
This prospective observational cohort study aims to investigate the prevalence and clinical significance of head and neck arterial stenosis in patients with coronary artery disease (CAD) undergoing or scheduled for percutaneous…
- Conditions
- Coronary Artery Disease, Carotid Artery Stenosis, Cerebrovascular Disorders
- Trial name
- ANGEL-UNIFY (NCT07034157)
- Testing
- Percutaneous Coronary Intervention, Cerebrovascular Intervention (CAS ）, No Intervention / Observation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (AF), Pulsed Field Ablation
3D-Guided Pulsed Field Ablation for Paroxysmal AF
Atrial fibrillation (AF) is a common arrhythmia, especially in the elderly, and can lead to severe complications like stroke and heart failure.
- Trial name
- NCT07023237
- Testing
- pulsed field ablation
- Volunteers
- 430 people
- Sponsor
- Beijing Anzhen Hospital
Neuro-co-cardiological Diseases, Post-cardiac Surgery Cerebrovascular Diseases
Outcomes and Risk Factors of Different Treatment Strategies for Neuro-co-cardiological Diseases and Post-cardiac Surgery Cerebrovascular Diseases
The objective of this observational cohort study is to evaluate the clinical outcomes of various treatment strategies for cerebrovascular and cardiovascular diseases.
- Conditions
- Neuro-co-cardiological Diseases, Post-cardiac Surgery Cerebrovascular Diseases, Vascular Lesion
- Trial name
- NCT07012668
- Testing
- Interventional or surgical treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Anzhen Hospital
Aortic Dissection Type A, Transfusions
Use of PRP in Open Surgery for Type A Aortic Dissection
The goal of this clinical trial is to determine if autologous platelet rich plasma (PRP) can reduce the need for blood transfusions in patients undergoing open surgery for Type A aortic dissection.
- Conditions
- Aortic Dissection Type A, Transfusions, Platelet Rich Plasma (PRP), Organ Protection
- Trial name
- NCT07005661
- Testing
- Autologous Platelet Rich Plasma, Standard Blood Management
- Volunteers
- 250 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (AF)
Chinese Atrial Fibrillation Registry
This prospective, observational cohort study aims to establish a long-term registry of adult patients with atrial fibrillation (AF) in China to comprehensively characterize patient profiles and evaluate real-world management and…
- Trial name
- China-AF (NCT06987825)
- Where
- 2 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Beijing Anzhen Hospital
Heart Failure
Efficacy and Safety of Xinyue Capsule in the Treatment of Heart Failure With Preserved Ejection Fraction
The purpose of this study is to evaluate the effect of Xinyue Capsule in the improvement cardiac function and reduction the level of heart failure biomarker NT-proBNP in patients suffering from HF with an ejection fraction…
- Trial name
- NCT06946095
- Testing
- Chinese patent medicine
- Volunteers
- 246 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (AF), Aortic Arch Replacement
Cardiac Denervation in Aortic Arch Replacement
Atrial fibrillation (AF) is one of the most common clinical arrhythmias, particularly after cardiac surgery, where its incidence can reach as high as 10% to 40%, significantly impacting patients' prognosis.
- Trial name
- NCT06927908
- Testing
- Partial Cardiac Denervation
- Volunteers
- 570 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (AF)
Photoplethysmography (PPG) Algorithm with Smartwatch in Evaluation of Atrial Fibrillation Burden After Catheter Ablation
The purpose of this study is to evaluate the effectiveness of a smart electrocardiogram watch based on the PPG algorithm in monitoring the atrial fibrillation burden of patients after catheter ablation.
- Trial name
- Polaris-AFCA (NCT06842160)
- Testing
- intervention group
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Anzhen Hospital
Congenital Heart Disease (CHD), Artificial Intelligence (AI)
A Multicenter Study of Artificial Intelligence Model for Fetal Congenital Heart Disease
This study addresses congenital heart disease in fetuses, a specific birth defect, by collaborating with multicenter medical institutions across China.
- Trial name
- NCT06796127
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Persistent Atrial Fibrillation, Radiofrequency Catheter Ablation
Pulsed Field Ablation Versus Radiofrequency Ablation for Persistent Atrial Fibrillation
This clinical trial aims to compare the efficacy and safety of pulsed field ablation and radiofrequency ablation to treat persistent atrial fibrillation in adults.
- Conditions
- Persistent Atrial Fibrillation, Radiofrequency Catheter Ablation, Pulsed Field Ablation
- Trial name
- PRAISE (NCT06791629)
- Testing
- Pulsed Field Ablation, Radiofrequency Ablation
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Beijing Anzhen Hospital
Congenital Heart Disease, Coarctation of Aorta
An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease
The purpose of this two-way cohort study was to explore whether an integrated prenatal and postnatal treatment model for neonates with critical congenital heart disease (CCHD) could be effective in avoiding preoperative…
- Conditions
- Congenital Heart Disease, Coarctation of Aorta, Aortic Stenosis, Pulmonary Atresia
- Trial name
- NCT06768008
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Anzhen Hospital
ST-elevation Myocardial Infarction (STEMI)
Low-dose Evaluation of Aspirin After STEMI Patients With PCI: A Multicenter, Double-blind, Randomized Controlled Clinical Trial
The study aims to optimize the dual antiplatelet therapy regimen for patients with STEMI after PCI, focusing on addressing the following key technical challenges: establishing an effectiveness evaluation system for a low-dose…
- Trial name
- LEAST (NCT06756945)
- Testing
- aspirin 100 mg once daily (two 50 mg aspirin tablets) plus ticagrelor 90 mg twice daily
- Volunteers
- 3,612 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation
A Study on the Effectiveness of the Application of an Artificial Intelligence Algorithm for Calibrating PPG With ECG to Improve the Accuracy of Atrial Fibrillation Burden Estimation
Use the ECG watch to collect W-PPG and W-ECG data. Through artificial intelligence algorithms, compare the W-PPG data collected by the ECG watch and the W-PPG data calibrated by the W-ECG data of the ECG watch with the P-ECG data…
- Trial name
- EASE-AF (NCT06552468)
- Testing
- AF monitoring by a smartwatch with PPG
- Where
- China
- Volunteers
- 1,054 people
- Sponsor
- Beijing Anzhen Hospital
Invasive Fungal Infections, Liposomal Amphotericin B
Population Pharmacokinetics of L-AmB in Chinese Patients Assisted by Extracorporeal Membrane Pulmonary Oxygenation (ECMO)
The goal of this study is to investigate the effects of ECMO-assisted therapy on L-AmB PK parameters in patients with critically ill patients of invasive fungal infections, and to determine the in vivo pharmacokinetic changes of…
- Trial name
- NCT06754436
- Testing
- Determination of blood drug concentration
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Anzhen Hospital
Actue Coronary Syndrome
Clinical Features and Linked mEchanisms in Acute Risk-free AMI
This study aims to investigate the clinical characteristics and underlying mechanisms of acute myocardial infarction (AMI) in patients without traditional cardiovascular risk factors, such as hypertension, diabetes, dyslipidemia…
- Trial name
- CLEAR-AMI (NCT06716177)
- Volunteers
- 300 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (AF)
Photoplethysmography (PPG) Algorithm With Smartwatch in Evaluation of Atrial Fibrillation Burden
The purpose of this study is to evaluate the monitoring effect of a smart electrocardiogram watch based on the PPG algorithm on atrial fibrillation burden.
- Trial name
- Polaris-AF (NCT06686940)
- Testing
- intervention group
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Anzhen Hospital
Acute Coronary Syndrome, Unstable Angina
Treatment of ACuTe Coronary Syndromes With Low-dose colchICine
This trial is designed to evaluate whether low-dose colchicine, in addition to standard treatment recommended by guidelines, further reduces the risk of major adverse cardiovascular events in patients with acute coronary…
- Conditions
- Acute Coronary Syndrome, Unstable Angina, ST Elevation Myocardial Infarction, Non ST Segment Elevation Myocardial Infarction
- Trial name
- NCT06215989
- Testing
- Colchicine Pill
- Where
- China
- Volunteers
- 6,574 people
- Sponsor
- Beijing Anzhen Hospital
Right Heart Insufficiency, Tricuspid Regurgitation
Application of FAPI Visualization in the Assessment of Right Ventricular Dysfunction Due to Volume Overload
\"Bicuspid aortic stenosis represents the most prevalent form of cardiac valve disease, primarily resulting from degenerative alterations and rheumatic conditions that disrupt mitral valve function.
- Trial name
- NCT06663566
- Testing
- Diagnose the patients right heart function as well as right heart fibrosis, Diagnose the patient's right heart function as well as right heart fibrosis
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Anzhen Hospital
Supraventricular Tachycardia (SVT)
A Novel Valsalva Assist Device for Terminating Supraventricular Tachycardia
The goal of this clinical trial is to evaluate the efficiency of a device for terminating supraventricular tachycardia. The main questions it aims to answer are: The Valsalva manoeuvre is a first-line treatment for…
- Trial name
- NCT06622772
- Testing
- Valsalva assist device, standard Valsalva manoeuvre
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Beijing Anzhen Hospital
Heart Failure
Outcomes of a Novel Magnetically Levitated LVAD: a Multicenter Analysis
This multicenter, retrospective cohort study evaluates the clinical outcomes associated with a novel fully magnetically levitated left ventricular assist device (LVAD) in patients with advanced heart failure.
- Trial name
- NCT06596499
- Testing
- CH-VAD
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Beijing Anzhen Hospital