Clinical trials: sponsored by Beijing Anzhen Hospital
Comorbidities and Coexisting Conditions, Old Age; Debility
Clinical and Biological Sample Database of Chinese Elderly Patients With Multiple Diseases
The investigators aim to establish a clinical database and biobank for elderly patients with multiple diseases. The collected data will include demographic information, comorbidity characteristic, FRAIL scale, age-adjusted…
- Trial name
- NCT05797402
- Where
- China
- Volunteers
- 10,000,000 people
- Sponsor
- Beijing Anzhen Hospital
Mild Cognitive Impairment, Hypertension
Computerized Cognitive Training to Protect Cognitive Function Among Hypertension Patients
Hypertension is an risk factor for cognitive impairment. The primary objective of this study is to evaluate the efficacy of 12-week computerized cognitive training in people with hypertension and mild cognitive impairment.
- Trial name
- NCT05704270
- Testing
- Multi-domain adaptive cognitive training, Basic cognitive training with no difficulty change
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation, Atrial Fibrillation Paroxysmal
Study on the Effectiveness of AF Analysis Software in AF Rhythm Monitoring
Atrial fibrillation (AF) is a serious public health problem because of its increasing incidence and prevalence in the aging population.
- Trial name
- PPG-AF (NCT05333380)
- Testing
- ECG/PPG monitoring
- Where
- 2 sites in China
- Volunteers
- 266 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Prospective Registry of the Current Status of Care for Patients With Coronary Artery Disease
The study will estimate the current status of care for participants with coronary artery disease
- Trial name
- NCT05337319
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation
Henagliflozin in Patients With Atrial Fibrillation
The HENA-AF trial will evaluate the effects of henagliflozin on cardiac structure, function, and biomarkers of HF in patients with AF.
- Trial name
- HENA-AF (NCT05252624)
- Testing
- Henagliflozin 5Mg Tab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
CompArison of PCI in NaTive Arteries Versus ByPAss Grafts In PatieNts With Prior CABG (CAPTAIN)
Coronary atherosclerotic heart disease (CAD) has been considered the leading cause of death in both developed and developing countries.
- Trial name
- NCT05368597
- Testing
- PCI in native vessel or in bypass graft
- Where
- China
- Volunteers
- 1,491 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease, Diabete Mellitus
The Efficacy of SGLT-2 Inhibitor in Patients With CAD and DM Undergoing PCI.
The study is to compare the effects of SGLT-2 inhibitors and other oral hypoglycemic agents in patients with coronary heart disease and diabetes mellitus undergoing percutaneous coronary intervention.
- Trial name
- NCT05333159
- Testing
- SGLT2 inhibitor
- Where
- China
- Volunteers
- 1,424 people
- Sponsor
- Beijing Anzhen Hospital
Acute Coronary Syndrome
Bleeding Risk Assessment System for Antithrombotic Therapy of ACS
Antithrombotic therapy is the cornerstone of the management of patients with acute coronary syndrome (ACS), which result in lower risk of mortality and ischemic events.
- Trial name
- NCT04162808
- Where
- China
- Volunteers
- 6,379 people
- Sponsor
- Beijing Anzhen Hospital
Elderly Patients, Coronary Heart Disease
Registry Study of Pharmacotherapy and Clinical Outcomes in Elderly Patients With Coronary Heart Disease (PHARM-ageing)
A registry study on drug therapy and clinical outcomes in elderly patients with coronary heart disease
- Conditions
- Elderly Patients, Coronary Heart Disease, Drug Therapy, Clinical Outcomes
- Trial name
- NCT05246722
- Volunteers
- 15,000 people
- Sponsor
- Beijing Anzhen Hospital
ST-elevation Myocardial Infarction, Multivessel Coronary Disease
Timing of Complete Revascularization in Patients With ST-segment Elevation Myocardial Infarction And Multivessel Disease
At present, the two treatment strategies of opening non infarct related arteries (non IRA) simultaneously or by stages after emergency percutaneous coronary intervention (PCI) in patients with acute ST segment elevation…
- Trial name
- TERMINAL (NCT05231226)
- Testing
- Immediately CR, Staged (within 45 days) CR
- Where
- China
- Volunteers
- 426 people
- Sponsor
- Beijing Anzhen Hospital
Valvular Surgery
Relationship Between Postoperative Delirium and Heart Function in Valvular Surgery
Delirium is an acute brain lesion characterized by abnormalities of consciousness, attention, cognition and sensation. Many brain diseases such as stroke, traumatic brain injury and intracranial hypertension can lead to cardiac…
- Trial name
- NCT05211934
- Testing
- No intervention
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Heart Disease (CHD), Renal Insufficiency
The Effect of TaiChi on Ischemic Burden of Patients With Coronary Heart Disease Complicated With Renal Insufficiency
This study focuses on patients with incomplete revascularization combined with renal insufficiency. And since heart and kidney are two organs influence each other, the study take the mechanism of heart and kidney comorbidity and…
- Trial name
- NCT05178602
- Testing
- Tai Chi Intervention Group
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Beijing Anzhen Hospital
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Real-world Experience of Catheter Ablation Using Novel Ablation Technologies for the Treatment of Atrial Fibrillation
The primary purpose of this registry is to obtain real-world clinical experience for the latest and future ablation technologies when used in conjunction with the Carto system in the treatment of patients with atrial fibrillation…
- Trial name
- NOVEL AF (NCT05006456)
- Testing
- Catheter ablation
- Volunteers
- 4,000 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Intraoperative Hemodynamics in CABG
The study is to determine the effects of the intraoperative hemodynamics in patients undergoing coronary artery bypass graft on the short-term and long-term outcomes.
- Trial name
- NCT05125315
- Volunteers
- 300 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Effects of Different Revascularization StrateGies in Complex Coronary Artery DiseasE (EDGE)
Coronary heart disease is one of the most serious diseases that endanger people's health. Complex coronary artery disease is critical and has high mortality.
- Trial name
- NCT05121610
- Testing
- The procedures include PCI, CABG and HCR
- Volunteers
- 2,864 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
SAfety and EFficacy of Bridging Antithrombotic Therapy During Elective Non-cardiac Surgery
Patients with coronary artery disease, especially after PCI, require long-term oral antiplatelet therapy. However, this patient population may inevitably require non-cardiac surgery for a variety of conditions.
- Trial name
- SAFE (NCT04675801)
- Where
- China
- Volunteers
- 950 people
- Sponsor
- Beijing Anzhen Hospital
Myocardial Infarction
Randomized Evaluation of Shenfu Injection to Reduce Myocardial Injury
This study aims to evaluate whether perioperative use of Shenfu Injection, as compared to placebo, could reduce infarct size assessed by cardiac magnetic resonance (CMR) in patients with acute anterior ST-segment elevation…
- Trial name
- RESTORE (NCT04493840)
- Testing
- Shenfu Injection, 5% Glucose Injection
- Where
- China
- Volunteers
- 326 people
- Sponsor
- Beijing Anzhen Hospital
Microcirculation, Fluid Therapy
Effects of Fluid Therapy on Microcirculatory Reactivity
Through preoperative fluid therapy, to investigate whether it can alleviate the microcirculation dysfunction after induction of anesthesia, and reduce the incidence of perioperative fluid therapy-related complications, thereby…
- Trial name
- NCT04982016
- Testing
- crystal therapy, colloid therapy
- Volunteers
- 126 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease, Myocardial Ischemia
Evaluation of Accuracy of CFD-based RuiXin-FFR by Comparing With Pressure-wire-based FFR
Coronary Artery Disease (CAD) is the top killer nowadays. Pressure-wire-based Fractional Flow Reserve (FFR) is the gold standard for measuring ischemia in coronary arteries.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Myocardial Fractional Flow Reserve
- Trial name
- NCT04731285
- Testing
- Pressure wire fractional flow reserve, CFD-based RuiXin-FFR
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease, Obstructive Sleep Apnea of Adult
Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is an increasingly common chronic disorder in adults. Compared to the general population, OSA occurs more often in patients with coronary artery disease (CAD), with a reported prevalence of 38% to…
- Trial name
- VISION (NCT04022824)
- Testing
- OSA, Non-OSA
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Beijing Anzhen Hospital