Clinical trials: sponsored by Beijing Friendship Hospital
Autoimmune Hepatitis
A Study on Factors of Biochemical Response in Autoimmune Hepatitis
The goal of this observational study is to clarify the clinical characteristics of autoimmune hepatitis (AIH) in China. The main questions it aims to answer are: Human leukocyte antigen (HLA) gene susceptibility in Chinese AIH…
- Trial name
- NCT06356506
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Beijing Friendship Hospital
Lung Cancer, Breast Cancer
Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis
The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches.
- Conditions
- Lung Cancer, Breast Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT06363123
- Where
- 4 sites in China
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
HLH
Zanubrutinib for HLH
This study is a prospective single-arm clinical study, focusing on Hemophagocytic lymphohistocytosis，to evaluate the clinical efficacy and safety of zanubrutinib.
- Trial name
- NCT05320575
- Testing
- Zanubrutinib
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Beijing Friendship Hospital
Cardiovascular Diseases, Percutaneous Coronary Intervention
PCI in Beijing Friendship Hospital
The goal of this study is to discover the potential risk factors related percutaneous coronary intervention. It aims to stratify the risk of PCI patients and discover the prognostic value of these risk fators.
- Trial name
- BF-PCI (NCT05728580)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Friendship Hospital
Coronary Artery Disease, Hypertension
China Elderly Comorbidity Medical Database
The objective of this observational cohort study is to provide comprehensive evaluation and early warning for elderly patients with chronic diseases.
- Conditions
- Coronary Artery Disease, Hypertension, Diabetes Mellitus, Osteoporosis
- Trial name
- CECMed (NCT06316544)
- Where
- China
- Volunteers
- 4,100 people
- Sponsor
- Beijing Friendship Hospital
Locally Advanced Rectal Cancer
Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer
This is a multicenter, prospective, randomized controlled study to evaluate the effectiveness and safety of neoadjuvant chemoradiotherapy combined with PD-1 inhibitor and PCSK9 inhibitor in the treatment of patients with pMMR/MSS…
- Trial name
- NCT06304987
- Testing
- Long-course chemoradiation and PD-1 inhibitor, with PCSK9 inhibitor, Long-course chemoradiation and PD-1 inhibitor, without PCSK9 inhibitor
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Beijing Friendship Hospital
Duodenal Adenoma, Complication of Treatment
Effectiveness of Endoscopic Papillectomy With Stent for Treating Duodenal Papillary Adenoma
This is a retrospective study, including 79 patients with duodenal papillary adenoma, who treated with Endoscopic Papillectomy (EP) at Beijing friendship hospital.
- Trial name
- NCT06301048
- Testing
- Stent Placement in Pancreatic and Bile Ducts
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Beijing Friendship Hospital
Gastric Cancer, Esophagus Cancer
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis
This study constitutes a case-control investigation employing a retrospective approach. Plasma samples from individuals with esophageal cancer, benign esophageal diseases, gastric cancer, benign gastric diseases, and a healthy…
- Trial name
- NCT06278064
- Testing
- Gastric Cancer, Esophagus Cancer
- Where
- 3 sites in China
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Mild Cognitive Impairment, Idiopathic Membranous Nephropathy
the Effects of Different Treatment Schemes on Cognitive Function of Patients With Idiopathic Membranous Nephropathy
This study intends to apply prospective, open, single-center, randomized controlled study to evaluate the cognitive status of patients with Idiopathic membranous nephropathy and the influence of different treatment schemes on the…
- Trial name
- NCT06245707
- Testing
- prednisone,methylprednisone and cyclophosphamide, Rituximab
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Beijing Friendship Hospital
Biliary Tract Cancer, Anti-PD-1 Therapy
Camrelizumab Combined With Apatinib and Capecitabine in Patients With Advanced Biliary Tract Cancer.
Biliary tract cancer (BTC) is a series of rare malignancies with poor overall prognosis. Radical surgery the preferred treatment option, but most patients have lost the opportunity of surgery at the time of diagnosis.
- Conditions
- Biliary Tract Cancer, Anti-PD-1 Therapy, Targeted Molecular Therapy, Capecitabine
- Trial name
- NCT04720131
- Testing
- Camrelizumab, apatinib, Capecitabine
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Beijing Friendship Hospital
Papillary Thyroid Carcinoma, Thermal Ablation
A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid Carcinoma
A prospective cohort of papillary thyroid carcinoma(PTC), patients who received thermal ablation in our hospital since February 2023 was established as the study object.
- Trial name
- NCT05962892
- Testing
- No Intervention
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Friendship Hospital
Clarify the Difference of Short-term Infection Rate Between Diffrent Catheter
Comparison of Short-term Application of Dialysis Catheter With Tunnel-cuffed Catheter Versus Non-ccuffed Catheter: a Multicenter Prospective Cohort Study
Through a multi-center, prospective cohort study, hemodialysis patients with right internal jugular vein catheterization were collected and divided into tunnel-cuffed catheter group and non-cuffed catheter group according to the…
- Trial name
- NCT06206447
- Testing
- Tunnel-cuffed Catheter, Non-ccuffed Catheter
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Locally Advanced Rectal Cancer
Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer
This is a phase II/III, multi-center, open-label, 3-arm, randomized controlled trial assessing the efficacy and safety of neoadjuvant long-course chemoradiation combined with Tislelizumab (PD-1 inhibitor) and subsequent TME…
- Trial name
- NCT05245474
- Testing
- Long-course chemoradiation, with or without Tislelizumab (PD-1 inhibitor)
- Where
- 8 sites in China
- Volunteers
- 186 people
- Sponsor
- Beijing Friendship Hospital
Invasive Breast Cancer, Cavitation
Effect of Ultrasound Combined With Microbubbles on Blood Perfusion in Invasive Breast Cancer
Blood perfusion insufficiency and hypoxia are the main causes of drug resistance to chemotherapy in breast cancer. Increasing blood perfusion can improve drug delivery.
- Conditions
- Invasive Breast Cancer, Cavitation, Perfusion
- Trial name
- NCT06158217
- Testing
- ultrasound combined with microbubbles
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Friendship Hospital
Colon Cancer
Intracorporeal Versus Extracorporeal Anastomotic After Laparoscopic Right Colectomy
Background: Laparoscopic assisted right hemicolectomy is recommended for right colon cancer. As a more minimally invasive procedure, intracorporeal ileocolic anastomosis has potential advantages: reducing torsion and traction on…
- Trial name
- NCT05493033
- Testing
- Intracorporeal anastomotic after LRC, Extracorporeal anastomotic after LRC
- Volunteers
- 1,158 people
- Sponsor
- Beijing Friendship Hospital
Hemophagocytic Lymphohistiocytosis, Epstein-Barr Virus
Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement
EBV-HLH is a rare disease with high mortality, especially for those with intestinal involvement. In order to reduce disease burden and improve survival of these patients, we conduct a prospective observational study to explore…
- Conditions
- Hemophagocytic Lymphohistiocytosis, Epstein-Barr Virus, Bowel Resection
- Trial name
- NCT06131489
- Testing
- Segmental bowel resection combined with the DEP regimen
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
HLH
Teniposide Incorporating Bu/Cy Conditioning Regimen for HLH With Central Nervous System Involvemen
Hemophagocytic lymphohistiocytosis (HLH) is a highly inflammatory disease involving cytokine storms and is characterised by rapid progression and high mortality.
- Trial name
- NCT06048107
- Testing
- Teniposide
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Anesthesia
Comparison of the Effects of Esketamine, Sufentanil, or Lidocaine on Tussis Reflection During Upper Gastroscopy
the frequency of tussis, nausea and vomiting, and/or body movements observed at the insertion of the endoscope into the pharyngeal cavity or within 5 min of endoscope insertion.
- Trial name
- NCT05497492
- Testing
- propofol, propofol and sufentanil, propofol and esketamine
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Refractory, Recurrence
GTP Regimen in the Treatment of Refractory/Recurrent HLH
The goal of this clinical trial is to learn about efficacy and safety of GTP regimen in refractory/recurrent hemophagocytic lymphohistiocytosis.
- Conditions
- Refractory, Recurrence, Hemophagocytic Lymphohistiocytosis
- Trial name
- NCT06038422
- Testing
- GTP regimen
- Volunteers
- 15 people
- Sponsor
- Beijing Friendship Hospital
Chronic Hepatitis B Patients
Dynamic Changes of Serum HBV RNA in Chronic Hepatitis B Patients
Some patients with low-level viremia (LLV) are also likely to develop hepatocellular carcinoma (HCC) or other liver diseases. The relationship between HBV RNA levels and fibrosis in patients with HBV DNA negative or LLV is still…
- Trial name
- NCT05991531
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Friendship Hospital