Clinical trials: sponsored by Beijing Friendship Hospital
STEMI
Metabolic Characteristics of Type 2 Diabetes Mellitus Combined With Acute Myocardial Infarction: A Untargeted Metabolomics Study
This study is a retrospective case-control study. In this study, through untargeted metabolomics, investigators identified several specific changed serum metabolites in T2DM patients with or without AMI and their…
- Trial name
- NCT05601310
- Testing
- liquid chromatography-mass spectrometry (LC/MS) analysis
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Beijing Friendship Hospital
Brain Diseases, Hypertension
Clinical Indicators and Brain Image Data: a Study Based on Kailuan Cohort
The investigators will analyze the relationship between the medical history, physiological indicators and the cerebral small vessel disease as well as the structural and functional changes of the brain/head and neck organs in a…
- Trial name
- NCT05453877
- Testing
- No intervention will be applied.
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Endometrial Neoplasms
Endometrial Lesions Predictions
To explore the risk factors of endometrial lesions in patients with abnormal uterine bleeding and establish prediction models which can discriminate between different endometrial etiologies of abnormal uterine bleeding(AUB).
- Trial name
- NCT05588076
- Testing
- no intervention
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Beijing Friendship Hospital
Non-Alcoholic Fatty Liver Disease
BeijngFH Health Cohort Study
Metabolic associated fatty liver disease(MEFLD) is a major chronic liver disease that can lead to various adverse events, such as liver cancer, cardiovascular disease, and chronic kidney disease.
- Trial name
- FHCS (NCT05546086)
- Where
- China
- Volunteers
- 8,103 people
- Sponsor
- Beijing Friendship Hospital
Hemophagocytic Lymphohistiocytosis
Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLH
This study aimed to investigate the efficacy and safety of venetoclax combined with dexamethasone and etoposide as a salvage therapy for hemophagocytic lymphohistiocytosis.
- Trial name
- NCT05546060
- Testing
- Venetoclax, Dexamethasone, Etoposide
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Carotid Artery Diseases, Carotid Artery Stenosis
Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization
The majority (>80%) of strokes are of ischemic etiology, of which ≈15% to 20% are attributable to atherosclerosis of the extracranial carotid arteries.
- Conditions
- Carotid Artery Diseases, Carotid Artery Stenosis, Cerebrovascular; Disorder, Arteriosclerotic, Cardiovascular Diseases
- Trial name
- HALO (NCT05539781)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Hearing Loss, Tinnitus
Establishment and Application of a New Imaging System for Otology Based on Ultra-high Resolution CT
Tinnitus, hearing loss and vertigo are the three major diseases of otology, affecting hundreds of millions of people in our country, and are major health problems.
- Conditions
- Hearing Loss, Tinnitus, Vertigo
- Trial name
- NCT05533840
- Testing
- ultra-high-resolution computed tomography exams
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Chronic Hepatitis b
Prediction System of Clinical Endpoint Events for Chronic Hepatitis B Patients
A total of 2000 chronic hepatitis B (CHB) patients with liver biopsy performed at least 1 year after antiviral therapy are enrolled. All the patients will receive original antiviral treatment for the following 10 years.
- Trial name
- NCT03777969
- Where
- 7 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Friendship Hospital
Unresectable Metastatic Colorectal Cancer
A Phase II Study of Fruquintinib Combined With Capecitabine as First-line Treatment for Advanced Metastatic Colorectal Cancer Unsuitable for Intravenous Chemotherapy
This is a single center, open-labeled, single arm phase II study aimed to investigate the efficacy and safety of fruquintinib combined with capecitabine as first-line treatment for advanced metastatic colorectal cancer patients…
- Trial name
- NCT04866108
- Testing
- fruquintinib plus capecitabine
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Beijing Friendship Hospital
Colonic Cancer, Rectal Cancer
Chinese Colorectal Cancer Database
1. To establish the Chinese people's own clinical data database of colorectal cancer, reflecting the law and characteristics of colorectal cancer patients in China. 2.
- Conditions
- Colonic Cancer, Rectal Cancer, Prospective Studies
- Trial name
- CCCD (NCT05434026)
- Where
- China
- Volunteers
- 200,000 people
- Sponsor
- Beijing Friendship Hospital
Type2 Diabetes, Complication of Bariatric Procedure
Efficacy and Safety of One-anastomosis Versus Roux-en-Y Gastric Bypass for Type 2 Diabetes Remission
Diabetes mellitus (T2DM) is the most common complication of obesity patients. According to previous literature reports, weight loss and metabolic surgery are powerful means to treat obesity complicated with T2DM.
- Trial name
- ORDER (NCT05015283)
- Testing
- The laparoscopic One-anastomosis gastric bypass will consist of:, The laparoscopic Roux-en-Y gastric bypass will consist of:
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Beijing Friendship Hospital
Langerhans Cell Histiocytosis
Safety and Efficacy of CD207 Targeted CAR-T Cell Therapy in Patients With R/R Langerhans Cell Histiocytosis
This is a single-arm study to evaluate the efficacy and safety of CD207 targeted CAR-T cell therapy in relapsed and refractory langerhans cell histiocytosis.
- Trial name
- NCT05477446
- Testing
- CD207 CAR-T cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Beijing Friendship Hospital
Early Childhood Caries
Clinical Analysis of a Risk-graded and Comprehensive Intervention for Early-childhood-caries
Cariogram and Cariostat will be used to assess the risk of caries in kindergarten children aged 3 years. Routine preventive measures will be taken for children at low risk of caries, and intensive intervention measures will be…
- Trial name
- NCT05260216
- Testing
- Comprehensive prevention and treatment, Routine prevention
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Right Hemicolectomy, Colon Cancer
The China Laparoscopic Right Hemicolectomy SNAPSHOT
The main objective is to explore the current practice of right hemicolectomy for colon cancer located in the ascending colon and hepatic flexure in selected Chinese high quality and high volume centres.
- Trial name
- NCT04628182
- Where
- China
- Volunteers
- 1,579 people
- Sponsor
- Beijing Friendship Hospital
Secondary Hemophagocytic Lymphohistiocytosis, Chronic Active Epstein-Barr Virus Infection
Rituximab Monotherapy for EBV-HLH and CAEBV
This study is a prospective single-arm clinical study, focusing on Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis and Chronic Active Epstein-Barr Virus Infection with only and mainly B lymphocytes of EBV…
- Trial name
- NCT05384743
- Testing
- Rituximab Monotherapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Friendship Hospital
STEMI
Relationship Between Level of GPCR Autoantibodies and Cardiac Structure & Funtions Based on UCG and CMR
This study is a prospective cohort study，we want to observe the changes of different cardiovascular antibody levels in STEMI patients undergoing emergency PCI;and combined with different cardiovascular antibody levels and various…
- Trial name
- NCT05368584
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Beijing Friendship Hospital
Colorectal Neoplasms
Multi-omics Model Predicts Efficacy of Preoperative Neoadjuvant Chemoradiotherapy Combined PD-1 Antibody Therapy for Locally Advanced Rectal Cancer
The purpose of this clinical research is to establish a multi-omics model based on genomics，transcriptomics，gut microbiota in predicting pathologic response after neoadjuvant chemoradiotherapy combined PD-1 antibody given to…
- Trial name
- NCT05368051
- Testing
- long course radiotherapy + capecitabine + PD-1 monoclonal antibody
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Friendship Hospital
CAEBV
Selinexol Combined With Dexamethasone in the Treatment of CAEBV
This study is a single-center, prospective, observational clinical study to evaluate the Effecive and Safty of Selinexol and Dexamethasone in CAEBV
- Trial name
- NCT05347381
- Testing
- Selinexol and Dexamethasone
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Beijing Friendship Hospital
Hemophagocytic Lymphohistiocytosis
L-DEP/DEP Regimen and PD-1 Antibody as a Treatment for Relapse/Refractory EBV-HLH
This study aimed to investigate the efficacy and safety of L-DEP (L-Asparaginasum, liposomal doxorubicin, etoposide and methylprednisolone) together with PD-1 antibody as an treatment for relapse/refractory EBV associated…
- Trial name
- NCT05315336
- Testing
- L-DEP and PD-1 antibody
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Friendship Hospital
Preoperative Sleep Disorder, Preoperative Anxiety
Relationship Between Perioperative Related Factors and Inflammatory Markers and Postoperative Delirium in Elderly Patients With Non-cardiac Major Surgery
Perioperative neurocognitive impairment, including postoperative delirium (POD), is common in older patients after anesthesia and surgery and is associated with poorer short- and long-term outcomes, including worsening cognitive…
- Conditions
- Preoperative Sleep Disorder, Preoperative Anxiety, Inflammatory Reaction, Postoperative Delirium
- Trial name
- NCT05341531
- Testing
- elderly patients undergoing non-cardiac surgery
- Volunteers
- 400 people
- Sponsor
- Beijing Friendship Hospital