Clinical trials: sponsored by Beijing Friendship Hospital
Hemodialysis, Diabetes
Analysis of Influencing Factors of Hypotension in Diabetic Patients Undergoing Dialysis
Hypotension (IDH) during dialysis is a common complication in hemodialysis, and the incidence is 20-50% in hemodialysis patients, the proportion of diabetic patients with IDH is 26.7%, which is much higher than that of…
- Trial name
- NCT05325892
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Friendship Hospital
All Diseases That Require Gastrointestinal Open Surgery
Subcutaneous Closed-Suction Drainage Affects Surgical Wounds Healing in Lower Gastrointestinal Open Surgery: a Randomized Controlled Study
This is a single-center, randomized controlled trial to evaluate whether subcutaneous closed-suction drainage would decrease the incidence of poor surgical site healing in lower gastrointestinal open surgery.
- Trial name
- NCT05318430
- Testing
- Subcutaneous closed-suction drainage device
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Beijing Friendship Hospital
EBV Infection
Study on the Application of Saliva EBV-DNA Detection in EBV Infection Related Diseases
This study is a single-center, prospective, observational clinical study to evaluate the Application of saliva EBV-DNA Detection in EBV Infection Related Diseases
- Trial name
- NCT04782674
- Testing
- Saliva Testing
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Friendship Hospital
Macrophage Activation Syndrome
Ruxolitinib and Methylprednisolone as a First-line Treatment for Macrophage Activation Syndrome
The present study was a single-center, prospective, non-comparative in which macrophage activation syndrome patients were selected as the main subjects to evaluate the effect and safety of Ruxolitinib and methylprednisolone…
- Trial name
- NCT05137496
- Testing
- Ruxolitinib, methylprednisolone
- Volunteers
- 40 people
- Sponsor
- Beijing Friendship Hospital
Hemophagocytic Lymphohistiocytosis
DEP Combine With PD-1 Antibody as an Treatment for EBV-HLH
This study aimed to investigate the efficacy and safety of DEP (liposomal doxorubicin, etoposide and methylprednisolone) together with PD-1 antibody as an treatment for EBV associated hemophagocytic lymphohistiocytosis.
- Trial name
- NCT05164978
- Testing
- DEP combine with PD-1 antibody
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
PTLD, CAEBV
Low-dose CD20 Monoclonal Antibody Injection in Preemptive Treatment of PTLD in Patients With EBV-HLH/CAEBV
This is a clinical study on the efficacy and safety of low-dose CD20 monoclonal antibody injection in preemptive treatment of EBV positive lymphoproliferative diseases after allo-HSCT in patients with EBV-HLH and CAEBV
- Conditions
- PTLD, CAEBV, HLH
- Trial name
- NCT05258136
- Testing
- low-dose CD20 monoclonal antibody injection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Colorectal Neoplasms
Neoadjuvant Chemoradiotherapy Plus Tislelizumab Followed by TME for LARC.
Long course radiotherapy plus neoadjuvant chemotherapy followed by resection total mesorecta excision has accepted widespread recognized in the treatment of locally advanced rectal cancer (LARC).
- Trial name
- NCT04911517
- Testing
- long course radiotherapy + capecitabine + PD-1 monoclonal antibody treatment combinations
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Friendship Hospital
Efficacy
Multitarget Therapy for Idiopathic Membranous Nephropathy
Membranous nephropathy (MN) is one of the commonest causes of nephrotic syndrome in adults, idiopathic membranous nephropathy (IMN) accounts for 70%-80% of all MN patients. There is no standard specific treatment for IMN.
- Trial name
- MTIMN (NCT04424862)
- Testing
- Prednisone, ciclosporin and mycophenolate mofetil, Ponticelli Regimen
- Where
- 2 sites in China
- Volunteers
- 82 people
- Sponsor
- Beijing Friendship Hospital
EBV Infection
PD1 Antibody and Lenalidomide as a Treatment for EBV-HLH or CAEBV
The present study was a prospective one-arm clinical study, in which EBV-HLH/chronic active EBV infection patients were selected as the main subjects to evaluate the effect of PD-1 antibody and lenalidomide regimens on ebv-dna…
- Trial name
- NCT04084626
- Testing
- PD1 antibody, lenalidomide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Friendship Hospital
Dream, General Anesthesia
Factors Associated With Quality of Dreams During General Anesthesia
Patients frequently report having dreams during general anesthesia. The incidence of dreams during general anesthesia that have been reported by patients upon awakening has been reported to range from 10 to 36% [1] and to be…
- Conditions
- Dream, General Anesthesia, Perioperative Factors, Depression
- Trial name
- NCT05179590
- Testing
- Quality of Dream
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Kidney Failure, Chronic, Cognitive Dysfunction
Emotion and Cognitive Function and Brain Imaging Change in HD Patients
1. Observe the influence of entering hemodialysis treatment on the emotional and cognitive functions of ESRD patients. 2. Observe the influence of entering hemodialysis treatment on the brain structure imaging of ESRD patients.
- Conditions
- Kidney Failure, Chronic, Cognitive Dysfunction, Magnetic Resonance Imaging
- Trial name
- NCT05137470
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Chidamide, Hemophagocytic Lymphohistiocytosis
Chidamide Combines With VP-16 and Methylprednisolone in the Treatment of HLH
Chidamide combines with VP-16 and methylprednisolone in HLH
- Trial name
- NCT05137522
- Testing
- Chidamide combines with VP-16 and methylprednisolone
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Liver Cirrhosis, Hepatitis B
Prevention of HCC Using Mobile Phone Applications
This prospective cohort study is initiated to evaluate the compliance improvement to the standardized follow-up and clinical management in the population of compensatory hepatitis B cirrhosis with a mobile health application…
- Trial name
- NCT05094869
- Testing
- Use of mobile health application, Online interaction, Self follow-up reminders
- Volunteers
- 8,000 people
- Sponsor
- Beijing Friendship Hospital
Hepatitis B, Decompensated Cirrhosis
Re-compensation and Its Clinical Characteristics in HBV Decompensated Cirrhosis
In this study, treatment-naïve HBV-related cirrhosis patients were retrospectively enrolled at the first episode of decompensation (ascites or variceal hemorrhage).
- Trial name
- NCT05086536
- Testing
- no intervention
- Where
- 7 sites in China
- Volunteers
- 600 people
- Sponsor
- Beijing Friendship Hospital
Hernia, Stoma Colostomy
Incidence and Risk Factors of Parastomal Hernia in Patients With Permanent Colostomy in China
Parastomal hernia refers to the protrusion of the area around the stoma or the ectopic protrusion of abdominal contents from the stoma (colostomy, ileostomy, ileostomy for bladder) in the abdominal wall defect.
- Trial name
- NCT05061589
- Testing
- permanent colostomy
- Where
- 2 sites in China
- Volunteers
- 712 people
- Sponsor
- Beijing Friendship Hospital
Liver Cirrhosis, Portal Hypertension
Extension Study of Carvedilol RCT Study
Patients who have completed 2-years treatment in RCT Study of carvedilol will receive another 2-years extension therapy, aiming to investigate the long-term efficacy of carvedilol for the prevention of esophageal varices in…
- Trial name
- NCT05021406
- Testing
- Carvedilol 12.5 MG
- Where
- 14 sites in China
- Volunteers
- 240 people
- Sponsor
- Beijing Friendship Hospital
PD-1, EBV Infection
PD-1 Antibody for Reactive EBV After BMT
PD-1 antibody for reactivation of EBV after transplantation in patients with CAEBV/EBV-HLH
- Conditions
- PD-1, EBV Infection, Transplant
- Trial name
- NCT04690036
- Testing
- toripalimab injection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
PD-1 Antibody, Mixed Chimerism
PD-1 Antibody Improve Mixed Chimerism
PD-1/PD-L1 pathway play an important role in Inhibiting the function of antigen-specific CD8+T cells, thus matter a lot in immune escape.
- Trial name
- HLH (NCT04944511)
- Testing
- Toripalimab Injection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Hepatitis B, Liver Cirrhosis
Effect of Entecavir Treatment on Regression and Disease Outcome in HBV-induced Liver Fibrosis and Cirrhosis Patients
Patients who have completed 2 years follow-up of the past National 12th Five-Year Major Project on Infectious Diseases will receive another 8 years treatment with entecavir (10 years in total).
- Trial name
- NCT02849132
- Testing
- Entecavir
- Where
- 20 sites in China
- Volunteers
- 800 people
- Sponsor
- Beijing Friendship Hospital
Chronic Hepatitis B
Improvement of Hard Endpoint in Chronic Hepatitis B Patients Treated With Antiviral Therapy
Patients who have completed 3 years follow-up of the past Beijing Science and Technology Commission Research will receive another 7-years anti-viral therapy.
- Trial name
- NCT03366571
- Testing
- Nucleos(t)ide Analogues
- Where
- 4 sites in China
- Volunteers
- 600 people
- Sponsor
- Beijing Friendship Hospital