Clinical trials: sponsored by Beijing Tiantan Hospital
Ischemic Stroke or High-risk TIA (ABCD² ≥ 4)
INtensive liPid-lowering Therapy for Acute High-risk IntracRanial or Extracranial atheroSclerosis -II (INSPIRES-2)
The research team is conducting a randomized, double-blind, placebo-controlled, multicenter clinical study aimed at evaluating the impact of adding Tolecilimab (a PCSK9 inhibitor) to standard lipid-lowering therapy (statins ±…
- Trial name
- NCT07341958
- Testing
- Tafolecimab
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Beijing Tiantan Hospital
Myofascial Trigger Points, Migraine
Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)
Chronic musculoskeletal pain (CMP) is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life. Knee osteoarthritis is a common type of CMP.
- Conditions
- Myofascial Trigger Points, Migraine, Cervicogenic Headache, Chronic Musculoskeletal Pain
- Trial name
- NCT07347028
- Testing
- MTrPs Injection, Intra-articular(IA) Injection
- Where
- China
- Volunteers
- 238 people
- Sponsor
- Beijing Tiantan Hospital
Mild Cognitive Impairment
Study on Ginkgo Biolba Extract Fifty and Mild Cognitive Impairment Associated With CSVD
This study aimed to explore the efficacy and safety of Ginkgo Biolba Extract fifty in treating mild cognitive impairment associated with cerebral small vessel disease (CSVD).
- Trial name
- GRACE (NCT06495476)
- Testing
- Ginkgo biloba extract 50 dropping pills, Ginkgo biloba extract Ginkgo biloba extract 50 Drops simulant
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Beijing Tiantan Hospital
Vagus Nerve Stimulation
Transauricular Vagus Nerve Stimulation Improves Postoperative Sleep Disorders in Elderly Patients.
Postoperative sleep disorder is one of the common complications after general anesthesia. Compared to patients of various ages, elderly patients have a much higher incidence of postoperative sleep disturbance.
- Trial name
- Vnstep (NCT06421051)
- Testing
- Transauricular Vagal Nerve Stimulation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Beijing Tiantan Hospital
Pituitary Neuroendocrine Tumors
A Comparative Study of Patients Undergoing Surgery for Pituitary Neuroendocrine Tumors Detected by Different Ways
This multicenter cohort study is based on the National Brain Tumor Registry of China (NBTRC). It will compare patients who underwent surgery for Pituitary Neuroendocrine Tumors (PitNETs) detected through health screening versus…
- Trial name
- NCT07835412
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Beijing Tiantan Hospital
Cerebral Amyloid Angiopathy
Jiedu Huayu Oral Prescription in the Treatment of Intracranial Hemorrhage Associated With Cerebral Amyloid Angiopathy
Cerebral hemorrhage, as a serious cerebrovascular disease, has the highest disability rate and mortality rate among all types of cerebrovascular diseases .It has brought a heavy burden to society.
- Trial name
- CHN-CAA (NCT07250035)
- Testing
- Jiedu Huayu Oral Prescription
- Where
- China
- Volunteers
- 436 people
- Sponsor
- Beijing Tiantan Hospital
WHO Grade III Gliomas, WHO Grade IV Gliomas
Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas
This is a single-center, open-label, multi-dose phase I clinical trial evaluating the safety, tolerability, and preliminary efficacy of ZSNeo-DC1.1, a personalized dendritic cell injection, in subjects with recurrent or…
- Trial name
- NCT06253234
- Testing
- personalized dendritic cell injection ZSNeo-DC1.1
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Beijing Tiantan Hospital
Symptomatic Intracranial Atherosclerotic Stenosis
Drug-Coated Balloon vs Aggressive Medical Management for High-Risk Symptomatic Intracranial Atherosclerotic Stenosis
DR.BEYOND-2 is an investigator-initiated, prospective, multicenter, randomized, open-label, blinded-endpoint, parallel-group clinical trial designed to evaluate the efficacy and safety of drug-coated balloon (DCB) angioplasty…
- Trial name
- DRBEYOND2 (NCT07830277)
- Testing
- Drug-Coated Balloon Angioplasty, Aggressive Medical Management
- Where
- 2 sites in China
- Volunteers
- 570 people
- Sponsor
- Beijing Tiantan Hospital
Fibromyalgia (FM)
Electroconvulsive Therapy for Refractory Fibromyalgia
This multicenter, prospective, randomized, open-label, wait-list controlled trial will evaluate the efficacy and safety of bilateral electroconvulsive therapy (ECT) for adults with refractory fibromyalgia (FM).
- Trial name
- NCT07835516
- Testing
- Electroconvulsive Therapy, Standard medical treatment
- Volunteers
- 58 people
- Sponsor
- Beijing Tiantan Hospital
Post-traumatic Olfactory Dysfunction, Traumatic Brain Injury
Acupuncture for Post-traumatic Olfactory Dysfunction: A Randomized Controlled Trial
The goal of this clinical trial is to learn if acupuncture based on the "Form-Qi-Spirit" theory works to treat post-traumatic olfactory dysfunction in adults. It will also learn about the safety of this acupuncture treatment.
- Conditions
- Post-traumatic Olfactory Dysfunction, Traumatic Brain Injury, Olfactory Dysfunction
- Trial name
- NCT07834047
- Testing
- Acupuncture, Corticosteroid therapy
- Where
- 2 sites in China
- Volunteers
- 84 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke
Efficacy and Safety of Human Urinary Kallidinogenase for Acute Ischemic Stroke Patients Receiving Reperfusion Treatment
This study aims to explore the efficacy and safety of Human Urinary Kallidinogenase for acute ischemic stroke patients receiving intravenous thrombolysis and/or endovascular treatment.
- Trial name
- UNITE (NCT06848894)
- Testing
- Human urinary kallidinogenase (HUK)
- Where
- China
- Volunteers
- 1,204 people
- Sponsor
- Beijing Tiantan Hospital
Guillain-Barré Syndrome
Efficacy and Safety of Efgartigimod in the Treatment of Guillain-Barré Syndrome(GREAT)
The goal of this clinical trial is to evaluate the safety and effectiveness of Efgartigimod in patients with Guillain-Barre syndrome (GBS).
- Trial name
- GREAT (NCT07806916)
- Testing
- Intravenous immunoglobulin (IVIG), Efgartigimod Alfa-Fcab
- Volunteers
- 110 people
- Sponsor
- Beijing Tiantan Hospital
Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection
Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone for Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection, Segmentectomy, Lobectomy of the Lungs
- Trial name
- NCT07603921
- Testing
- Pre-incisional infiltration with ropivacaine plus triamcinolone, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 346 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Aneurysm
A Multicenter Prospective Study of New Flow Diverter Stent on the Treatment of Intracranial Aneurysms in China
Intracranial aneurysm, as a common cerebrovascular disease, has a variety of treatment methods, including surgical treatment and endovascular treatment.
- Trial name
- APRESENT (NCT07821957)
- Testing
- Novel Flow Diverter Stent
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
Safety and Preliminary Efficacy of NXL-001 in Patients With Ischemic Stroke
This is a single-arm, open-label, single center, dose-escalation exploratory clinical study to evaluate the safety and tolerability of a single intracerebral injection of NXL-001, a NeuroD1 base gene therapy, in patients with…
- Trial name
- NXL-001 (NCT06761183)
- Testing
- intracerebral stereotactic injection of NXL-001
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Tumors
The Effect of Ciprofol Versus Propofol Anesthesia on Postoperative Neurological Complications
Postoperative delirium and postoperative ischemic stroke are common neurological complications in clinical practice. The incidence of these complications is further increased in patients undergoing neurosurgical procedures.
- Trial name
- NCT07805876
- Testing
- Ciprofo, Propofol
- Where
- China
- Volunteers
- 434 people
- Sponsor
- Beijing Tiantan Hospital
Bladder Pain Syndrome, Educational Behavioral Intervention
Mirogabalin Plus EBMP for IC/BPS
The goal of this clinical trial is to learn whether adding mirogabalin to educational-behavioral modification program (EBMP) improves symptoms and safety outcomes for adults living with interstitial cystitis/bladder pain syndrome…
- Conditions
- Bladder Pain Syndrome, Educational Behavioral Intervention, Urinary Urgency
- Trial name
- M-EBMP-IC/BPS (NCT07803393)
- Testing
- Behavioral: Educational and Behavioral Management Program (EBMP), Intervention
- Volunteers
- 200 people
- Sponsor
- Beijing Tiantan Hospital
Anxiety, Dexmedetomidine
The Impact of Dexmedetomidine Nasal Spray on Perioperative Anxiety in Neurosurgical Patients
This randomized clinical trial aims to evaluate the effect of preoperative use of dexmedetomidine nasal spray on improving perioperative anxiety levels in patients undergoing elective supratentorial tumor resection.
- Trial name
- NCT07801014
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Beijing Tiantan Hospital
Herpes Zoster, Pain
The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster
Postherpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ) and represents a major clinical challenge due to its chronicity and impact on quality of life.
- Conditions
- Herpes Zoster, Pain, Postherpetic Neuralgia
- Trial name
- NCT07361796
- Testing
- Venlafaxine combined conventional therapy, Conventional therapy
- Where
- China
- Volunteers
- 832 people
- Sponsor
- Beijing Tiantan Hospital
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin Combined With Venlafaxine in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Venlafaxine, Pain
- Trial name
- NCT07186751
- Testing
- Pregabalin, Pregabalin with venlafaxine
- Where
- 2 sites in China
- Volunteers
- 750 people
- Sponsor
- Beijing Tiantan Hospital