Clinical trials: sponsored by Beijing Tiantan Hospital
Acute Ischemic Stroke
The Trial of Ewata Balloon Guiding in the Application of Thrombectomy
To evaluate the efficacy and security of Ewata combined with a stent device in the treatment of acute ischemic stroke within 8 hours To prove whether the clinical efficacy and safety of Ewata r is not inferior to other guidings.
- Trial name
- NCT04315844
- Testing
- Ewata balloon guiding
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Postoperative
Pre-emptive Scalp Infiltration With Methylprednisolone Plus Ropivacaine for Postoperative Pain After Craniotomy
Pain is common for the first 2 days after major craniotomy. A majority of patients would suffer from moderate-to-severe postoperative pain after undergoing craniotomy.
- Trial name
- NCT04078139
- Testing
- The MP/RP group, The RP group
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Pain, Lidocaine
Pre-emptive Topical Lidocaine 5% Plaster for Prevention of Post-craniotomy Pain
Postcraniotomy pain remains a common phenomenon in the neurosurgery field. Managements for postcraniotomy pain are to be standardised and optimized.
- Trial name
- EASY (NCT04169854)
- Testing
- Lidocaine 5% patch
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Tiantan Hospital
Epilepsy
Clinical Trial of MgLiTT for Medical Refractory Epilepsy
Multicenter, open-label, prospective designed study to characterize the performance of MRI-guided laser interstitial thermal therapy (MgLiTT) using the Sinovation Laser Ablation System for the treatment of medical refractory…
- Trial name
- NCT04569071
- Testing
- Sinovation Laser Ablation System
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tiantan Hospital
Anesthesia, Outcome, High-grade Glioma
The Impact of Anesthesia on High- Grade Glioma Patients
Although bench data and retrospective studies have provided a promising picture of the possible influence of anesthetic technique on the risk of tumor progression and patients mortality, current evidence from RCTs is inadequate…
- Trial name
- NCT02756312
- Testing
- IV Anesthesia, IH anesthesia
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Supratentorial Brain Tumor
Effects of Pre-emptive Scalp Infiltration With Low-dose Ketorolac and Ropivacaine for Postoperative Pain
The PAINLESS study is a single-center, prospective, randomized, open-label, blinded-endpoint (PROBE) controlled clinical pilot study to compare the efficacy and safety of pre-emptive scalp infiltration with ropivacaine plus…
- Trial name
- PAINLESS (NCT04380298)
- Testing
- Ketorolac, Ropivacaine, Epinephrine
- Volunteers
- 40 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Hemorrhage, Aneurysmal, Cerebral Vasospasm
Stellate Ganglion Block in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage
To investigate whether the stellate ganglion block is helpful in relieving cerebral vasospasm during aneurysmal coil embolism surgery. The effect was assessed by Transcranial Doppler (TCD).
- Trial name
- NCT04512859
- Testing
- Stellate Ganglion Block
- Volunteers
- 160 people
- Sponsor
- Beijing Tiantan Hospital
Stroke
An AI-Based CDSS for Integrated Management of Patients With Acute Ischemic Stroke(GOLDEN BRIDGE II)
This study will conduct a cluster randomized controlled trial to evaluate the impact of an artificial intelligence-based clinical decision support system for the integrated management of patients with acute ischemic stroke on the…
- Trial name
- NCT04524624
- Testing
- AI-based CDSS
- Where
- China
- Volunteers
- 21,689 people
- Sponsor
- Beijing Tiantan Hospital
Colorectal Neoplasms, Aged
Effect of Transversus Abdominis Plane Block Combined With Dexmedetomidine Infusion on the Prognosis in Elderly Patients Undergoing Abdominal Surgery
To compare the prognosis of elderly patients undergoing radical resection of colorectal cancer treated with general anesthesia and general anesthesia combined with transversus abdominis plane block and continuous infusion of…
- Trial name
- NCT04516174
- Testing
- Transversus abdominis plane block using ropivacaine, Dexmedetomidine, Transversus abdominis plane block using saline
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Tiantan Hospital
Carotid Artery Occlusion
Multi-dimensional Evaluation System for Recanalization of Symptomatic Non-acute Carotid Artery Occlusion
This is a multi-center, prospective, exploratory, observational, registration study on patients with symptomatic non-acute carotid artery occlusion to initially evaluate the safety and efficacy of endovascular treatment.
- Trial name
- NCT04291430
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Arterial Stenosis
Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging
1. It is a multicenter, open-label, sing arm study to evaluate the effects of treatment of Rosuvastatin 10-20mg in volume and morphology of atherosclerotic plague by reducing LDL-C level to or less than 70mg/dl. 2.
- Trial name
- REALM (NCT02041117)
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Ischemic Attack, Transient
Platelet Reactivity in Acute Non-disabling Cerebrovascular Events
Ticagrelor is a reversible and direct-acting oral antagonist of the P2Y12 (Purinergic receptor P2Y, G-protein coupled, 12) receptor for adenosine diphosphate, which provides faster, greater, and more consistent P2Y12 inhibition…
- Trial name
- PRINCE (NCT02506140)
- Testing
- Ticagrelor and Acetylsalicylic acid, Clopidogrel and Acetylsalicylic acid
- Where
- 25 sites in China
- Volunteers
- 675 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute, Transient Ischemic Attack
Genetic Identification of Monogenic Disorders in Early-onset Stroke Using Targeted Next Generation Sequencing Panel
The study was designed as a multicenter multiracial prospective observational study of acute ischemic stroke and TIA patients across china.
- Conditions
- Stroke, Acute, Transient Ischemic Attack, Single-gene Disorders
- Trial name
- MDEOS (NCT04485598)
- Where
- China
- Volunteers
- 502 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Cerebral Infarction
Efficacy and Safety Study of Neu2000KWL for Acute Ischemic Stroke Patients Within 6 Hours of Onset
The purpose of the study is to explore safety and efficacy of Salfaprodil administration for patients with acute ischemic stroke within 6 hours of onset.
- Trial name
- Salfaprodil (NCT04486430)
- Testing
- Neu2000KWL
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Beijing Tiantan Hospital
Embolic Stroke
Shuxuetong for Prevention of Recurrence in Acute Cerebrovascular Events With Embolism
This is a randomized, double blind, placebo-controlled, parallel, multicenter research in order to evaluate the effect of Shuxuetong injection in prevention of symptomatic or asymptomatic new cerebral infarction within 10 days.
- Trial name
- SPACE (NCT03090113)
- Testing
- Shuxuetong Injection
- Where
- 48 sites in China
- Volunteers
- 2,416 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Postoperative, Children
Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-Craniotomy Pain in Children
At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the…
- Trial name
- NCT04051723
- Testing
- The dexamethasone plus ropivacaine, The ropivacaine
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Transient Ischemic Attack
Clopidogrel in High-risk Patients With Acute Non-disabling Cerebrovascular Events
The purpose of this study is to assess the effects of a 3-month regimen of clopidogrel initiated with a loading dose (LD) of 300 mg followed by 75 mg/day during the first 21days versus a 3-month regimen of ASA 75 mg/day alone on…
- Trial name
- CHANCE (NCT00979589)
- Testing
- Clopidogrel
- Where
- China
- Volunteers
- 5,100 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
Intervention to Bridge the Evidence-based Gap in Stroke Care Quality
The purpose of this study is to evaluate whether a multifaceted quality improvement intervention can improve the adherent rate of individual and composite of evidence-based performance measures for patients with acute ischemic…
- Trial name
- GoldenBridge (NCT02212912)
- Testing
- improvement intervention, no intervention
- Where
- China
- Volunteers
- 4,800 people
- Sponsor
- Beijing Tiantan Hospital
Vascular Cognitive Impairment, Dementia, Vascular
Efficacy and Safety of Ferrous Iron on the Prevention of Vascular Cognitive Impairment Among Patients With Cerebral Infarction/TIA (FAVORITE)
The prevalence of Vascular Cognitive Impairment(VCI) is high in patients after ischemic stroke or transient ischemic attack(TIA) . Effective therapy for the prevention of VCI remains limited.
- Conditions
- Vascular Cognitive Impairment, Dementia, Vascular, Iron-deficiency, Cerebral Infarction
- Trial name
- FAVORITE (NCT03891277)
- Testing
- Ferrous succinate
- Where
- China
- Volunteers
- 1,006 people
- Sponsor
- Beijing Tiantan Hospital
Ketamine; Depressive Symptom; Neurosurgery; Perioperative Period
Ketamine and Postoperative Depressive Symptom-PASSION
Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay.
- Trial name
- NCT03086148
- Testing
- Ketamine, Normal saline
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Beijing Tiantan Hospital