Clinical trials: sponsored by Beijing Tiantan Hospital
Delirium, Brain Tumor
A Study for Postoperative Delirium in Older Patients With Intracranial Tumors
Postoperative delirium is a common acute central nervous system syndrome, which often occurs 1-5 days after surgery. Postoperative delirium can prolong the length of hospital stay, increase the mortality rate, and is also…
- Trial name
- NCT07797660
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Beijing Tiantan Hospital
PARKINSON DISEASE (Disorder), Deep Brain Stimulation
Anesthesia and Postoperative Delirium in Parkinson DBS
Parkinson's disease (PD) is the second most common neurodegenerative disorder, with a rising incidence due to global aging. Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is a core therapeutic modality for motor…
- Conditions
- PARKINSON DISEASE (Disorder), Deep Brain Stimulation, Postoperative Delirium
- Trial name
- POD-DBS-PD (NCT07792265)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Beijing Tiantan Hospital
Dexmedetomidine, Postoperative Delirium
Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium in Elderly Patients
Postoperative delirium (POD) is a common surgical complication. The incidence is 10% to 22% in neurological procedures, and advanced age is a risk factor for neurological procedures.
- Trial name
- NCT05168280
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- 2 sites in China
- Volunteers
- 420 people
- Sponsor
- Beijing Tiantan Hospital
Irritable Bowel Syndrome
Efficacy of Esketamine for Patients With Irritable Bowel Syndrome
To explore the efficacy of a single low dose of esketamine for patients with irritable bowel syndrome (IBS).
- Trial name
- NCT06788444
- Testing
- The colonoscopy, Esketamine
- Where
- China
- Volunteers
- 552 people
- Sponsor
- Beijing Tiantan Hospital
Insomnia, Digestive Endoscopy
Changes in Intravenous Anesthetic Drug Dosage in Insomnia Patients Undergoing Digestive Endoscopy
To compare the dosage requirement of intravenous anesthetics during digestive endoscopy between patients with insomnia and those with normal sleep pattern.
- Trial name
- NCT06376760
- Testing
- No interventions, it is a observational study
- Where
- China
- Volunteers
- 3,360 people
- Sponsor
- Beijing Tiantan Hospital
Herpes Zoster Pain
Efficacy and Safety of Intravenous Dexamethasone Palmitate Treatments in Acute and Subacute Herpes Zoster Pain
This is a randomized, prospective, multicenter, open-label, blinded-endpoint study investigating the efficacy and safety of dexamethasone palmitate (DXP) for treating acute and subacute herpes zoster (shingles) pain.
- Trial name
- NCT07344246
- Testing
- intravenous infusion with 4 mg dexamethasone palmitate or 8 mg dexamethasone palmitate
- Where
- China
- Volunteers
- 954 people
- Sponsor
- Beijing Tiantan Hospital
Cerebral Venous Sinus Thrombosis
Endovascular Treatment or Standard Medical Care for Cerebral Venous Sinus Thrombosis(ESCORT)
Background: It has not been extensively studied in differing populations that endovascular treatment (EVT) for acute and subacute CVST with multimodal imaging selection improves the functional outcome better than standard medical…
- Trial name
- ESCORT (NCT06583889)
- Testing
- Heparin, Endovascular treatment
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Aneurysm, Aneurysm, Brain
Dimethyl Fumarate Treatment for Intracranial Unruptured Aneurysms.
This study was designed to identify whether there is a measurable reduction in inflammation in walls of intracranial aneurysms with oral dimethyl fumarate.
- Conditions
- Intracranial Aneurysm, Aneurysm, Brain, Inflammation Vascular
- Trial name
- NCT05959759
- Testing
- Dimethyl fumarate
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Postoperative, Dexamethasone Palmitate
Dexamethasone Palmitate for Postoperative Pain
Postoperative pain remains highly prevalent and inadequately managed in a significant proportion of surgical patients, often leading to delayed recovery, increased opioid consumption, and potential progression to chronic pain.
- Trial name
- NCT07341854
- Testing
- dexamethasone palmitate, Dexamethasone
- Where
- China
- Volunteers
- 446 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
A Phase 3 Trial of Lesion Network Mapping-Guided cTBS for Motor Recovery After Acute Ischemic Stroke
This Phase 3 study will evaluate whether lesion network mapping-guided continuous theta burst stimulation (cTBS) can improve recovery after acute ischemic stroke.
- Trial name
- MASTRE-3 (NCT07645586)
- Testing
- LNM-navigated cTBS
- Where
- China
- Volunteers
- 584 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
A Phase 2b Trial of Lesion Network Mapping-Guided cTBS for Motor Recovery After Acute Ischemic Stroke
This Phase 2b study will evaluate whether lesion network mapping-guided continuous theta burst stimulation (cTBS) can improve recovery after acute ischemic stroke.
- Trial name
- MASTRE-2 (NCT07645560)
- Testing
- LNM-navigated cTBS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Focal Epilepsy, Intraoperative Monitoring
High-density Flexible μECoG for Epilepsy Surgery - A Single-Arm ECT
What's the clinical value of high-density flexible microelectrocorticography (μECoG) for guiding the resection of epileptogenic zone (EZ) in epilepsy surgery?
- Trial name
- Epi-PRECISE (NCT07656857)
- Testing
- Using High-density Flexible microElectrocorticography for intraoperative monitoring
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Beijing Tiantan Hospital
Moyamoya Disease, Moyamoya Syndrome
Evaluating Antiplatelet and Physical Therapy for Slowing Progression in Mild Moyamoya Disease.
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease characterized by progressive stenosis or occlusion at the terminal portion of the internal carotid artery, with formation of an abnormal vascular network at…
- Conditions
- Moyamoya Disease, Moyamoya Syndrome, Aspirin, Remote Ischemic Conditioning
- Trial name
- MOUNT-EASE (NCT07762547)
- Testing
- aspirin treatment, Remote Ischemic Conditioning
- Where
- China
- Volunteers
- 724 people
- Sponsor
- Beijing Tiantan Hospital
Disorders of Consciousness, Spontaneous Intracerebral Hemorrhage
Transcutaneous Auricular Vagus Nerve Stimulation for Recovery of Consciousness After Surgery for Spontaneous Intracerebral Hemorrhage
Disorders of consciousness are common after surgery for severe spontaneous intracerebral hemorrhage and are associated with high mortality, disability, and long-term dependence.
- Trial name
- TAVNS-SICH (NCT07761507)
- Testing
- Active Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Beijing Tiantan Hospital
Alzheimer Disease
Multisensory 40-Hz Stimulation for Alzheimer's Disease
This study aims to evaluate the safety and preliminary efficacy of combined auditory and visual 40-Hz stimulation in participants with biomarker-confirmed Alzheimer's disease spectrum disorders.
- Trial name
- NCT07758751
- Testing
- Multisensory 40-Hz Stimulation Device
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Bladder Pain Syndrome, Pregabalin
Efficacy and Safety of Pregabalin Combined With Educational and Behavioral Intervention for Bladder Pain Syndrome/Interstitial Cystitis
Bladder pain syndrome/interstitial cystitis (IC/BPS) brings long-term pelvic pain, frequent urination and poor sleep quality, which severely lowers patients' daily life quality.
- Conditions
- Bladder Pain Syndrome, Pregabalin, Educational Behavioral Intervention, Urinary Urgency
- Trial name
- PEBI-ICBPS (NCT07752134)
- Testing
- Educational and Behavioral Management Program (EBMP), Pregabalin
- Volunteers
- 200 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Intractable
A Study of the Safety and Tolerability of GA in the Treatment of Patients With Refractory Neuropathic Pain
Previous studies have shown that the anterior cingulate cortex is involved in the regulation of pain and its associated negative emotions, that pyramidal neurons are highly excitable in chronic neuropathic pain conditions, and…
- Trial name
- NCT06596681
- Testing
- GA+clozapine
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Beijing Tiantan Hospital
Non-specific Low Back Pain, Pain Management
Venlafaxine for Non-specific Low Back Pain
Chronic non-specific low back pain is the leading cause of productivity loss and disability worldwide, constituting a major public health challenge.
- Trial name
- NCT07737158
- Testing
- Control Group, Venlafaxine group
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Beijing Tiantan Hospital
Non-specific Low Back Pain
Toludesvenlafaxine for Non-specific Low Back Pain
Chronic non-specific low back pain is the leading cause of productivity loss and disability worldwide, constituting a major public health challenge.
- Trial name
- NCT07709416
- Testing
- Active Comparator #1, Toludesvenlafaxine
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Beijing Tiantan Hospital
Insomnia, Digestive Endoscopy
Changes in Rimazolen Dosage in Patients With Insomnia Under Intravenous Anesthesia
To compare the dosage requirement of rimazolen under intravenous anesthesia between patients with insomnia and those with normal sleep pattern.
- Trial name
- NCT07028190
- Testing
- No interventions, it is a observational study
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Beijing Tiantan Hospital