Clinical trials: sponsored by Beijing Tongren Hospital
Extranodal NK/T-cell Lymphoma
Selinexor Combined With Reduced-Dose Radiotherapy For Early-Stage Extranodal NK/T-Cell Lymphoma
Extranodal NK/T-cell lymphoma (ENKTCL) is an Epstein-Barr virus-associated non-Hodgkin lymphoma with high incidence in Asia and Latin America.
- Trial name
- NCT07554482
- Testing
- Pegaspargase (PEG) Asparaginase, Gemcitabine (GEM), Oxaliplatin
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Primary Central Nervous System Lymphoma (PCNSL), Diffuse Large B Cell Lymphoma (DLBCL)
Pomalidomide, Anti-PD-1 Antibody Combined With Selinexor (PPS) in Relapsed/Refractory Primary Central Nervous System Diffuse Large B-Cell Lymphoma
Primary central nervous system diffuse large B-cell lymphoma (PCNSL-DLBCL) is a highly aggressive malignancy accounting for over 80% of primary CNS lymphomas, with an annual incidence of 0.4-0.6 per 100,000 people globally and a…
- Trial name
- NCT07523737
- Testing
- Pomalidomide, PD-1 / PD-L1 monoclonal antibody, XPO1 inhibitor
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Beijing Tongren Hospital
Neuromuscular Blocking Agents
Antagonism of Neostigmine in Continuous Infusion of Mivacurium
In this study, the antagonism of neostigmine, a cholinesterase inhibitor, on continuous infusion of mivacurium during foot and ankle surgery under general anesthesia was investigated, and the appropriate time point of antagonism…
- Trial name
- NCT07524959
- Testing
- Neostigmine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Extranodal NK T Cell Lymphoma, Hemophagocytic Lymphohistiocytosis (HLH)
Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)
Extranodal NK/T-cell lymphoma (NKTCL) is an aggressive EBV-associated lymphoma with poor prognosis, highly prevalent in China. Early-stage NKTCL achieves favorable long-term survival, while advanced disease shows dismal outcomes…
- Trial name
- NCT07525466
- Testing
- Mitoxantrone liposome, Etoposide, Pegaspargase (PEG) Asparaginase
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Beijing Tongren Hospital
Emergence Agitation
Auricular Acupressure for Reducing Postoperative Emergence Agitation in Preschool Children
This study investigates whether auricular acupressure can reduce postoperative emergence agitation among preschool children following adenoidectomy.
- Trial name
- NCT07472764
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tongren Hospital
Myopia
Evaluation of the Efficacy of Red Light in Adult Patients With High and Extreme Myopia
This study, led by Jie ying from the Ophthalmology Department of Beijing Tongren Hospital Affiliated to Capital Medical University, is a researcher-initiated clinical trial (IIT) designed to evaluate the therapeutic efficacy of…
- Trial name
- NCT07412678
- Testing
- Red light, Single vision spectacle lenses
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Beijing Tongren Hospital
High Myopia, Low Concentration Atropine
Low Concentration Atropine Combined With Soft Contact Lens in Controlling Myopia Progression in Children With High Myopia
Peripheral contact lens in controlling myopia progression in high myopia children（PAM）is a prospective, single-center, randomized controlled trial with three parallel arms conducted at Beijing Tongren Hospital.
- Conditions
- High Myopia, Low Concentration Atropine, Soft Contact Lens, Children
- Trial name
- NCT07406399
- Testing
- soft peripheral defocus contact lenses, Atropine 0.04%, Atropine (0.01%)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Myopia
Development of Bioluminescent Myopia Prevention and Control Instrument and Evaluation of Its Effect on Myopia
Based on the Tongren Myopia and Amblyopia Therapeutic Apparatus (a 650nm low-level red-light device) developed by the research team in the previous phase, the device was modified by replacing the light source with LED light.
- Trial name
- NCT07208617
- Testing
- RED-light device using LED light source, Control
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Beijing Tongren Hospital
Diffuse Large B Cell Lymphoma (DLBCL)
Application of Zanubrutinib-based Combination Regimens in the Treatment of Newly-diagnosed Diffuse Large B-cell Lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. Currently, the first-line treatment regimen based on R-CHOP can only achieve clinical cure for 50% to 60% of patients.
- Trial name
- NCT07371923
- Testing
- Zanubrutinib+Pola-R-CHP
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Tongren Hospital
Marginal Zone Lymphoma(MZL)
Application of Orelabrutinib With or Without CD20 Monoclonal Antibody in Previously Untreated Marginal Zone Lymphoma
This study focuses on treatment-naïve marginal zone lymphoma (MZL) patients and aims to investigate the efficacy and safety of orelabrutinib combined with or without CD20 monoclonal antibody.
- Trial name
- NCT07355699
- Testing
- Orelabrutinib
- Where
- 3 sites in China
- Volunteers
- 88 people
- Sponsor
- Beijing Tongren Hospital
Children With Myopia, Treatment
Clinical Study on the Effectiveness of Diverse Segments Defocus Optimization in Spectacle Lenses for Slowing Myopia Progression
Clinical Trial The goal of this clinical trial is to evaluate the effectiveness of two types of Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses in slowing myopia progression in children.
- Conditions
- Children With Myopia, Treatment, Multizone Lens Design for Myopic Defocus, Visual Quality
- Trial name
- NCT07323251
- Testing
- Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Visual Fatigue
Evaluating the Effectiveness of Comfort Reading Mode in Preventing Dry Eyes and Visual Fatigue
The purpose of this study was to investigate the effects of visual fatigue and dry eye level under different reading background polarities and different text colours, and to evaluate the effect of comfortable reading mode on the…
- Trial name
- NCT07032909
- Testing
- comfortable reading mode
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Blue-blocking Glasses
Visual Health Evaluation of New Designed Blue-blocking Glasses
With the widespread use of electronic display devices, the potential hazards of blue light have become an important public health issue.
- Trial name
- NCT06984783
- Testing
- The new type of filtering glasses can efficiently filter out the high-energy blue and green light within a narrow wavelength band.
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Visual Fatigue, Myopia
Exploring the Impact of Dynamic Defocus Display Schemes on Ocular Health Indicators
The present study is designed to explore the effects of dynamic defocus display technology on ocular health parameters using rigorous scientific approaches.
- Trial name
- NCT07291856
- Testing
- Dynamic Defocus Mode
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Seasonal Allergic Rhinitis
Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis
Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E after exposure to allergens in atopic individuals.
- Trial name
- MEGREZ (NCT06300203)
- Testing
- Interleukin-4 receptor responders
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Hypertension, Diabetes Mellitus
Retinal Vascular Manifestations in Patients With Common Internal Diseases on OCTA Tomography Angiography
Hypertension, diabetes mellitus, and dyslipidemia are common internal diseases, and all diseases are atherosclerosis risk factors.
- Conditions
- Hypertension, Diabetes Mellitus, Dyslipidemias
- Trial name
- NCT05644548
- Testing
- No intervention
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tongren Hospital
Dry Eye, TCM
Ganyan-1 in Dry Eye
Ganyan -1 for the patients with dry eye
- Trial name
- NCT06818487
- Testing
- Ganyan1, Sodium Hyaluronate, 1/2Ganyan1
- Volunteers
- 219 people
- Sponsor
- Beijing Tongren Hospital
Head and Neck Cancers
A Prospective, Multicenter, Multicohort Phase II Study: Evaluating the Efficacy and Safety of Preoperative Neoadjuvant Treatment With a PD-1 Inhibitor in Combination With Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) refers to a series of tumors that occur in the head and neck region, including the oral cavity, pharynx, larynx, nasal cavity, paranasal sinuses, thyroid gland, and salivary glands.
- Trial name
- NCT06894459
- Testing
- Pembrolizumab, Cisplatin, Nab-paclitaxel
- Volunteers
- 180 people
- Sponsor
- Beijing Tongren Hospital
Obstructive Sleep Apnea Syndrome
Apneic Oxygenation by Transnasal Humidified Rapid Insufflation Ventilator Exchange Obstructive Sleep Apnea Patients
The purpose of the study is to compare effectiveness of different methods of achieving oxygenation in obstructive sleep apnea patients.
- Trial name
- THRIVE (NCT06581588)
- Testing
- THRIVE, THRIVE combine nasopharyngeal airway
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Beijing Tongren Hospital
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital