Clinical trials: sponsored by Boston Medical Center
HIV Infection, Alcohol Use
Zinc for HIV Disease Among Alcohol Users - an RCT in the Russia ARCH Cohort
This study is a double-blinded randomized controlled trial (RCT) to assess the efficacy of zinc supplementation vs. placebo among 250 HIV-infected Russians from the Russia ARCH Cohort, who are ART-naive at enrollment and have a…
- Trial name
- ZINC (NCT01934803)
- Testing
- Zinc gluconate
- Where
- Russia
- Volunteers
- 254 people
- Sponsor
- Boston Medical Center
Traumatic Brain Injury, Cognitive Dysfunction
Combined Transcranial Magnetic Stimulation and Cognitive Treatment in Blast Traumatic Brain Injury
This study investigates the efficacy of a novel neurorehabilitation program combining noninvasive brain stimulation (transcranial magnetic stimulation or TMS) and cognitive therapy, on cognitive function and quality of life in…
- Conditions
- Traumatic Brain Injury, Cognitive Dysfunction, Blast Injury
- Trial name
- COST-TBI (NCT01596569)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Intervention
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Boston Medical Center
Heart Failure
CRUSH STUDY: Calculating Readmission Risk by Ultrasound for Heart Failure Failure Study
This is a study to determine if two ultrasound measures (Corrected Flow Time and B-Lines) can predict patients at higher risk of readmission within 30 days of hospital discharge for decompensated heart failure.
- Trial name
- CRUSH (NCT02996032)
- Testing
- Vascular and Pulmonary Ultrasound
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Boston Medical Center
Otorrhea, Otitis Media With Effusion in Children
Otiprio Versus Ciprodex Tympanostomy Tube Outcomes
Otolaryngologists routinely administer ear drops at the time of tympanostomy tube placement in order to prevent tube otorrhea; however, there is a lack of consensus as to which drops are the most effective, and whether a…
- Trial name
- NCT03347461
- Testing
- Otiprio, Ciprodex
- Where
- United States
- Sponsor
- Boston Medical Center
AL Amyloidosis
Trial of High Dose Melphalan/Stem Cell Transplant With or Without Bortezomib
Standard treatment for AL Amyloidosis is high-dose melphalan and stem cell transplant. This study will compare the safety and effectiveness of standard treatment with high-dose melphalan and stem cell transplant, compared with…
- Trial name
- VelRand (NCT02489500)
- Testing
- Bortezomib, Melphalan, Neupogen
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston Medical Center
Depression, Child Development
Improving Preterm Outcomes by Safeguarding Maternal Mental Health
The investigators' goal is to optimize the developmental outcomes of preterm infants by preventing depression and improving functioning among their mothers during the critical first year of life.
- Trial name
- NCT01892982
- Testing
- Problem Solving Education tailored to NICU
- Where
- 4 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Pouchitis, Irritable Pouch Syndrome
Nutritional Impact of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With IPAA
This is an open label trial to test the hypothesize that serum bovine immunoglobulin protein isolate (SBI) will improve the nutritional status and quality of life (QOL) of patients with an ileal pouch anal anastomosis (IPAA) and…
- Trial name
- NCT02828410
- Testing
- SBI
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Boston Medical Center
Child Maltreatment, Children With Special Health Care Needs (CSHCN)
A Pilot Intervention With Families of Children With Special Health Care Needs
This is a pilot randomized controlled trial of a behavioral intervention focused on improving parenting skills and preventing child neglect in families of children with special health care needs.
- Trial name
- NCT02742831
- Testing
- Intervention, Control
- Where
- United States
- Sponsor
- Boston Medical Center
Back Pain Lower Back Chronic
Yoga Dosing Study for Chronic Low Back Pain
A 12-week randomized controlled trial (RCT) for chronic low back pain in predominantly minority populations comparing yoga classes once/week vs. twice/week.
- Trial name
- YLBP2 (NCT01761617)
- Testing
- Yoga class once per week, Yoga class twice per week
- Where
- 6 sites in United States
- Volunteers
- 96 people
- Sponsor
- Boston Medical Center
Influenza-Like Illness, Influenza
Impact of Rapid Flu Testing in BMC ED
The purpose of the study is to compare Emergency Department patients who undergo influenza testing using an FDA-approved point-of-care device (Cobas Liat Influenza A/B assay) located in the ED, to patients whose samples are sent…
- Trial name
- FluProcess (NCT02979730)
- Testing
- Core Lab Test, ED Point of Care Test
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Boston Medical Center
Sexually Transmitted Infection
Long-Acting Progestin Contraception and the Vaginal Microbiome
Despite many years of research, controversy persists as to whether hormonal contraception promotes HIV acquisition. A number of observational studies on depot medroxyprogesterone acetate (DMPA) injection showed an increase in HIV…
- Trial name
- vMICROb (NCT02740998)
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Literacy, Information Disclosure
ECA vs E-Document Explanation
This study will investigate how consent forms and other health care documents are explained to patients. The findings will be used to create a computer program that can successfully explain consent and other health-related forms…
- Trial name
- NCT03381911
- Testing
- Embodied Conversational Agent
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
HPV-Related Carcinoma
Integrating Primary & Secondary Interventions for Cervical Cancer Prevention in Primary Care Settings
The purpose of this study is to determine whether a mobile health educational intervention for Human PapillomaVirus (HPV) Vaccination promotion and cervical cancer screening in Primary Care settings is a feasible behavioral…
- Trial name
- NCT03033550
- Testing
- brief negotiated mobile application
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Labor Pain
Best Beginnings for Babies Birth Sister Program Evaluation
Peer support during labor, birth and the perinatal period (also known as "doula" support) has been shown in some studies to reduce cesarean rates, postpartum depression and increase breastfeeding rates.
- Trial name
- BBB (NCT02550730)
- Testing
- Birth Sisters Best Beginnings for Babies, Usual maternity care
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- Boston Medical Center
Health Behavior
Behavioral CVD Prevention Using Informatics
Overweight/obesity is strongly linked to mortality from multiple chronic diseases, including cardiovascular disease, diabetes, and obesity-related cancers.The successful management of overweight/obesity requires management of…
- Trial name
- NCT02752464
- Testing
- Counseling, feedback report
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Boston Medical Center
Melasma
Treatment of Melasma With Glycolic Acid-Salicylic Acid Peel Versus Glycolic Acid Peel
The aim of this pilot study is to conduct a controlled comparison of the efficacy and safety of a combination peel (glycolic acid and salicylic acid) as compared to glycolic acid peel alone in the treatment of melasma.
- Trial name
- NCT02812719
- Testing
- Glycolic acid peel alone, Glycolic and salicylic acid peel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Patient Satisfaction, Patient Compliance
Study Buddy (an ECA Oncology Trial Advisor) for Cancer Trials
The Study Buddy ECA acts as an advisor to patients on chemotherapy regimens, promoting protocol adherence and retention, providing anticipatory guidance and answering questions, serving as a conduit to capture information about…
- Conditions
- Patient Satisfaction, Patient Compliance, Guideline Adherence
- Trial name
- NCT02742740
- Testing
- Chemo Buddy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Medical Center
HIV Infection, Drug Use
Linking Infectious and Narcology Care in Russia
The purpose of this study is to implement and assess a behavioral and structural intervention in Russia designed to support and motivate HIV-infected narcology heroin dependent patients (i.e., IDUs) to engage (i.e., initiate and…
- Trial name
- LINC (NCT01612455)
- Testing
- LINC Case Management
- Where
- 3 sites in Russia
- Volunteers
- 349 people
- Sponsor
- Boston Medical Center
Lung Cancer
Stereotactic Radiosurgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer
RATIONALE: Stereotactic radiosurgery can send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This phase I trial is studying the side effects and best dose of stereotactic radiosurgery in treating…
- Trial name
- NCT00852644
- Testing
- computed tomography, fludeoxyglucose F 18, hypofractionated radiation therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Medical Center
Diaper Rash, UTI
Diaper Distribution in Low-Income Infants
The adverse effects of poverty at the individual, family, and community level on health outcomes for children are well-established.
- Conditions
- Diaper Rash, UTI, Depressive Symptoms, Stress
- Trial name
- NCT03425851
- Testing
- Diapers, Resources of diaper banks
- Where
- United States
- Sponsor
- Boston Medical Center