Clinical trials: sponsored by Boston Medical Center
Cardiovascular Health, Obesity
Effects of the Atkins Diet Versus a Low Fat Diet on Inflammation
The purpose of this research is to assess the effects of a low-carbohydrate (modified Atkins) diet versus a low fat (Heart Healthy) diet on cardiovascular health.
- Trial name
- NCT00993278
- Testing
- Low-Carbohydrate (Modified Atkins) Diet, Low-Fat (Heart Healthy) Diet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Alcoholism, Alcohol Dependence
Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism
This is a double-blind, placebo-controlled, parallel group design study with 4 treatment groups; levetiracetam, zonisamide, topiramate, and placebo control. Subjects will receive study medications for 14 weeks.
- Conditions
- Alcoholism, Alcohol Dependence, Alcohol Abuse
- Trial name
- NCT00862563
- Testing
- Topiramate, Zonisamide, Levetiracetam
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Boston Medical Center
Diabetes Mellitus, Hypertension
Financial Incentives for Medication Adherence
This study is a pilot study. The investigators have designed a randomized, controlled trial of financial incentives in medication adherence, focusing primarily on poorly-controlled diabetes, and secondarily on hypertension, and…
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemia
- Trial name
- FIMA (NCT01678183)
- Testing
- Monthly Financial Incentive, Final Financial Incentive
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Boston Medical Center
Diabetes
Novel Type 2 Diabetes Mellitus Preventive Therapies
Over the past two decades, type 2 diabetes mellitus (T2DM) has emerged from relative obscurity to become one of the most serious complications of obesity in Hispanic obese populations, especially among those with a family history…
- Trial name
- NCT02351323
- Testing
- Glutamine (Pharmacological doses), Lifestyle change
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Boston Medical Center
ALL
Massage Therapy Versus Music Therapy Pilot Study
This project studies the feasibility of (1) implementing massage therapy and music therapy onto a busy medical inpatient unit at Boston Medical Center, and (2) evaluating massage therapy and music therapy's impact on patient…
- Trial name
- NCT02227680
- Testing
- Music Therapy, Massage Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Boston Medical Center
Dysphagia
Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer Patients
The purpose of the investigation is to learn whether intense swallowing exercise or intense swallowing exercise coupled with electrical stimulation (E-Stim) helps patients who had head/neck cancer and currently have dysphagia…
- Trial name
- NCT00629265
- Testing
- Neurotech NT2000 Neuromuscular Electrical Stimulation (NMES)
- Where
- 14 sites in United States
- Volunteers
- 170 people
- Sponsor
- Boston Medical Center
Alcohol Dependence, Alcoholism
Addiction Health Evaluation And Disease Management (AHEAD) Study
The objective of this study is to test whether a chronic disease management (CDM) program for substance abusers in primary care leads to improved alcohol and drug-related outcomes (such as reduced consumption and health problems)…
- Conditions
- Alcohol Dependence, Alcoholism, Drug Dependence
- Trial name
- NCT00278447
- Testing
- Chronic Disease Management for substance abuse, Standard care
- Where
- United States
- Volunteers
- 569 people
- Sponsor
- Boston Medical Center
Drug Usage, Drug Abuse
Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use
The objective of this study is to test whether screening and brief intervention for drug use among primary care patients leads to improved drug-related outcomes (such as decreased drug use and consequences).
- Conditions
- Drug Usage, Drug Abuse, Drug Dependence
- Trial name
- ASPIRE (NCT00876941)
- Testing
- Standard Brief Intervention, Enhanced Brief Intervention, Control: Information and Feedback
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- Boston Medical Center
Maternal Depression
Reducing Risk After an Adverse Pregnancy Outcome
This application to the Boston University Medical Center Institutional Review Board outlines a research plan devoted to identifying and managing maternal depression in Early Intervention (EI).
- Trial name
- NCT01182363
- Testing
- Project Solve Education
- Where
- 4 sites in United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Biometrics
Study to Improve Healthy Eating for At-Risk Older Adults
This application, funded by the American Association of Retired Persons(AARP) Foundation, is to implement the Healthy Eating for at Risk Older Adults (HERO) initiative.
- Trial name
- NCT01846169
- Testing
- Food deliveries
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Boston Medical Center
Leukemia, Lymphoma
Ganciclovir Plus Arginine Butyrate in Treating Patients With Cancer or Lymphoproliferative Disorders Associated With the Epstein Barr Virus
RATIONALE: The Epstein Barr virus can cause cancer and lymphoproliferative disorders. Ganciclovir is an antiviral drug that acts against the Epstein Barr virus.
- Conditions
- Leukemia, Lymphoma, Precancerous Condition, Small Intestine Cancer
- Trial name
- NCT00006340
- Testing
- arginine butyrate, ganciclovir
- Where
- 6 sites in United States, France and 2 more
- Sponsor
- Boston Medical Center
Carcinoid Syndrome
Study of Panitumumab in the Treatment of Carcinoid Syndrome
The primary hypothesis of this study is that panitumumab, an inhibitor of the epidermal growth factor receptor (EGFR), is an effective treatment for carcinoid syndrome in people who fail or do not adequately respond to octreotide…
- Trial name
- NCT01172717
- Testing
- Panitumumab
- Where
- 2 sites in United States
- Sponsor
- Boston Medical Center
Depression
Automated Telephone System to Improve Treatment Adherence in People With Depression
This study will determine the efficacy of a computerized telephone system called Telephone-Linked Care (TLC) in improving adherence to antidepressant medication regimens in people with depression.
- Trial name
- NCT00136240
- Testing
- Computer Assisted Education for Behavior Change
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Boston Medical Center
HIV/AIDS
Improving HIV Prevention Skills in People With Serious Mental Illnesses
This study will evaluate the effectiveness of motivational interviewing plus skill building in reducing HIV risk behavior in people with serious mental illnesses.
- Trial name
- NCT00356291
- Testing
- Skill-Building (SB) plus Motivational Interviewing, Skill-Building (SB)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Boston Medical Center
Cardiovascular Disease
Improving Dietary Behavior Through Tailored Messages
The aim of this study is to compare a Web-based system and a computer telephone system to determine their effectiveness in improving diet behaviors compared to each other and a control group.
- Trial name
- NCT01864694
- Testing
- TLC-Diet, WEB-Diet, Assessment-only control
- Where
- United States
- Volunteers
- 1,224 people
- Sponsor
- Boston Medical Center
HIV Infections
HIV Prevention With the Mentally Ill
The purpose of this study is to determine whether motivational interviewing and skills building interventions reduce HIV risk behavior for adults with serious and persistent mental illness.
- Trial name
- NCT00643305
- Testing
- Skills Building with Motivational Interviewing, Skills Building
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Maternal Depression
Supporting the Well Being of Families of Young Children With Autism Spectrum Disorders
The objective of this 2 year research project is to determine whether an evidenced-based empowerment strategy, Problem Solving Education (PSE), targeted to mothers of young children with autism spectrum disorders (ASDs), promotes…
- Trial name
- NCT01021384
- Testing
- Problem Solving Education
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Boston Medical Center
Chronic Disease
Study of PhoneCare System to Treat Patients With Chronic Diseases
The aim of this study is to assess the effectiveness of Telephone-Linked Care for Complex Patients (TLC-C) in the care of patients with complex health care needs.
- Trial name
- ComplexPt (NCT01458184)
- Testing
- PhoneCare system
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Depression
Use of Conversation and Acoustic Signals in Measuring Depression Severity
The purpose of this study is to test a new monitoring technology that uses the sound of a depressed person's speech to assess the severity of depression symptoms.
- Trial name
- NCT00831935
- Where
- 2 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Leukemia
Vaccine Therapy in Treating Patients With Acute Myeloid Leukemia
RATIONALE: Vaccines made from a person's white blood cells and cancer cells may make the body build an effective immune response to kill cancer cells.
- Trial name
- NCT00100971
- Testing
- autologous tumor cell vaccine, therapeutic autologous dendritic cells, tumor cell-derivative vaccine therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Medical Center