Clinical trials: sponsored by Boston Medical Center
Substance Use Disorders, Children of Mothers With Substance Use Disorders
Parenting Intervention for Mothers With Substance Use Disorder
Children of mothers with substance use disorder (SUD) constitute a growing and highly vulnerable population. Evidence-based parenting interventions have the potential to both support parents' recovery and mental health by helping…
- Trial name
- NCT06489522
- Testing
- THRIVE
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Medical Center
Opioid Use Disorder
PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study
The US opioid overdose epidemic has been accompanied by an increase in human immunodeficiency (HIV) among persons who inject drugs.
- Trial name
- CHORUS+ (NCT05769218)
- Testing
- CHORUS+, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 284 people
- Sponsor
- Boston Medical Center
Mental Health Issue, Substance Use Disorders
Co-Active Therapeutic Theatre (Co-ATT) for Dual-Diagnosis Patients
Drama Therapy involves of the use of theatrical techniques (such as script development, acting exercises, improvisation, etc.) to help treat patients' mental illness and improve their functioning and overall sense of wellbeing.
- Trial name
- Co-ATT (NCT06187701)
- Testing
- Co-Active Therapeutic Theatre (Co-ATT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Delirium
Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care
In this pilot study a new kind of music therapy will be created and tested to help prevent confusion, called delirium, that can happen in the hospital.
- Trial name
- DyNamic (NCT07137949)
- Testing
- Music therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Medical Center
Post Operative Complications
The Impact of Prehabilitation
While numerous studies have assessed the promising impacts of prehabilitation, there is a lack of prehabilitation research within lower socioeconomic patient populations.
- Trial name
- Prehab (NCT06181253)
- Testing
- Preoperative education, Moderate aerobic exercise, Text messages
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston Medical Center
Diabetes Mellitus, Type 1, Diabetes Complications
Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes
Minoritized individuals with type 1 diabetes (T1D) have approximately 2% higher average A1c levels and twice the rate of hospitalizations, complications, and mortality as their white counterparts.
- Trial name
- NCT06236607
- Testing
- Device specific training, Study clinician/educator visit
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Boston Medical Center
Hypotensive Anesthesia, Orthognathic Surgery
Hypotensive Anesthesia for Orthognathic Surgery
The overall objective of this double blinded, randomized controlled trial (RCT) is to compare specific outcomes of three medications (Dexmedetomidine, Nicardipine, and Labetalol) which are routinely used to lower blood pressure…
- Trial name
- NCT06093893
- Testing
- Dexmedetomidine, Nicardipine, Labetalol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Boston Medical Center
Respiratory Distress Syndrome
Prehospital Telemedicine Feasibility/Acceptability Pilot
Teleconsultation, or the use of video telecommunications technology to deliver expert recommendations for care remotely, has been used to improve the safety and quality of emergency care for children in hospital-based acute care…
- Trial name
- NCT05967624
- Testing
- Teleconsultation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Boston Medical Center
Post Operative Pain, Opioid Use, Unspecified
Sensory Outcomes in Active Substance Users
The incidence and severity of postoperative pain after spine surgery are notably high, often requiring intensive management and potentially affecting the patient's recovery, satisfaction, and long-term outcomes.
- Trial name
- NCT06639438
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston Medical Center
Communication Research
Adapted Hospital Discharge Intervention: the CONNECT Pilot
Hospital discharge is a dangerous time for patients: one in five will suffer an adverse event, such as a medication error, and nearly 25% will be readmitted within 30 days.
- Trial name
- CONNECT (NCT07032818)
- Testing
- Additional post discharge phone call
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Medical Center
Anxiety, Mental Health Disorder
Preventing Mental Disorders Among Women Internally Displaced by War in Ukraine: The SHAWL Trial
This study is a randomized controlled trial among 120 recently displaced women to determine the effectiveness of a single-session Acceptance and Commitment Therapy (ACT) group therapy on prevention of development of mental health…
- Conditions
- Anxiety, Mental Health Disorder, War-Related Trauma, Acceptance and Commitment Therapy
- Trial name
- SHAWL (NCT06679114)
- Testing
- Acceptance and Commitment Therapy, Attention control
- Where
- Ukraine
- Volunteers
- 120 people
- Sponsor
- Boston Medical Center
Tuberculosis, Malnutrition
Tuberculosis - Learning the Impact of Nutrition
The proposed work is based on the finding that one-third of the world is infected with the bacteria Mycobacterium tuberculosis (Mtb) and only 10% of these individuals develop TB.
- Conditions
- Tuberculosis, Malnutrition, Helminth Infection
- Trial name
- TB-LION (NCT03598842)
- Testing
- Nutritional Supplementation Meal, Multivitamin, Anti-parasitic medications
- Where
- India
- Volunteers
- 786 people
- Sponsor
- Boston Medical Center
Diabetes Mellitus, Type 2
Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships
The goal of this study is to develop, implement, and evaluate a patient-centered triage and referral model designed to improve health outcomes for individuals with uncontrolled type 2 diabetes mellitus (T2DM) and unmet…
- Trial name
- THRIVE-DM (NCT07043426)
- Testing
- THRIVE-DM, Standard of care
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Boston Medical Center
Cardiac Arrest
Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst
Cardiovascular disease remains the leading cause of death in the United States. Mortality rates of cardiac arrest range from 60-85%, and approximately 80% of survivors are initially comatose.
- Trial name
- SPARE (NCT03261089)
- Where
- 8 sites in United States, Brazil
- Volunteers
- 600 people
- Sponsor
- Boston Medical Center
Multiple Myeloma
Collection of Samples and Clinical Data From Patients With Amyloid Diseases
RATIONALE: Collecting and storing samples of blood, urine, tissue and data from patients with amyloid diseases to test in the laboratory may help the study of this disease in the future.
- Trial name
- NCT00898235
- Testing
- clonality analysis, polymerase chain reaction, protein analysis
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Boston Medical Center
Health Behavior
Family Partner Navigation for Children
Family Navigation (FN), an evidence-based care management strategy which is a promising intervention to help low income and minority families access timely mental health services.
- Trial name
- NCT03569449
- Testing
- Usual care, Clinic-based visits, Standard pediatric surveillance
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Boston Medical Center
Tuberculosis, Pulmonary, Undernutrition
The INSTITUT Study Tuberculosis Nutritional Support
Undernutrition is a leading global risk factor of tuberculosis (TB) and a prevalent comorbidity associated with TB. In Benin, the National TB Program systematically provides nutritional support to all persons with TB (PWTB)…
- Trial name
- INSTITUT (NCT06084715)
- Testing
- Nutritional support
- Where
- 2 sites in Benin, Togo
- Volunteers
- 769 people
- Sponsor
- Boston Medical Center
Heart Failure
Haiti Community Health Workers (CHW) Adaptation
Evidence-based interventions to improve linkage and outcomes for heart failure (HF) patients requires input from stakeholders: patients, community health workers (CHWs), healthcare staff, and health system administrators.
- Trial name
- NCT05091710
- Testing
- HF follow up care, HF Standard of Care (SOC)
- Where
- Haiti
- Volunteers
- 30 people
- Sponsor
- Boston Medical Center
Alcohol Use Disorder (AUD)
Records for Alcohol Care Enhancement
Unhealthy alcohol use (the spectrum from risky consumption through alcohol use disorder, AUD) is a leading cause of preventable death in the US (88,424 deaths annually costing $249 billion a year), and alcohol-related health…
- Trial name
- RACE (NCT05492942)
- Testing
- Best Practice Advisory (BPA) and Population Health Management (PHM), Best Practice Advisory (BPA) and Clinical Care Management (CCM), Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Tuberculosis, Pulmonary, Helminthiasis
Tuberculosis - Learning the Effect of Parasites and Reinforcing Diets
The objectives of this research are to determine: the burden of intestinal parasitic infections among persons living with pulmonary tuberculosis (TB) whether intestinal parasitic infections alter TB treatment outcomes, including…
- Conditions
- Tuberculosis, Pulmonary, Helminthiasis, Malnutrition
- Trial name
- TB-LEOPARD (NCT05048485)
- Where
- 2 sites in United States, India
- Volunteers
- 141 people
- Sponsor
- Boston Medical Center