Clinical trials: sponsored by Boston Medical Center
Low-grade Oral Dysplasia
Lactobacillus Lozenges as Preventative Care in Low-grade Dysplasia
There are limited evidence-based management options for patients with low-grade oral dysplasia. Despite the risk of malignant transformation, management is frequently limited to risk factor reduction (such as smoking cessation)…
- Trial name
- NCT05707702
- Testing
- Probiotic oral lozenges, Standard of care for oral dysplasia
- Where
- United States
- Sponsor
- Boston Medical Center
Financial Hardship, Food Insecurity
Economic Mobility Pilot
Research on economic mobility barriers consistently demonstrates that lack of access to jobs that pay living wages and to asset building opportunities coupled with cliff effects across public assistance programs (families losing…
- Conditions
- Financial Hardship, Food Insecurity, Health Status
- Trial name
- NCT05963763
- Testing
- Career Navigator Coaching
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Sickle Cell Disease
Sickle Cell Anemia WE CARE
This mixed-methods study aims to understand the implementation of a previously tested, efficacious social determinants of health (SDoH) screening and referral intervention in the outpatient pediatric hematology setting…
- Trial name
- SCAWECARE (NCT03716726)
- Testing
- WE CARE SDoH Screening Survey, Family Resource Book, Standard of care
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Type 2 Diabetes Treated With Insulin
Novolog vs. Fiasp Insulin in Non-critically Ill Hospitalized Patients With Type 2 Diabetes Mellitus
Hyperglycemia affects 30-40% of hospitalized patients. Despite the fact that basal/bolus insulin therapy has been demonstrated to improve glycemic control and clinical outcomes in patients, achieving good glucose control remains…
- Trial name
- In-FI (NCT04460326)
- Testing
- Insulin glargine, NovoLog, Insulin Fiasp
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Boston Medical Center
HIV, Smoking
Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation
The purpose of this study is to learn how smoking affects the immune systems in people with HIV infection. The investigators would like to know if HIV infected smokers who quit smoking have different responses in their tissues…
- Trial name
- NCT02836067
- Testing
- Counseling, Smoking Cessation drugs, Bronchoscopy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Boston Medical Center
IUD Removal
Intrauterine Device (IUD) Self Removal
This pilot research study will teach patients how to self-remove intrauterine contraceptive device (IUD) through an educational video and simulation and evaluate patient perspectives and experiences related to IUD self-removal…
- Trial name
- NCT05191238
- Testing
- IUD self-removal education
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Boston Medical Center
Alcohol Use Disorder, Alcohol Drinking
Pitolisant Effects on Alcohol Self-Administration in Heavy Drinkers
This is a double-blind, randomized, placebo-controlled, crossover design trial that will test the effect of pitolisant on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT04596267
- Testing
- Pitolisant
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Medical Center
Breast Feeding
Prenatal Breastfeeding Education
In this pilot randomized control trial, the investigators will evaluate the feasibility and acceptability of using a video and website in a prenatal visit to provide breastfeeding education, focusing on how to hand express (HE)…
- Trial name
- NCT04549129
- Testing
- Breastfeeding education video, Breastfeeding website, Usual breastfeed education
- Where
- United States
- Sponsor
- Boston Medical Center
Schizophrenia Spectrum Disorder (SSD)
Virtual Group Fitness and Nutrition Intervention for Individuals With Psychosis
Individuals with schizophrenia spectrum disorder (SSD) often face unique barriers that limit the development of long-lasting lifestyle changes.
- Trial name
- NCT04783246
- Testing
- Group Fitness, Nutrition education
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Boston Medical Center
Hyperglycemia, Postoperative Infection
Hyperglycemia in Neurosurgery
Poor glycemic control is recognized as a risk factor for postoperative infection. For the neurosurgical patient, postoperative infection can lead to devastating complications such as meningitis, encephalitis and death.
- Trial name
- NCT05236751
- Where
- 3 sites in United States, Italy and 1 more
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Diabetes Mellitus, Type 2, Pre Diabetes
Mobile Application to Create Healthy Food Preparation Habits for Patients With Diabetes and Prediabetes
Boston Medical Center (BMC) serves many underserved, low-income patients and has developed an innovative strategy to combat food insecurity including a preventative food pantry, a teaching kitchen, and a rooftop farm that…
- Trial name
- NCT05726409
- Testing
- Mobile application
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Palliative Care
Conversational Agents to Improve Quality of Life in Palliative Care
In this study the investigators will advance research on the development of easy to use technologies to empower patients. This is a scalable approach that has a significant potential to reduce suffering for palliative care…
- Trial name
- ECA-PAL (NCT02750865)
- Testing
- Embodied Conversational Agent (ECA)
- Where
- United States
- Volunteers
- 367 people
- Sponsor
- Boston Medical Center
Aging
Computer Agents to Promote Walking in the Elderly
This proposal is a randomized control trial using innovative interactive health technologies to promote and sustain walking behavior among elderly patients.
- Trial name
- NCT00959712
- Testing
- ECA Interaction
- Volunteers
- 263 people
- Sponsor
- Boston Medical Center
Adhesive Capsulitis
Formal Physical Therapy (PT) vs. Home PT for Adhesive Capsulitis
This study aims to evaluate physical therapy (standard of care) and home exercise vs. home exercise alone for the treatment of adhesive capsulitis.
- Trial name
- NCT03049787
- Testing
- Home Exercise Protocol, Physical Therapy Protocol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
COVID-19
Etoposide in Patients With COVID-19 Infection
This is a randomized, open-label phase II study designed to evaluate the safety and efficacy of etoposide in patients with the 2019 novel coronavirus (COVID-19) infection.
- Trial name
- NCT04356690
- Testing
- Etoposide
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Medical Center
Amyloidosis; Systemic
Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis Patients
This is a single arm, open label study designed to evaluate the safety and efficacy of propylene glycol-free melphalan hydrochloride in patients with AL amyloidosis.
- Trial name
- NCT02994784
- Testing
- Propylene Glycol-Free Melphalan Hydrochloride
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Boston Medical Center
Food Insecurity
Reducing Food Insecurity During COVID-19
This study aims to compare the effectiveness of two interventions to address food insecurity among low-income families with young children during the COVID pandemic.
- Trial name
- NCT04652596
- Testing
- Produce prescription program, Grocery store gift cards
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
HIV Infection, Drug Use
Linking Infectious and Narcology Care-Part II
This study, "Linking Infectious and Narcology Care - Part II (LINC-II)," will implement and evaluate a multi-faceted intervention (LINC-II), via a two-armed randomized controlled trial among 240 HIV-infected PWID in St.
- Trial name
- LINC-II (NCT03290391)
- Testing
- Rapid ART initiation, Pharmacotherapy for opioid use disorder, Strengths-based HIV case management
- Where
- 2 sites in Russia
- Volunteers
- 225 people
- Sponsor
- Boston Medical Center
Psychotic Disorders, Psychosis
Pilot Study of Motivational Interviewing for Loved Ones
The study population for this research will include parents and concerned significant others (PCSO) of individuals experiencing recent (past five years) onset of a psychotic disorder (hereafter referred to as individuals with…
- Conditions
- Psychotic Disorders, Psychosis, Psychotic Episode
- Trial name
- MILO-Pilot (NCT04010747)
- Testing
- Motivational Interviewing for Loved Ones (MILO), Mental Health Services Consultation and Waitlist
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Boston Medical Center
Diabetes Mellitus, Type 2
Re-Engineered Discharge for Diabetes-Computer Adaptive Testing (REDD-CAT)
Over 27 million Americans are diagnosed with Type 2 Diabetes Mellitus (T2DM), and their health outcomes, including hospitalization, emergency department use, and hospital readmission, are largely driven by social determinants…
- Trial name
- NCT03889600
- Testing
- REDD-CAT
- Where
- United States
- Sponsor
- Boston Medical Center