Clinical trials: sponsored by Boston Medical Center
Stress Disorder, Biofeedback
Relaxation Breathing Training for Children
Family-centered Relaxation Breathing Training in the Pediatric Outpatient Clinic: The long term goal is to apply simple, low cost, assistive technologies (heart rate variability [HRV] biofeedback together with mobile health…
- Trial name
- NCT03271086
- Testing
- The StressEraser, Breathe2Relax, Reminder text messages
- Where
- United States
- Sponsor
- Boston Medical Center
Food Insecurity
Fresh Truck Pilot to Reduce Food Insecurity in a Medicaid ACO
This research is a randomized pilot study of an intervention to address food insecurity among intermediate risk Boston Accountable Care Organization (BACO) members receiving primary care at Boston Medical Center (BMC).
- Trial name
- NCT04017624
- Testing
- Fresh Truck with stipend, THRIVE screening and referral
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Child Abuse
A Medical Home-Based Intervention to Prevent Child Neglect in High-Risk Families
Child maltreatment, particularly neglect, disproportionally affects low-income children with special health care needs (CSHCN) and has serious short and long-term consequences.
- Trial name
- NCT02857673
- Testing
- Child Abuse Prevention Problem Solving, Active Control Group
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Medical Center
Protein Feeding in Post-traumatic Injury Patients
Early and Adequate Protein Feeding Post-Traumatic Injury
A randomized, parallel-group, pilot study comparing the effect of the early addition of intravenous protein to enteral feeding as tolerated versus enteral feedings as tolerated alone immediately post traumatic injury.
- Trial name
- EMS (NCT02837861)
- Testing
- Routine Nutritional Support plus supplemental IV amino acids, Routine Nutritional Support
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston Medical Center
Anesthesia, Local
Ice as an Adjunct for Local Anesthesia During Anorectal Surgeries
The purpose of this study is to determine, among patients receiving elective anorectal surgery, does application of ice to the perianal area prior to the procedure, lead to use of decreased amounts of intravenous (IV) anesthesia?…
- Trial name
- NCT04000191
- Testing
- MAC, Perianal ice application
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Adolescent Behavior, Pregnancy Related
A Multi-Component Nutrition Program for Pregnant and Parenting Teens
Improving nutrition during pregnancy is critical for maternal and child health, but even more so among pregnant adolescents. Several studies have shown that poor nutrition and diet quality during pregnancy is related to adverse…
- Conditions
- Adolescent Behavior, Pregnancy Related, Postpartum
- Trial name
- NCT04265690
- Testing
- Cooking classes, Text messages
- Sponsor
- Boston Medical Center
Medical; Abortion, Fetus
Home Follow-up After Medication Abortion
This study aims to evaluate a home follow-up alternative after medication abortion with pregnancy testing and a completion test.
- Trial name
- NCT04304365
- Testing
- Follow-up clinic visit, Text message, Low Sensitivity Pregnancy Test (LSPT)
- Sponsor
- Boston Medical Center
Financial Stress, Maternal Distress
Tax Preparation Pilot
The goal of this study to understand what percentage of families in the pediatric clinic at Boston Medical Center (BMC) currently file taxes and use free tax preparation and would accept and use referral to a free tax preparation…
- Trial name
- NCT04135469
- Testing
- Referral for tax preparation services, Navigator assisted tax preparation services at BMC
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Amyloidosis
Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis
The drugs dexamethasone and bortezomib are both FDA-approved for the treatment of multiple myeloma, a disease very similar to amyloidosis. However, they are currently investigational for the treatment of amyloidosis.
- Trial name
- NCT01083316
- Testing
- Bortezomib, Dexamethasone, Melphalan
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Boston Medical Center
AL Amyloidosis
A Phase I/II Trial of Pomalidomide and Dexamethasone in Subjects With Previously-Treated AL Amyloidosis
This study seeks to enroll patients with AL amyloidosis, for whom treatment with one of the standard melphalan chemotherapy-based regimens is either not recommended or is not their preference.
- Trial name
- NCT01570387
- Testing
- Pomalidomide, Dexamethasone
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Boston Medical Center
Multiple Myeloma
Tandem Autologous Stem Cell Transplantation in Treating Patients With Primary Systemic (AL) Amyloidosis
RATIONALE: Autologous stem cell transplantation may be effective treatment for primary systemic (AL) amyloidosis. PURPOSE: This phase II trial is studying how well tandem (two) autologous stem cell transplantation works in…
- Trial name
- NCT00075621
- Testing
- filgrastim, melphalan, autologous peripheral blood stem cell transplantation
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston Medical Center
Diabetes Mellitus
Women in Control: A Virtual World Study of Diabetes Self-Management
This study evaluates the comparative effectiveness of a diabetes self management (DSM) group medical visit in the virtual world (Second life) verses a face-to-face format, aimed to increase physical activity and improve glucose…
- Trial name
- NCT02726425
- Testing
- Diabetes Self Management Medical Group Visits
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- Boston Medical Center
Air Leak From Lung
Pneumostasis With Use of Bio-absorbable Mesh and Fibrin Sealant in Lung Resection
Prolonged air leak, defined as air leak present 5 days after lung resection, is one of the most common complications after lung resection.
- Trial name
- NCT04317924
- Testing
- Polyglycolic acid felt, Standard of care
- Where
- United States
- Sponsor
- Boston Medical Center
HIV Infection, Alcohol Use
St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene
This study is a randomized controlled trial (RCT) to assess the feasibility, tolerability, and safety of using opioid receptor antagonists (naltrexone and nalmefene) to treat pain among HIV-infected persons with heavy alcohol use…
- Conditions
- HIV Infection, Alcohol Use, Pain
- Trial name
- PETER PAIN (NCT03278886)
- Testing
- Low dose naltrexone, Nalmefene
- Where
- Russia
- Volunteers
- 11 people
- Sponsor
- Boston Medical Center
Surgery, Sedation
Oral Versus Intravenous Sedation for Ocular Procedures
The purpose of this study is to evaluate patient satisfaction after eye surgery when given a capsule compared to an intravenous (IV) dose of sedation (calming medication).
- Trial name
- NCT03246724
- Testing
- Triazolam, Midazolam, Microcrystalline Cellulose
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Boston Medical Center
Wound Heal
Platysma Incision Cosmesis
The anterior cervical fusion and decompression (ACDF) surgery provides direct access to symptomatic areas of the cervical spine.
- Trial name
- NCT03338608
- Testing
- Anterior Cervical Decompression and Fusion, Vertical Platysma Incision, Transverse Platysma Incision
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Smoking Cessation
Hospital-based Patient Navigation and Smoking Cessation
In a pilot randomized controlled trial (RCT), smokers hospitalized on the general internal medicine or family medicine service will be randomized to: 1) enhanced traditional care (ETC), or 2) patient navigation (PN).
- Trial name
- NCT03452371
- Testing
- Patient Navigation, Enhanced Traditional Care
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston Medical Center
Cancer, Smoking Cessation
Mindfulness Based Smoking Cessation Program
This is a study designed to mindfulness based stress reduction (MBSR) training program to assess feasibility and acceptability of the intervention.
- Trial name
- NCT02795312
- Testing
- Smoking Cessation Program
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Boston Medical Center
Hemorrhoid Pain
Post Hemorrhoidectomy Anorectal Pain
This is a quality assurance trial to evaluate the effectiveness of guided breathing exercises on reducing the symptoms of hemorrhoidal disease in colorectal surgery patients.
- Trial name
- NCT03240185
- Testing
- deep breathing exercises
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Scapula Fracture, Glenoid; Fracture
Clinical Outcomes Following Glenoid Neck Fracture as Correlated With Quantitative Assessment of Osseous Injury
A significant subset of patients with scapula fractures also involves the glenoid neck (bone joining the shoulder joint the scapular body).
- Trial name
- NCT00644813
- Testing
- Scapular with glenoid neck fractures
- Where
- 13 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- Boston Medical Center