Clinical trials: sponsored by Boston University
Atopic Dermatitis
Clinic-Based Atopic Dermatitis Therapeutic Patient Education
The primary objective of this randomized trial is to determine whether comprehensive, accessible, and animation-style videos are a more effective method of therapeutic patient education (TPE) based on clinical outcomes than paper…
- Trial name
- AD-TPE (NCT04352270)
- Testing
- AD printed educational materials, AD educational videos
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Boston University
Family Planning
Evaluating the Efficacy of Using a Digital Consumption Management Tool for Family Planning in Zambia
The primary objective of this evaluation is to understand the effectiveness of the OpenSRP platform on unmet family planning (FP) demand in rural Zambia. The specific objectives are to: 1.
- Trial name
- NCT05503992
- Testing
- Intervention package
- Where
- 3 sites in Zambia
- Volunteers
- 2,523 people
- Sponsor
- Boston University
Public Speaking, Speech Anxiety
Virtual Reality Intervention for Speech Anxiety
Exposure-based cognitive behavior therapy is an efficacious treatment for speech anxiety and has been delivered effectively in a virtual reality (VR) environment.
- Trial name
- NCT06086756
- Testing
- Exposure intervention plus positive mood induction, Exposure intervention plus negative mood induction
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Chronic Traumatic Encephalopathy
The DIAGNOSE-CTE Research Project
This is a study to develop methods of diagnosing chronic traumatic encephalopathy (CTE) during life, as well as to examine possible risk factors for this neurodegenerative disease.
- Trial name
- DIAGNOSE-CTE (NCT02798185)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston University
Caries, Dental, Health Behavior
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
This is a randomized clinical trial to test the efficacy of a parent-targeted text message-based intervention program on caries incidence and oral health behaviors (child and parent).
- Trial name
- iSmile (NCT03294590)
- Testing
- OHT Parent targeted text messages, CWT Parent targeted text messages
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Boston University
Preconception Care
Nthabi in Lesotho - Implementation
This project will determine how well the mobile health (mHealth) Nthabi application is introduced and used at district hospitals in Lesotho.
- Trial name
- NCT04354168
- Testing
- mHealth Application
- Where
- Lesotho
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Boston University
Early Childhood Development
Evaluation of Scaling Up Early Childhood Development in Zambia
In Zambia, 40% of children under five years of age are stunted and 6% are wasted. While the Zambian government has focused on child nutrition in recent years, more focus on holistically improving early child development (ECD) is…
- Trial name
- SUpErCDZ (NCT03991182)
- Testing
- SMAGs trained on ECD curriculum, Head women trained on ECD curriculum, Head women led parent groups
- Where
- 3 sites in Zambia
- Volunteers
- 1,108 people, healthy volunteers welcome
- Sponsor
- Boston University
Cigar Smoking
The Impact of Cigarillo Warnings on Purchasing
The purpose of this study is to determine whether different cigarillo warning formats (pictorial, FDA-proposed text-only, current Surgeon General text-only) reduces demand for cigarillos.
- Trial name
- NCT05434013
- Testing
- Cigarillo warnings-Surgeon General Text-Only, Cigarillo warnings-FDA proposed text-only, Cigarillo warnings-Pictorial
- Where
- United States
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- Boston University
Anxiety, Depression
Process-Based Therapy in an Outpatient Setting
The proposed study aims to examine the effects of process-based therapy on 6 adult patients presenting for treatment at a university community outpatient clinic using a nonconcurrent multiple baseline design.
- Trial name
- NCT05105568
- Testing
- Process-based therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Boston University Charles River Campus
Stroke
Effects of Soft Robotic Exosuit on Exercise Capacity, Biomakers of Neuroplasticity, and Motor Learning After Stroke
High intensity exercise is known to improve a person's ability to learn new motor skills. The goal of this project is to evaluate if a robotic exosuit can help people who have had a stroke perform walking rehabilitation at higher…
- Trial name
- NCT05138016
- Testing
- Soft exosuit, No Soft exosuit
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Boston University Charles River Campus
Pain, Chronic, Pain, Musculoskeletal
Assessment of the Efficacy of Digital CBT for Anxiety in Adults With Chronic Musculoskeletal Pain
The present study involves a randomized clinical trial of Digital Cognitive Behavioral Therapy (dCBT) targeting worry and anxiety symptoms in a population with chronic pain and clinical levels of generalized anxiety disorder…
- Conditions
- Pain, Chronic, Pain, Musculoskeletal, Anxiety
- Trial name
- NCT04907656
- Testing
- dCBT
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Boston University Charles River Campus
HIV Infection, Alcohol Consumption
Boston ARCH 4F Intervention to Reduce Fall Risk in People With HIV and Alcohol Use
This study is being conducted to assess the acceptability and feasibility of a randomized trial of a 10 week virtual intervention to reduce fall risk in people with HIV who consume alcohol.
- Conditions
- HIV Infection, Alcohol Consumption, Falls, Accidental, Falls
- Trial name
- NCT04804579
- Testing
- Fall Prevention Intervention
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Boston University
Alcohol Dependence
Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism
Alcoholism is the third leading cause of preventable death in the US, accounting for 80,000 deaths annually. Almost 18 million US adults have alcohol use disorder (AUD); however, approved medications for the treatment of AUD has…
- Trial name
- NCT02901041
- Testing
- Zonisamide, Take Control
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Boston University Charles River Campus
HIV Infections, Alcohol Drinking
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study
The purpose of this study is to follow a cohort of HIV-infected adults who have alcohol and/or drug use to: 1) test the associations between alcohol (and illicit drugs and polypharmacy (multiple prescribed medications)) and falls…
- Conditions
- HIV Infections, Alcohol Drinking, Substance-Related Disorders, Bone Diseases
- Trial name
- NCT03414411
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- Boston University
Tuberculosis, Multidrug-Resistant
Efficacy and Safety of Levofloxacin for the Treatment of MDR-TB
Multi-drug-resistant tuberculosis (MDR-TB) affects nearly 600,000 persons each year around the world. This type of tuberculosis is very difficult to treat, and many patients die from it.
- Trial name
- Opti-Q (NCT01918397)
- Testing
- Levofloxacin, Optimized background regimen (OBR)
- Where
- 3 sites in Peru, South Africa
- Volunteers
- 111 people
- Sponsor
- Boston University
Smoking Cessation
Engaging Working Memory and Distress Tolerance to Aid Smoking Cessation
Specific Aims for this Project Are: 1. To evaluate the ability of two forms of mindfulness training, relative to a control intervention, to engage specific "triple-vulnerability" mechanistic targets that characterize low SES…
- Trial name
- NCT03565497
- Testing
- Wellness Education Control Condition, Mindfulness Training, Mindfulness Training Plus IE
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston University Charles River Campus
Aging
The Entorhinal Cortex and Aerobic Exercise in Aging
The overall goal of this study is to examine how regular exercise affects brain function, spatial memory, and virtual navigation. Participation in this research study will take approximately 4 months.
- Trial name
- ECE (NCT02775760)
- Testing
- Cardiovascular endurance, Strength, balance, and flexibility
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston University
Autistic Disorder
Engaging Siblings of Adults With Autism in Future Planning
The goal of this pilot study was to develop and obtain preliminary feasibility and effectiveness data of a telehealth program (Siblings FORWARD) to help siblings of autistic adults work with their families to plan for the future.
- Trial name
- NCT03374072
- Testing
- Siblings FORWARD program, Information Only Condition
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston University Charles River Campus
PTSD
Effect of D-cycloserine on a Short Imagery Rescripting Intervention for Subclinical PTSD
This study aims to investigate the utility of d-cycloserine (DCS) for enhancing the effect of a novel psychosocial intervention, imagery rescripting (ImRs), in adults with mild to moderate PTSD symptoms after experiencing a…
- Trial name
- NCT03216356
- Testing
- CBT + ImRs, CBT + I.E., D-Cycloserine
- Where
- United States
- Sponsor
- Boston University Charles River Campus
Chronic Low Back Pain, Posttraumatic Stress Disorder
Exercise Maintenance in Chronic Pain and PTSD
The primary purpose of the R21 is using an experimental medicine research approach to study whether a chronic, progressive-based exercise program will help Veterans suffering from chronic low back pain (cLBP) and PTSD achieve…
- Trial name
- NCT03644927
- Testing
- Progressive exercise training, Waitlist Control
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston University