Clinical trials: sponsored by Boston University
Familial Amyloid Polyneuropathy, Familial Amyloidosis
The Effect of Diflunisal on Familial Amyloidosis
The purpose of this study is to determine if diflunisal can prevent progressive lower leg nerve damage in patients with familial amyloidosis polyneuropathy.
- Trial name
- NCT00294671
- Testing
- diflunisal
- Where
- 8 sites in United States, Italy and 3 more
- Volunteers
- 130 people
- Sponsor
- Boston University
Intimate Partner Violence
Study of the Preliminary Effect of TEVAW: a Program to Address Intimate Partner Violence in Northern Tanzania
Women in Tanzania suffer alarming rates of intimate partner violence (IPV) that has detrimental effects on mental and physical health including an increased risk of HIV infection.
- Trial name
- TEVAW (NCT02434796)
- Testing
- Male Peer Groups, Male Peer Groups and Community Dialogues
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcoholism
The Effects of Levetiracetam on Alcohol Dependent Subjects
This study will attempt to examine whether Levetiracetam (Keppra (TM)) can help people with alcohol dependence cut down on their alcohol consumption.
- Trial name
- NCT00325182
- Testing
- Levetiracetam, Historical controls
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University
Irritable Bowel Syndrome
Use of Expressive Writing in Irritable Bowel Syndrome (IBS)
The purpose of this study is to test whether disease-related expressive writing is effective in the treatment of Irritable Bowel Syndrome (IBS).
- Trial name
- NCT01192672
- Testing
- Expressive Writing, Control Writing
- Volunteers
- 197 people
- Sponsor
- Boston University
Depression
Study of Treatments for Depression Among Displaced Adolescents in Northern Uganda.
That interpersonal psychotherapy and creative play therapies can reduce symptoms of depression among adolescents with depressive-type illness in northern Uganda.
- Trial name
- NCT00280319
- Testing
- interpersonal psychotherapy for groups, creative play therapy
- Volunteers
- 338 people
- Sponsor
- Boston University
Obesity
Communicating Risk Information for Obesity
This study will examine the impact of providing genetic risk information for obesity on people's attitudes and beliefs about obesity, health behaviors and weight outcomes.
- Trial name
- NCT01355224
- Testing
- Genetic, Lifestyle
- Where
- United States
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Boston University
Autistic Disorder
Citalopram for Children With Autism and Repetitive Behavior (STAART Study 1)
This study will determine the efficacy and safety of citalopram compared to placebo in the treatment of children with autism.
- Trial name
- NCT00086645
- Testing
- citalopram hydrobromide
- Where
- 6 sites in United States
- Volunteers
- 149 people
- Sponsor
- Boston University
Insulin Resistance
Effect of Salsalate on Bed Rest-Induced Vascular Dysfunction
Physical inactivity induces vascular dysfunction and glucose intolerance during five days of bed rest. This study will investigate the effects of salsalate on these responses.
- Trial name
- NCT00553995
- Testing
- salsalate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston University
Cardiovascular Disease
ROS Signaling in Endothelial Function
The vascular endothelium (inner lining of cells in blood vessels) normally prevents vasospasm and thrombosis by producing nitric oxide and other regulatory substances.
- Trial name
- NCT01037465
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Boston University
Cardiovascular Disease
Effects of Lipemia and Metformin on Endothelial Function
Eating a diet high in fat contributes to the development of atherosclerosis (hardening of the arteries). Acute fat consumption increases levels of fat in the blood and temporarily reduces the ability of blood vessel to dilate…
- Trial name
- NCT01037660
- Testing
- Metformin
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV Infections
Impact of Anti-HIV Treatment on Labor Productivity and Costs in South Africa
The purpose of this study is to determine the impact of anti-HIV treatment on the work attendance of employed people in South Africa.
- Trial name
- NCT00270725
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Vitamin D Deficiency, Hypovitaminosis A
A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice
The goal of this investigator-initiated study is to determine whether the fortification of orange juice with vitamin D, vitamin A, and vitamin E will enhance the vitamin D, vitamin A, and vitamin E status children ages 6-10 that…
- Conditions
- Vitamin D Deficiency, Hypovitaminosis A, Vitamin E Deficiency
- Trial name
- NCT01909063
- Testing
- Vitamin D, Vitamin D, Vitamin E, and Vitamin A, Control, 700 mg Calcium
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston University
Healthy
Evaluation of the Bioavailability of Vitamin D2 in Yeast and Bread
The objective of this study is to test the bioavailability of vitamin D in bread.
- Trial name
- NCT02720575
- Testing
- Consumption of capsule/bread with vitamin D
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
Aphasia, Cerebrovascular Stroke
Transcranial Magnetic Stimulation to Improve Speech in Aphasia
The purpose of this study is to examine whether repetitive transcranial magnetic stimulation (rTMS) can be used to improve speech in chronic stroke patients with aphasia. Aphasia patients can have problems with speech production.
- Trial name
- NCT00608582
- Testing
- Transcranial Magnetic Stimulation, Repetitive
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- Boston University
Tobacco Cessation
Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents
The purpose of this study is to determine whether public housing residents trained in Tobacco Cessation and Motivational Interviewing Techniques to become Tobacco Treatment Advocates(TTA) will be effective in increasing the quit…
- Trial name
- NCT01651611
- Testing
- Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Boston University
Spinal Cord Injuries
My Care My Call: Peer-Led Health Empowerment Training in Chronic Spinal Cord Injury
My Care My Call (MCMC) is an innovative, peer-led telephone intervention designed to empower adults with chronic spinal cord injury (SCI) in the self-management of their primary health care needs to prevent secondary conditions.
- Trial name
- NCT02878070
- Testing
- Calls from a Peer Health Coach for 6 months
- Volunteers
- 86 people
- Sponsor
- Boston University
Alcohol Craving
Quantitative EEG Assessment of Cue-Induced Changes in Brain Activity in Alcohol Use Disorders
Exposure to alcohol related cues, such as the sight of alcoholic drinks, may induce craving for alcohol in drinkers. In this study, the effects of exposure to (1) the pictures of alcoholic drinks and (2) the imagining of a scene…
- Trial name
- NCT01507909
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston University
Cigarette Smoking
Pilot Study of Patient Navigation to Promote Smoking Cessation
Cigarette smoking is a highly significant health threat, responsible for more than 430,000 deaths each year. Low-income persons and racial/ethnic minorities are at particularly high risk, smoking at greater rates and having…
- Trial name
- NCT01414036
- Testing
- Enhanced Traditional Care control, Patient navigation
- Volunteers
- 47 people
- Sponsor
- Boston University
Non-alcoholic Fatty Liver Disease, Fatty Liver
Study of Fish Oil to Reduce ALT Levels in Adolescents
This trial will provide preliminary data to test the hypothesis that a six-month treatment period with fish oil for overweight adolescent with mild to moderate persistent elevation of ALT levels and presence of hepatic steatosis…
- Trial name
- NCT00694746
- Testing
- Omega-3-acid ethyl esters
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston University
Dietary Modification
Theory of Planned Behavior and Implementation Intentions
Diet quality has been associated with a variety of chronic diseases including obesity. One measure that has been studied as an indicator for diet quality is fruit and vegetable intake.
- Trial name
- TPBIIFV (NCT02205697)
- Testing
- Implementation intention
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston University