Clinical trials: sponsored by Boston University
Tuberculosis, Drug-resistant Tuberculosis
Rewards for Tuberculosis Contact Screening
This pilot project is an evaluation of the feasibility, acceptability, and cost of offering an economic reward, in the form of a shopping voucher, to the household contacts of index patients (outpatient drug-susceptible and…
- Trial name
- RECON (NCT02234908)
- Testing
- Contacts, Index
- Where
- 2 sites in South Africa
- Volunteers
- 301 people
- Sponsor
- Boston University
Antiretroviral Therapy, Highly Active, Diabetes Mellitus, Type 2
Non-Communicable Diseases and Antiretroviral Therapy Outcomes in the RapIT Study Population
For national antiretroviral therapy (ART) programs, the most important health system goals in reducing morbidity and mortality among HIV-infection patients are to initiate treatment as early as eligibility criteria allow and to…
- Conditions
- Antiretroviral Therapy, Highly Active, Diabetes Mellitus, Type 2, Cardiovascular Diseases
- Trial name
- RapIT-NCD (NCT02012972)
- Testing
- Referral for NCD care
- Where
- South Africa
- Volunteers
- 354 people
- Sponsor
- Boston University
Pulmonary Hypertension, Sickle Cell Disease
Macitentan in Pulmonary Hypertension of Sickle Cell Disease
This is a pilot study to assess the safety and efficacy of macitentan in patients with pulmonary hypertension of sickle cell disease. This study will enroll approximately 10 subjects.
- Trial name
- MENSCH (NCT02651272)
- Testing
- macitentan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston University
Alcoholic Intoxication, Neurobehavioral Manifestations
Residual Effects of Intoxication on Student Performance
The primary goal of the study is to assess the residual effects of heavy drinking on academic performance. The investigators will also explore whether these effects differ by family history of alcohol abuse and hangover symptoms…
- Trial name
- NCT00183170
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Boston University
Atopic Dermatitis
Monitoring Of Scratch Via Accelerometry In Children
Sleep sensors, wrist worn accelerometers, polysomnography (PSG), and associated data analysis platforms would provide quantitative and qualitative knowledge regarding the action of scratching and sleep quantity in a symptomatic…
- Trial name
- MOSAIC (NCT03873220)
- Testing
- Wrist Actigraphy Devices, Sleep Monitor, Polysomnography
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston University
Mental Illness
Vocational Empowerment Photovoice (VEP)
The purpose of this project is to evaluate a promising peer-run psycho-educational group intervention titled "Vocational Empowerment Photovoice (VEP)" that aims to empower individuals with the most disabling psychiatric…
- Trial name
- VEP (NCT02784938)
- Testing
- Vocational Empowerment Photovoice (VEP)
- Where
- 3 sites in United States
- Volunteers
- 147 people
- Sponsor
- Boston University Charles River Campus
Mental Illness, Social Isolation
Bridging Community Gaps Photovoice
The purpose of this study is to test a peer-led intervention intended to promote the community living and participation of individuals with psychiatric disabilities entitled "Bridging Community Gaps Photovoice" (BCGP).
- Trial name
- BCGP (NCT03291717)
- Testing
- Bridging Community Gaps Photovoice (BCGP)
- Where
- 4 sites in United States
- Volunteers
- 197 people
- Sponsor
- Boston University Charles River Campus
Sepsis
Zambia Chlorhexidine Application Trial
This will be a cluster-randomized controlled trial to assess whether washing the umbilical cord with a disinfectant (4% chlorhexidine) helps to reduce neonatal deaths in Zambia when compared to the current standard of care, dry…
- Trial name
- ZamCAT (NCT01241318)
- Testing
- Chlorhexidine gluconate (4%), Dry cord care
- Where
- Zambia
- Volunteers
- 77,535 people, healthy volunteers welcome
- Sponsor
- Boston University
Lung Cancer Screening, Smoking Cessation
Inpatient Smokers and LDCT Screening Part 2
Lung cancer suffers from large racial and socioeconomic disparities. Yet those at the highest risk of lung cancer death - current smokers, blacks, and individuals with low socioeconomic status (SES) and negative social…
- Trial name
- NCT03793894
- Testing
- Smoking Cessation Counseling, Decision Aid, Shared decision making (SDM)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Boston University
HIV/AIDS, Chronic HIV Infection
Life Plans Intervention Study
The mass provision of HIV treatment in rural KwaZulu-Natal, South Africa has raised adult life expectancy by 18 years since 2003.
- Conditions
- HIV/AIDS, Chronic HIV Infection, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03215901
- Testing
- A Beautiful Future Video, Active Control Video
- Where
- South Africa
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Boston University
Orthognathic Surgery
Bupivacaine Liposomal Injectable Suspension, Pain and Narcotic Use After Elective Orthognathic Surgery
This research is being done to determine quantitative and qualitative differences in patients' post-operative pain levels following elective orthognathic surgery after the local administration of a liposomal bupivacaine…
- Trial name
- NCT03318757
- Testing
- Bupivacaine Extended Release Liposome Injection, Bupivacaine HCl
- Where
- United States
- Sponsor
- Boston University
Vitamin D Deficiency, Fat Malabsorption
25-Hydroxyvitamin D Pharmacokinetic Study
To evaluate the pharmacokinetic parameters of orally administered 25-hydroxyvitamin D3 [25(OH)D3] and vitamin D3 from the corresponding serum concentration-time curves in healthy adults and adults with a history of intestinal…
- Trial name
- NCT03401541
- Testing
- Calcifediol, Calciferol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boston University
Obsessive Compulsive Disorder
Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder
This experiment will examine if the use of computerized tasks that train individuals to control their attention more effectively will predict individual differences in obsessive-compulsive symptoms, rumination and BDNF change.
- Trial name
- CCT-OC (NCT01414023)
- Testing
- Cognitive Control Training, Peripheral Vision Task
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Cardiovascular Disease, Diabetes Type II
Evaluation of Novartis Access; a Non-communicable Disease (NCD) Access Initiative
Countries throughout the world are facing a growing non-communicable disease (NCD) burden. In developing countries, medicines to treat NCDs are often difficult to access or too expensive for many households.
- Conditions
- Cardiovascular Disease, Diabetes Type II, Breast Cancer, Asthma
- Trial name
- NCT02773095
- Testing
- Novartis Access
- Volunteers
- 966 people
- Sponsor
- Boston University
Aging
Physical Activity and Cognition Study
The goal of this research study is to examine whether an intervention to increase physical activity using a body-worn sensor affects cognitive (thinking) processes.
- Trial name
- CTSI (NCT02773121)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boston University
Mental Disorders
Testing Effectiveness of a Peer-Led Intervention to Enhance Community Integration
We are conducting a randomized clinical trial (RCT) comparing the 10-week peer-led Photovoice program to services as usual (SAU) at a large publicly funded community mental health agency in Massachusetts.
- Trial name
- Photovoice (NCT02508480)
- Testing
- Photovoice, Enhanced Control
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Boston University Charles River Campus
Parkinson Disease
Bio Electro Stimulation Therapy for Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction and non-motor symptoms. Here, the investigators propose in a pilot device feasibility trial to examine whether "Bio Electro Stimulation…
- Trial name
- BEST (NCT03014050)
- Testing
- e-Tapper TT-R1
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Boston University
Anxiety Disorders, Depressive Disorder
Testing Psychosocial Treatment Planning Methods for Youth Anxiety and Depression
Youth depression and anxiety represent a serious public health concern, with affected youth often experiencing social, familial, and academic impairment.
- Trial name
- NCT03610373
- Testing
- Modular Approach to Therapy for Children (MATCH)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorders
Investigating Phenotypic Profiles of Children and Adolescents With ASD
The purpose of this study is to provide a detailed description of language and cognitive profiles found among children and adolescents diagnosed with autism spectrum disorders (ASD).
- Trial name
- Phenotyping (NCT02700113)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorders
Brain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder
The main goal of our study is to find out why some people with Autism Spectrum Disorder (ASD) do not develop verbal abilities or remain minimally-verbal throughout adolescence and adulthood.
- Trial name
- BSL (NCT02700074)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus