Clinical trials: sponsored by Boston University
Obesity
A Community-based Study to Target Childhood Obesity
The purpose of this study is to determine the efficacy of a community-based behavioral intervention (H2GO!) on decreasing sugar-sweetened beverage consumption and promoting water consumption among school-aged youth and…
- Trial name
- NCT02890056
- Testing
- H2GO!
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Boston University
Depression, Anxiety
AWARE Intervention: Feasibility and Efficacy Trial at Three University Health Services Centers
The goal of this study is to test the efficacy and the feasibility of the Asian Women's Action for Resilience and Empowerment (AWARE) intervention, in the real world setting -- student health service centers at Boston University…
- Conditions
- Depression, Anxiety, PTSD, Suicidal Ideation
- Trial name
- NCT03961633
- Testing
- AWARE intervention
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Boston University Charles River Campus
Tooth, Nonvital
Endodontic Regenerative Procedure for Immature Non-vital Teeth
In this clinical trial the investigators will evaluate an alternate treatment option, which was developed for teeth with incomplete roots, called Regenerative Endodontic Procedure (REP).
- Trial name
- NCT03425123
- Testing
- Regenerative Endodontic Procedure (REP)
- Where
- United States
- Sponsor
- Boston University
Chronic Disease
Self-Management Using Text Messaging in a Homeless Population
The purpose of this study is to determine if an automated text message intervention is beneficial for homeless patients in reducing their hospital visits, increasing their primary care appointments, and help them increase…
- Trial name
- NCT03034993
- Testing
- Text Messaging
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Boston University
Schizophrenia, Schizoaffective Disorder
Understanding How Cognitive Remediation Works
This study is aimed at evaluating whether the computer-based cognitive exercises in the Thinking Skills for Work (TSW) program are critical to improving work and cognitive outcomes in consumers with serious mental illness and…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Chronic Mental Disorder, Major Depression
- Trial name
- Cog-2 (NCT01683539)
- Testing
- The Thinking Skills for Work Program, The Cognitive Skills for Work Program
- Where
- 2 sites in United States
- Volunteers
- 203 people
- Sponsor
- Boston University Charles River Campus
Social Anxiety Disorder
Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia
This study will assess the effectiveness of D-cycloserine combined with cognitive-behavior therapy in treating people with social anxiety disorder.
- Trial name
- NCT00515879
- Testing
- D-cycloserine, Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Boston University Charles River Campus
Parkinson Disease
eOnOff - D1 Extension
Clinical assessments can only offer a snapshot of daily life with Parkinson's Disease, while wearable devices can offer immensely more information that can improve the understanding of this disease.
- Trial name
- NCT03247387
- Testing
- MC10 BioStampRC, APDM actigraphy device, GENEActiv watch
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Boston University
Osteoarthritis of the Knee
Can Computer-based Telephone Counseling Improve Long-term Adherence to Strength Training in Elders With Knee OA?
The purpose of this research is to determine whether computer-based telephone counseling will improve adherence to strength training in a population of elders with knee osteoarthritis.
- Trial name
- BOOST (NCT01394874)
- Testing
- TLC
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston University Charles River Campus
Posttraumatic Stress Disorder
Written Exposure Therapy for Posttraumatic Stress Disorder
Although evidence-based treatments for PTSD exist, a significant minority of individuals do not benefit from these treatments and many individuals to not seek treatment, citing barriers such as time commitment and expense of…
- Trial name
- WET (NCT01800773)
- Testing
- Written Exposure Therapy, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV
Rapid Initiation of Antiretroviral Therapy to Promote Early HIV/AIDS Treatment in South Africa (RapIT Study)
One of the most serious challenges facing antiretroviral therapy (ART) programs for HIV/AIDS in resource-constrained settings is the failure of ART-eligible patients to complete the steps required to initiate treatment.
- Trial name
- RapIT (NCT01710397)
- Testing
- Rapid ART initiation
- Where
- 2 sites in South Africa
- Volunteers
- 531 people
- Sponsor
- Boston University
Emotional Disorders, Anxiety Disorders
A Unified Treatment for Anxiety Disorders
The purpose of this study is to develop a new psychological therapy for a variety of different types of emotional disorders. The study will compare symptoms and functioning of clients who receive the treatment with those who do…
- Trial name
- NCT00586001
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Volunteers
- 37 people
- Sponsor
- Boston University Charles River Campus
Mental Illness, Social Isolation
"Recovery 4 US" - A Photovoice-based Social Media Program
This study is a randomized trial evaluating "Recovery 4 US", a social media program aimed at the enhancement of community participation and overall recovery of individuals with psychiatric disabilities.This innovative e-mental…
- Conditions
- Mental Illness, Social Isolation, Loneliness
- Trial name
- R4US (NCT03266614)
- Testing
- Recovery 4 Us
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Boston University Charles River Campus
HIV
Improving ART Retention and Adherence in Uganda: The WiseMama Study
WiseMama is designed to improve our understanding of interventions that are feasible and effective in helping HIV-positive pregnant and postpartum women to maintain high adherence to antiretroviral medications.
- Trial name
- WiseMama (NCT02396394)
- Testing
- Two-Step Adherence Feedback
- Where
- Uganda
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Boston University
Major Depressive Disorder
Improving Therapeutic Learning in Depression: Proof of Concept
Despite advances in both pharmacotherapy and psychotherapy for major depression, non-response and partial-response remain relatively common outcomes, motivating the search for new treatments.
- Trial name
- NCT02376257
- Testing
- 250 mg DCS, 100 mg Modafinil
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Boston University Charles River Campus
Peripheral Arterial Disease
Clinical Utility of Endothelial Dysfunction in PAD
This study will seek to determine whether non-invasive measures of endothelial function have utility as surrogate markers of cardiovascular risk in patients with peripheral arterial disease undergoing vascular surgery.
- Trial name
- NCT00491751
- Testing
- atorvastatin, ascorbic acid
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Boston University
Healing of Extraction Socket
The Impact of a Known Bioactive Agent on the Resolution of Alveolar Socket Preservation
The advent of endosseous implant restoration has driven an increasing need for alveolar bone preservation and/or augmentation strategies.
- Trial name
- NCT02802436
- Testing
- Extraction with socket graft
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Health Behaviors
Assessment of the Predictors and Moderators of Health Behavior Change
This study will investigate three interventions-values clarification, planning, or combined (values clarification + planning)-for increasing goal-consistent health behavior (e.g., exercise or dieting).
- Trial name
- ABC3 (NCT03139656)
- Testing
- Values Clarification, Planning, Combined
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Schizophrenia, Schizoaffective Disorder
Exercise and Cognitive Training
The purpose of this study is to evaluate the potential benefits of combining cognitive remediation and exercise in improving cognitive functioning and response to psychiatric rehabilitation.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT02326389
- Testing
- Exercise, Cognitive Remediation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston University Charles River Campus
Substance-Related Disorders
Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use
This study examines whether isolated doses of d-cycloserine enhance the efficacy of an exposure-based cognitive-behavioral treatment for chronic and treatment refractory substance dependence.
- Trial name
- NCT00430573
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston University Charles River Campus
Scleroderma, Systemic Sclerosis
IL1-TRAP, Rilonacept, in Systemic Sclerosis
Scleroderma,also known as systemic sclerosis (SSc), is a multisystem disease affecting skin and other tissues including joints, muscles, lungs, the gastrointestinal tract and kidneys and tissue fibrosis is widespread.
- Conditions
- Scleroderma, Systemic Sclerosis, Diffuse Scleroderma, Diffuse Systemic Sclerosis
- Trial name
- NCT01538719
- Testing
- Rilonacept
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Boston University