Clinical trials: sponsored by Boston University
Coronary Artery Disease
Effect of Ile-Pro-Pro (IPP) on Endothelial Function in Patients With Coronary Artery Disease
This study will investigate whether the lacto-tripeptide Ile-Pro-Pro (IPP) improves the function of the endothelium in patients with coronary artery disease. The study has a crossover design.
- Trial name
- NCT00924157
- Testing
- IPP
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Boston University
Obesity
Evaluating the Link Between Neighborhood Environments and Obesity Among African American Women
African American women have higher rates of obesity than women of any other racial or ethnic group in the United States. Obesity can have many causes, including genetic and environmental factors.
- Trial name
- NCT00356707
- Where
- United States
- Volunteers
- 23,000 people, healthy volunteers welcome
- Sponsor
- Boston University
Early Pregnancy Failure, Miscarriage
MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure
The purpose of this study is to compare two combinations of drugs (mifepristone and misoprostol versus placebo and misoprostol) used for medical treatment for early pregnancy failure.
- Conditions
- Early Pregnancy Failure, Miscarriage, Fetal Demise, Anembryonic Pregnancy
- Trial name
- MiMi (NCT00468299)
- Testing
- Mifepristone and misoprostol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boston University
Intrauterine Device Expulsion, Medical Abortion
Insertion of an Intrauterine Device (IUD) After Medical Abortion
The purpose of this study is to determine the expulsion and continuation rate of an intruterine device (IUD) placed immediately after medical abortion.
- Conditions
- Intrauterine Device Expulsion, Medical Abortion, Induced Abortion
- Trial name
- NCT00621543
- Testing
- IUD insertion [Copper T-380A or Levonorgestrel (intrauterine system) IUS]
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Boston University
Abortion, Induced
Pilot Study of the Addition of Osmotic Dilators to Preparation Prior to Labor Induction Abortion
One the day prior to medical abortion (labor induction) in the second trimester, insertion of osmotic dilators is added to the routine procedures.
- Trial name
- DAIS (NCT00855842)
- Testing
- osmotic dilator insertion
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston University
Secondhand Smoking
Secondhand Smoke Exposure Reduction Study
The high prevalence of smoking in adults in many developing countries (e.g. in China, 61% among men and 7% among women) results in many children being exposed to secondhand smoke (SHS).
- Trial name
- NCT01145794
- Testing
- smoking hygiene intervention
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Boston University
Secondhand Smoke Exposure, Respiratory Illness
Secondhand Smoke Exposure Reduction Among Young Children in China
Second hand smoking (SHS) is a health hazard to infants and children, in whom it is associated with lower respiratory tract infections, wheezing, cough, middle ear infections and sudden infant death syndrome.
- Conditions
- Secondhand Smoke Exposure, Respiratory Illness, Smoking Cessation
- Trial name
- China SHARE (NCT00995254)
- Testing
- SHI counseling
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Boston University
Vertigo
Diagnosis Of Vertigo With New Imaging
The purpose of this study is to determine the potential usefulness of new functional MRI in diagnostic assessment of patients presenting with vertigo.
- Trial name
- NCT00593216
- Testing
- Functional MRI imaging
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Boston University
Diffuse Cutaneous Systemic Sclerosis
Mycophenolate Mofetil in Systemic Sclerosis
This is a research study of an investigational product called Mycophenolate mofetil (MMF). The study is designed to establish the safety and potential benefit of MMF.
- Trial name
- NCT00433186
- Testing
- Mycophenolate Mofetil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston University
Ectasia
Laser Treatment Of Vascular Lesions On Vocal Cords
Small vascular malformations (SVM) on the vocal fold is a common problem that can disturb the voice. The pulsed dye laser (PDL) has been successfully used for treatment of blood vessel abnormalities in surface tissue, through its…
- Trial name
- NCT00592644
- Testing
- Pulse Dye laser (PDL), CO2 laser or other traditional surgeries
- Volunteers
- 7 people
- Sponsor
- Boston University
Mortality
Lufwanyama Neonatal Survival Project
We seek to determine whether we can reduce day 28 mortality in Zambian newborns by training traditional birth attendants a modified version of the neonatal resuscitation protocol (NRP) and by improving their abiltiy to identify…
- Trial name
- LUNESP (NCT00518856)
- Testing
- Neonatal resuscitation protocol, Standard of care
- Volunteers
- 3,559 people, healthy volunteers welcome
- Sponsor
- Boston University
Type 2 Diabetes Mellitus
Pilot Study Of The Effects Of Resveratrol On Endothelial Function In Subjects With Type 2 Diabetes Mellitus
Observational studies have shown that consumption of grapes and grape products such as red wine is associated with reduced cardiovascular risk. The mechanisms accounting for this benefit remain incompletely understood.
- Trial name
- NCT01038089
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Boston University
Alcoholism
The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects
This investigation will assess the effectiveness of topiramate in reducing ethanol consumption by alcohol dependent subjects. It also will seek to establish whether topiramate can be safely used in this population including…
- Trial name
- NCT00329407
- Testing
- Topiramate (Topamax)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
Pneumonia, Malaria
Zambia Integrated Management of Malaria and Pneumonia Study
The purpose of the study is to demonstrate the effectiveness and feasibility of community-based management of pneumonia and malaria by community health workers (CHWs) in a rural district of Zambia.
- Trial name
- ZIMMAPS (NCT00513500)
- Testing
- Coartem and amoxicillin, Coartem
- Where
- Zambia
- Volunteers
- 3,125 people
- Sponsor
- Boston University
Alcoholism
The Effects of Zonisamide on Alcohol Dependence
In this study the influence of zonisamide administration over a 13 week period on alcohol consumption in alcoholic (alcohol dependent) subjects will be examined.
- Trial name
- NCT00406692
- Testing
- Zonisamide
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Boston University
Coronary Artery Disease
Effects of Almonds On Endothelial Function In Patients With Coronary Artery Disease
The vascular endothelium (inner lining of cells in blood vessels) normally prevents vasospasm and thrombosis by production of a variety of regulatory substances, including nitric oxide.
- Trial name
- NCT01038362
- Testing
- NCEP Step 1 diet plus Almonds, No Almonds
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Boston University
Coronary Artery Disease
Effect of Cranberry Juice on Endothelial Function
A pilot study of 15 subjects will be completed to determine whether acute consumption of cranberry juice has an effect on endothelial function.
- Trial name
- NCT00553904
- Testing
- Cranberry juice
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston University
Coronary Artery Disease
Effect of Grape Seed Extract Plus Ascorbic Acid on Endothelial Function
A pilot study of 15 subjects will be conducted to confirm an acute effect of grape seed extract on endothelial function. We then will perform a a randomized, double blind, placebo controlled crossover study designed to…
- Trial name
- NCT00554242
- Testing
- Grape seed extract and ascorbic acid
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston University
Hypertension
Blood Pressure Lowering Effects of Grape Juice
Recent studies suggest that a diet rich in fruit and vegetables can lower blood pressure, and a number of lines of evidence suggest that grape products may have such an effect.
- Trial name
- NCT00302809
- Testing
- Concord Grape Juice
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston University
Abortion, Induced, Abortion, Second Trimester
A Pilot Study of Priming Before Induction Termination of Pregnancy
Induction termination of pregnancy (second trimester abortion) has a median time of 14 hours from the start of medication (misoprostol) to expulsion of the fetus.
- Trial name
- NCT00495560
- Testing
- Addition of misoprostol 25 mcg 12 hours before induction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boston University