Clinical trials: sponsored by Boston University
Cerebral Palsy
Enhancing Motor Learning in Children With Cerebral Palsy Using Transcranial Direct-current Stimulation
The goal of this study is to test the effects of transcranial direct current stimulation (tDCS) on motor learning and brain plasticity in children with unilateral spastic cerebral palsy (USCP).
- Trial name
- NCT04725019
- Testing
- active transcranial direct current stimulation, Motor training
- Sponsor
- Boston University Charles River Campus
Intellectual Disability, Variable
A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities
This randomized clinical trial is an innovative pilot project to determine the acceptance and impact of telehealth visits on youth with intellectual and developmental disabilities (IDD), their caregivers, and dentists.
- Trial name
- NCT06710483
- Testing
- Pre-Dental Telehealth (PDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Stroke, Old Age
Responders to Rhythmic Auditory Stimulation in Individuals Post-Stroke and Older Adults
Stroke is among the leading causes of long-term disability worldwide. Post-stroke neuromotor impairments are heterogeneous, yet often result in reduced walking ability characterized by slow, asymmetric, and unstable gait…
- Trial name
- NCT06085248
- Testing
- Subject-specific optimized RAS, Active walking
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Stroke
Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke
Stroke survivors often experience impaired neuromechanical control that limits walking speed and quality, particularly due to deficits in paretic propulsion.
- Trial name
- NCT07218094
- Testing
- Walking with robotic ankle assistance
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston University Charles River Campus
Osteoarthritis, Knee
Positive Minds Strong Joints for Knee Osteoarthritis
The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).
- Trial name
- PMSJ (NCT06493903)
- Testing
- Positive Minds, Strong Joints
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Boston University Charles River Campus
First Episode Psychosis (FEP)
Enhancing Cognitive and Work/School Outcomes in First Episode Psychosis Using Cognitive Self-Management Strategies
The goal of this pilot cluster randomized trial is to understand if adding a standardized cognitive self-management program, Thinking Skills for Work-Cognitive Self-Management Strategies (CSM) to Coordinated Specialty Care…
- Trial name
- NCT07749105
- Testing
- Thinking Skills for Work-Cognitive Self-Management Program (CSM), Treatment as Usual (TAU)
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Traumatic Brain Injury
Self-Management Training Among Individuals With TBI
Traumatic brain injury (TBI) can have long-term and chronic effects on an individual's physical, social, and emotional health, impacting quality of life and the ability to engage in meaningful life roles.
- Trial name
- NCT07741149
- Testing
- Participants will be referred to a community based self-management training program
- Volunteers
- 85 people
- Sponsor
- Boston University Charles River Campus
Anxiety Disorders and Symptoms, Depressive Symptoms
Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions
Digital mental health interventions are a cost-effective and efficient approach to expanding the accessibility and impact of psychological treatments; however, little guidance exists for selecting the most effective program for a…
- Trial name
- NCT05567640
- Testing
- The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP), Space for depression, Space for resilience
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Smoking
Attentional Training for Smoking Cessation Via Handheld Device or Personal Computer
Several studies indicate that cigarette smokers show an attentional bias for cigarette-related cues, meaning that they more quickly detect and attend to and have more difficulty disengaging in cigarette-related information than…
- Trial name
- NCT01458834
- Testing
- Attention bias modification task, Control Condition
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Stress
Imaging Cerebral and Sub-cerebral Correlates of Meditative States
Three groups of subjects are trained to practice mindfulness meditation, compassion meditation, or attend a health training control class.
- Trial name
- calm (NCT01262404)
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
HIV, Chronic Pain
Telehealth for Pain and Unhealthy Drinking Among PLWH
This randomized controlled trial is a between-groups design to compare the Motivational and Cognitive Behavioral Management for Alcohol and Pain (MCBMAP) Intervention to a Brief Advice and Information Control condition.
- Conditions
- HIV, Chronic Pain, Unhealthy Alcohol Use
- Trial name
- NCT05503173
- Testing
- MCBMAP, Brief Advice and Information
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- Boston University
Alcohol Use, Unspecified, Relationship, Social
Whole Selves User Testing and Feasibility Study
Whole Selves is a novel print and online intervention using motivational interviewing principles and personalized feedback to address young adults' alcohol use and romantic relationship functioning.
- Conditions
- Alcohol Use, Unspecified, Relationship, Social, Depression, Anxiety
- Trial name
- NCT06392542
- Testing
- Whole Selves
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Boston University
Healthy Volunteers
Assessing the Feasibility of a Novel Dynamometry Protocol for Measuring Finger Extensor Strength
This study aims to evaluate the feasibility and reliability of a novel method for assessing finger extension strength using an adapted dynamometer, addressing the limitation of current hand grasp assessment protocols that focus…
- Trial name
- NCT07730008
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Procedural Anxiety, Procedural Pain
Oral Surgery Virtual Reality Glasses Study
The goal of this randomized trial is to investigate if using virtual reality (VR) glasses for patients who require non-emergent oral surgery procedures under intravenous (IV) sedation improves their overall experience compared to…
- Trial name
- NCT06723158
- Testing
- Virtual reality (VR) glasses with relaxation module
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Boston University
Epilepsy Intractable
Neural Mechanisms of Spatial Representations Beyond the Self
Spatial navigation is a fundamental human behavior, and deficits in navigational functions are among the hallmark symptoms of severe neurological disorders such as Alzheimer's disease.
- Trial name
- NCT05406349
- Testing
- Self-navigation task, Observation task
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Healthy
Imaging Brain Fluids During Breathing
This study will perform magnetic resonance imaging (MRI) measurements of hemodynamics and cerebrospinal fluid flow across breathing tasks and during breath-locked neuromodulation.
- Trial name
- NCT05180981
- Testing
- Transcutaneous vagal nerve stimulation, Breathing task
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Major Depression
Neuroimaging Sleep and Mood in Depression
This study will investigate how sleep and mood are related in patients with depression and in healthy controls. It will use MRI-based measures of brain function to determine how neural systems are modulated by sleep and sleep…
- Trial name
- NCT05497414
- Testing
- Sleep deprivation
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Deployment
Strong Families Strong Forces: Supporting Active Duty Families With Very Young Children
The purpose of this research is to evaluate the efficacy of the Strong Families Strong Forces Parenting Program compared to a parental self-care (Strong Parents) condition in a sample of 150 Active Duty Families with children…
- Trial name
- NCT03045159
- Testing
- Strong Families Strong Forces, Strong Parents
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Stuttering, Developmental, Aphasia, Primary Progressive
Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech
Persistent developmental stuttering affects more than three million people in the United States, and it can have profound adverse effects on quality of life.
- Trial name
- NCT05437159
- Testing
- Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords
- Where
- 3 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus