Clinical trials: sponsored by Boston University
Anxiety Disorders, Depressive Disorder
Flourishing and Virtue in Cognitive-Behavioral Therapy for Anxiety and Depressive Disorders
This two phase study is testing an online version of a transdiagnostic, cognitive behavioral therapy, against a modified version of that therapy emphasizing positive affect.
- Trial name
- NCT05120232
- Testing
- Unified Protocol, Modified Unified Protocol (UP+)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Boston University Charles River Campus
Aphasia, Acquired
Conversation Group Treatment for Aphasia: Does it Work?
The proposed research will test the efficacy of group conversation treatment for people with aphasia and explore whether the effects of treatment differ as a result of the following factors: 1.
- Trial name
- NCT05113160
- Testing
- Conversation Treatment for Aphasia
- Where
- 3 sites in United States
- Volunteers
- 162 people
- Sponsor
- Boston University Charles River Campus
Drinking, College, Drinking Heavy
College Student Daily Life and Alcohol Use Study
Heavy alcohol use among college students is associated with a range of negative consequences. However, college students rarely seek resources or treatment to change their alcohol use.
- Trial name
- NCT06365125
- Testing
- eCHECKUP TO GO, Text messaging boosters
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Knee Osteoarthritis
Telehealth Exercise and Mindfulness for Pain in Osteoarthritis
This is a parallel-arm mixed-methods randomized controlled trial to investigate the feasibility of telehealth delivered mindful exercise vs. usual exercise interventions for people with knee osteoarthritis.
- Trial name
- TEMPO (NCT05524116)
- Testing
- Mindful Exercise program, Exercise
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
HIV, Antiretroviral Therapy
Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-South Africa
In its 2017 revision of the global guidelines for HIV care and treatment, the World Health Organization called for rapid or same-day initiation of antiretroviral treatment (ART) for eligible patients testing positive for HIV.
- Trial name
- SPRINT-SA (NCT04170374)
- Testing
- Routine medical record data collection, Interviews with service providers
- Where
- South Africa
- Volunteers
- 831 people
- Sponsor
- Boston University
HIV, Antiretroviral Therapy
Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-Malawi
In its 2017 revision of the global guidelines for HIV care and treatment, the World Health Organization (WHO) called for rapid or same-day initiation of antiretroviral treatment (ART) for eligible patients testing positive for…
- Trial name
- SPRINT-Malawi (NCT04468399)
- Testing
- Routine medical record data collection, Interviews with service providers
- Where
- 2 sites in Malawi, South Africa
- Volunteers
- 1,781 people
- Sponsor
- Boston University
HIV, Antiretroviral Therapy
Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-Zambia
In its 2017 revision of the global guidelines for HIV care and treatment, the World Health Organization (WHO) called for rapid or same-day initiation of antiretroviral treatment (ART) for eligible patients testing positive for…
- Trial name
- SPRINT-Zambia (NCT04470011)
- Testing
- Routine medical record data collection, Interviews with service providers
- Where
- 2 sites in South Africa, Zambia
- Volunteers
- 2,189 people
- Sponsor
- Boston University
Alcohol Drinking, Chronic Pain
Alcohol Use and Chronic Pain Among Primary Care Patients
Chronic pain and unhealthy drinking are common co-occurring conditions among patients presenting to primary care. Given their impact on functioning and medical outcomes, there would be considerable benefit to developing an…
- Trial name
- NCT04958200
- Testing
- mhealth-pc for alcohol and pain, Treatment As Usual
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Boston University Charles River Campus
Child Development
Zambia Infant Cohort Study - Brains Optimized for Surviving and Thriving
Children exposed to HIV in-utero but uninfected (CHEUs) number 14.8 million globally. In Zambia, an estimated 56,000 CHEUs are born annually, a staggering fraction of the national birth cohort.
- Trial name
- ZICS-BOOST (NCT05119959)
- Testing
- ECD intervention for CHEUs, Usual care for CHEUs
- Where
- 2 sites in United States, Zambia
- Volunteers
- 469 people
- Sponsor
- Boston University
Vitamin D Deficiency, Vitamin D Insufficiency
Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status
The aim of this study is to evaluate the safety and effectiveness of the SOLIUS System in improving serum levels of 25-hydroxyvitamin D in vitamin D deficient/ insufficient adults of various skin types.
- Trial name
- NCT04780776
- Testing
- UVB treatment
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Boston University
Knee Osteoarthritis
Wearable Sensors in Knee OA
This is a single-arm clinical trial to investigate the outcome of exercise-based physical therapy in people with knee osteoarthritis through the use of wearable sensors.
- Trial name
- WESENS-OA (NCT04243096)
- Testing
- Exercise-based Physical Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston University Charles River Campus
Child Growth
Home-based Growth Charts in Indonesia
The investigators developed a home-based growth chart that offers a simple and inexpensive way for caregivers to have access to simple health and nutrition information guided by behavioural economics analysis as well as to track…
- Trial name
- NCT04222998
- Testing
- Home-based growth charts, Home visits for baseline surveys, Home visits for end line surveys
- Where
- Indonesia
- Volunteers
- 1,487 people
- Sponsor
- Boston University
Reading Disability, Anxiety
Evidence-Based Interventions to Enhance Outcomes Among Struggling Readers
Despite decades of research on reading disabilities, little is known about improving reading in the middle grades (i.e., grades 3-6) and advancements have been hindered by the narrow focus on reading problems alone without…
- Trial name
- NCT04059939
- Testing
- Reading, Anxiety Management, Classroom Business as Usual
- Where
- United States
- Volunteers
- 542 people
- Sponsor
- Boston University Charles River Campus
Stroke
Robotic Exosuit Augmented Locomotion (REAL) in the Clinic and Community
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL-m (NCT05315310)
- Testing
- Soft Exosuit
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston University Charles River Campus
Anemia, Anemia, Iron Deficiency
Iron Deficiency Anemia and Non-iron Deficiency Anemia in Pregnancy in India
This is a sub-study nested into the existing NICHD Global Network for Women's \& Children's Health Research Maternal Newborn Health (MNH) registry that is a prospective, observational population-based registry in Eastern…
- Conditions
- Anemia, Anemia, Iron Deficiency, Anemia of Pregnancy
- Trial name
- IDA & NIDA (NCT04708665)
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Schizophrenia, Schizoaffective Disorder
Comparing Thinking Skills for Work (TSW)Home Practice Program With Traditional TSW Program
The purpose of this study is to determine if using a tablet computer, which is a very small, easy-to-carry computer, to practice thinking exercises at home will help improve your attention, memory, and problem solving abilities.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
- Trial name
- NCT03005574
- Testing
- TSW-HP, TSW-T
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Boston University Charles River Campus
Vaping, Smoking Cessation
Vaping Prevention and Vaping in Youth (Vapechat)
Many youth are addicted to nicotine due to increased nicotine vaping (e.g., e-cigarettes). Unfortunately, there are no effective interventions to help teens quit vaping.
- Trial name
- Vapechat (NCT06003439)
- Testing
- Virtual Reality Program, VR Program
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Boston University
Lead Poisoning
RECLEAN Pilot Study
This is an exposure assessment pilot study tailored for families of construction workers living with a child. The investigators will compare home dust metal levels and resident's blood metal levels before and after an educational…
- Trial name
- RECLEAN (NCT04498845)
- Testing
- In-home assessment plan, Family educational session, Worker take home prevention training
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston University
Parkinson Disease
Responders to Rhythmic Auditory Cueing in Parkinson Disease
Parkinson disease (PD) is the second most common neurodegenerative disease affecting approximately 10 million people worldwide. It is a complex movement disorder that results in reduced walking ability.
- Trial name
- NCT05733819
- Testing
- Subject-specific optimized RAS, Active Walking
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston University Charles River Campus
Alcohol Drinking and Chronic Pain Intervention, Control Condition
Internet-based Video-conferencing to Address Alcohol Use and Pain: a Pilot Trial
This pilot study seeks to provide effect size estimates and test feasibility of a novel, integrated behavioral approach to reduce heavy drinking and chronic pain among patients in HIV-care delivered via internet-based…
- Trial name
- NCT04441593
- Testing
- Motivational and Cognitive-Behavioral Management for Alcohol and Pain (MCBMAP), Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Boston University Charles River Campus