Clinical trials: sponsored by British Columbia Cancer Agency
Neuropathic Pain Secondary to Radiation Therapy
Neuropathic Pain Caused by Radiation Therapy
To investigate if topical amitriptyline 2%, ketamine 1%, and lidocaine 5% in pluronic lecitine organogel (AKL in PLO gel) can improve management of neuropathic pain from radiation skin reactions adjunctively or better than…
- Trial name
- NP (NCT00798083)
- Testing
- topical amitriptyline 2%, ketamine 1%, and lidocaine 5% in pluronic lecitine organogel(AKL in PLO gel)
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- British Columbia Cancer Agency
Advanced Colorectal Cancer
Chemoradiation for Locally Advanced and Low Rectal Cancers: Avastin-Capecitabine-Oxaliplatin-Radiation REctal Cancer Trial
This phase II study will evaluate the effect of bevacizumab, capecitabine and oxaliplatin with radiation on rectal cancer. Researchers will also evaluate the tolerability (how it makes the patient feel) and safety of this…
- Trial name
- NCT00386828
- Testing
- Bevacizumab:
- Where
- 6 sites in Canada
- Volunteers
- 43 people
- Sponsor
- British Columbia Cancer Agency
Hormone Refractory Prostate Cancer
Study of Patupilone in Prostate Cancer Patients Who Progress After Hormone Therapy and Docetaxel Chemotherapy
The purpose of this study is to determine the efficacy of patupilone chemotherapy and to find out what effects (good and bad) the drug Patupilone has on patients with prostate cancer that has progressed following hormone…
- Trial name
- NCT00407251
- Testing
- Patupilone
- Where
- 5 sites in Canada
- Volunteers
- 73 people
- Sponsor
- British Columbia Cancer Agency
Neoplasms, Palliative Care
Acupuncture in Palliative Cancer Care
Research question: Can acupuncture improve symptom control and quality of life (QOL) in patients with advanced incurable cancer? The purposes of this study is to investigate the feasibility of performing a randomized trial with…
- Trial name
- NCT00302185
- Testing
- Acupuncture, Nurse-led supportive care
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- British Columbia Cancer Agency
Adenocarcinoma of the Prostate
A Study of BAY 43-9006 in Combination With Bicalutamide in Patients With Chemo-Naïve Hormone Refractory Prostate Cancer
Purpose: To determine the efficacy of BAY 43-9006 in combination with bicalutamide in patients with chemo-naïve hormone-refractory prostate cancer.
- Trial name
- NCT00430235
- Testing
- BAY 43-9006
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- British Columbia Cancer Agency
Breast Cancer
A Trial Testing Professional and Peer-led Support Online Support Groups for Young Canadian Breast Cancer Survivors
Young women who have finished treatment for breast cancer regularly report a lack of psychological and social support in their lives.
- Trial name
- CBCRA09 (NCT01089699)
- Testing
- online support group, home study support materials
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Lung Cancer, Precancerous Condition
Inositol in Preventing Lung Cancer in Patients With Bronchial Epithelial Dysplasia Who Are Current or Former Smokers
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Inositol may be effective in preventing the development of lung cancer in patients with bronchial…
- Trial name
- NCT00061997
- Testing
- inositol
- Where
- Canada
- Sponsor
- British Columbia Cancer Agency
Cervical Cancer, Precancerous Condition
Spectroscopy in Diagnosing Dysplasia and Neoplasia in the Cervix in Women Undergoing Colposcopy
RATIONALE: New diagnostic procedures, such as spectroscopy, may be a less invasive way to check for dysplasia and neoplasia in the cervix.
- Trial name
- NCT00632190
- Testing
- fluorophotometry, colposcopic biopsy, colposcopy
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Relapsed or Cisplatin-Refractory Germ Cell Cancer
Phase-II Study of SU011248 (Sunitinib)in Male Patients With Relapsed or Cisplatin-Refractory Germ Cell Cancer
The purpose of this study is to investigate the activity of SU011248 in subjects with cisplatin-refractory or multiply relapsed germ cell cancer. It is believed that SU011248 treatment may prove to increase disease response.
- Trial name
- NCT00371553
- Testing
- SU011248 (Sunitinib)
- Where
- 6 sites in Canada
- Volunteers
- 33 people
- Sponsor
- British Columbia Cancer Agency
Lymphoma
Oblimersen, Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma
RATIONALE: Monoclonal antibodies, such as rituximab, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells.
- Trial name
- NCT00070083
- Testing
- oblimersen sodium, rituximab, cyclophosphamide
- Where
- 4 sites in United States, Canada
- Sponsor
- British Columbia Cancer Agency
Lung Cancer
Budesonide in Treating Former and Current Smokers With Bronchial Dysplasia
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of budesonide may be an effective way to prevent bronchial dysplasia.
- Trial name
- NCT00005880
- Testing
- budesonide
- Where
- Canada
- Sponsor
- British Columbia Cancer Agency
Breast Neoplasms
The Use of Silver Leaf Dressing in the Prevention of Radiotherapy Induced Skin Reactions
The hypothesis is that silver leaf nylon dressing reduces the percentage of patients developing brisk erythema and moist desquamation while undergoing whole breast radiotherapy.
- Trial name
- NCT00207324
- Testing
- Silver Leaf Dressing
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- British Columbia Cancer Agency