Clinical trials: sponsored by Case Comprehensive Cancer Center
Laparotomy, Gynecologic Diseases
Enhanced Recovery After Surgery: A RCT of Perioperative Management of Gynecologic Patients
This is a single-blinded randomized control trial comparing the current perioperative care of the investigators gynecologic oncology patients with a standardized perioperative "enhanced recovery" pathway.
- Trial name
- NCT02357251
- Testing
- Enhanced recovery protocol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Case Comprehensive Cancer Center
Post-transplant Lymphoproliferative Disorder, PTLD
Single Agent Obinutuzumab in Relapsed/Refractory Post-Transplant Lymphoproliferative Disorder (PTLD)
Patients with post transplant lymphoproliferative disorder (PTLD) that have been treated with at least one type of chemotherapy, but whose lymphoma is not responding or coming back after the previous treatment will be asked to…
- Trial name
- NCT03086395
- Testing
- Obinutuzumab
- Sponsor
- Case Comprehensive Cancer Center
Multiple Myeloma
Psychoeducational and Behavioral Strategies in Reducing Distress and Anxiety in Patients With Multiple Myeloma and Their Family Caregivers
This pilot clinical trial studies how well psychoeducational and behavioral strategies work in reducing distress and anxiety in patients with multiple myeloma and their family caregivers.
- Trial name
- NCT02129569
- Testing
- Psychoeducational intervention, behavioral intervention, counseling intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Refractory Multiple Myeloma, Stage I Multiple Myeloma
Lenalidomide After Donor Stem Cell Transplant and Bortezomib in Treating Patients With High Risk Multiple Myeloma
This phase I trial studies the side effects and best dose of lenalidomide after donor stem cell transplant and bortezomib in treating patients with high-risk multiple myeloma.
- Conditions
- Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
- Trial name
- NCT01954784
- Testing
- fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Case Comprehensive Cancer Center
Stage I Non-Small Cell Lung Cancer, Stage II Non-Small Cell Lung Cancer
Feasibility Study of SBRT Plus Chemotherapy for Non-Small Cell Lung Carcinoma
This pilot clinical trial studies stereotactic body radiation therapy followed by combination chemotherapy in treating patients with non-small cell lung cancer.
- Trial name
- NCT02319889
- Testing
- Stereotactic Body Radiotherapy, Carboplatin, Paclitaxel Albumin-Stabilized Nanoparticle Formulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer
Evaluating the Effectiveness of Art Therapy on Mood, Anxiety, and Pain Levels in Cancer Patients
Participants in this research study are asked to tell about their experience with art therapy. Participants in this research study are currently receiving chemotherapy treatment for cancer.
- Trial name
- NCT02659345
- Testing
- Emotions Thermometer, Art Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Case Comprehensive Cancer Center
Non Small Cell Lung Cancer, Advanced Triple Negative Breast Cancer
A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients
This study will look at the safety of the combination of three drugs (CDX-1401, Poly-ICL, and Pembrolizumab) and its effect on decreasing tumors. Pembrolizumab is an experimental cancer drug.
- Conditions
- Non Small Cell Lung Cancer, Advanced Triple Negative Breast Cancer, Small Cell Lung Cancer, Urothelial Cancer
- Trial name
- NCT02661100
- Testing
- Pembrolizumab, CDX-1401, Poly-ICLC
- Sponsor
- Case Comprehensive Cancer Center
Recurrent Bladder Cancer, Stage 0 Bladder Cancer
Urinary Diversion During Robotic Assisted Radical Cystectomy in Patients With Bladder Cancer
This randomized clinical trial studies intracorporeal or extracorporeal urinary diversion during robotic assisted radical cystectomy in reducing complications in patients with bladder cancer.
- Conditions
- Recurrent Bladder Cancer, Stage 0 Bladder Cancer, Stage I Bladder Cancer, Stage II Bladder Cancer
- Trial name
- NCT02252393
- Testing
- robot-assisted laparoscopic surgery, intraoperative complication management/prevention, quality-of-life assessment
- Sponsor
- Case Comprehensive Cancer Center
Kidney/Urinary Cancer
Optical Coherence Tomography in Staging Patients With Upper Tract Urothelial Cancer
This clinical trial studies how well optical coherence tomography works in staging patients with upper-tract urothelial carcinomas.
- Trial name
- NCT02108587
- Testing
- optical coherence tomography
- Sponsor
- Case Comprehensive Cancer Center
Melanoma (Skin)
Study of Tumor Tissue Samples From Patients With Stage I, Stage II, or Stage III Malignant Melanoma
RATIONALE: Studying the genes expressed in samples of tumor tissue from patients with cancer may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00991991
- Testing
- gene expression analysis, polymerase chain reaction, polymorphism analysis
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center
Lung Cancer
Topotecan in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as topotecan, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00087048
- Testing
- topotecan hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Case Comprehensive Cancer Center
Ciliary Body and Choroid Melanoma, Medium/Large Size, Ciliary Body and Choroid Melanoma, Small Size
Radioembolization and Ipilimumab in Treating Patients With Uveal Melanoma With Liver Metastases
This pilot clinical trial studies radioembolization and ipilimumab in treating patients with uveal melanoma with liver metastases.
- Conditions
- Ciliary Body and Choroid Melanoma, Medium/Large Size, Ciliary Body and Choroid Melanoma, Small Size, Extraocular Extension Melanoma, Iris Melanoma
- Trial name
- NCT01730157
- Testing
- ipilimumab, yttrium Y 90 glass microspheres, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Case Comprehensive Cancer Center
Short Segment Barrett's Esophagus, Long Segment Barrett's Esophagus
Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus
This study is being conducted to determine if vitamin D supplementation increases the level of a protein that may be involved in decreasing the risk of esophageal cancer in patients with Barrett's esophagus.
- Trial name
- NCT01465113
- Testing
- Omeprazole, Vitamin D3, upper endoscopy
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- Case Comprehensive Cancer Center
Precancerous Condition, Prostate Cancer
Study of Blood Samples From Older Patients at High Risk of Developing Prostate Cancer and From Healthy Male Participants
RATIONALE: Studying samples of blood in the laboratory from patients who are at high risk of developing prostate cancer may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00898274
- Testing
- immunoenzyme technique, laboratory biomarker analysis
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma
A Pilot Study of SBRT With Adjuvant Pazopanib for Renal Cell Cancer
This pilot clinical trial studies the side effects of stereotactic body radiation therapy and pazopanib hydrochloride in treating patients with kidney cancer who are not able to undergo surgery.
- Trial name
- NCT02307474
- Testing
- Stereotactic Radiosurgery, Pazopanib Hydrochloride
- Where
- 2 sites in United States
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Prospective Chart-Review: Impact of Combination - Digital Breast Tomosynthesis + Digital Mammography
Digital Breast Tomosynthesis (DBT) is a technology that has been developed to improve lesion detection in dense breasted women. Even though DBT has been regarded as a study for dense breasted women, it may also improve lesion…
- Trial name
- NCT01593384
- Volunteers
- healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Compliance to a Hormone Therapy Regimen in Breast Cancer
RATIONALE: Understanding how well patients comply with their treatment regimen may help doctors plan the best treatment and ongoing care.
- Trial name
- NCT00666822
- Testing
- compliance monitoring, medical chart review, questionnaire administration
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Case Comprehensive Cancer Center
Stage I Prostate Cancer, Stage IIA Prostate Cancer
Robotic Athermal Nerve-Sparing Radical Prostatectomy
This randomized clinical trial compares a recently developed technique, called robotic laparoendoscopic single-site radical prostatectomy (R-LESS RP), to the current standard of robotic technique for prostate cancer…
- Trial name
- NCT02079155
- Testing
- robot-assisted laparoscopic surgery, laboratory biomarker analysis, quality-of-life assessment
- Sponsor
- Case Comprehensive Cancer Center
Esophageal Cancer
Gefitinib in Treating Patients With Recurrent or Metastatic Esophageal or Gastroesophageal Junction Cancer
RATIONALE: Gefitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well gefitinib works in treating patients with recurrent or metastatic…
- Trial name
- NCT00268346
- Testing
- ZD1839
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Case Comprehensive Cancer Center
Skin Carcinoma, Skin Melanoma
Improving Sun-Protective Behaviors and Skin Self-Examinations Among African Americans
This randomized clinical trial uses an educational brochure and online tutorial program to assess sun-protective behavior and skin self-examination among African Americans.
- Trial name
- NCT02417948
- Testing
- Written Educational Brochure, Online educational video
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center