Clinical trials: completed, sponsored by Case Comprehensive Cancer Center
Actinic Keratoses
Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses
The purpose of the study is to test a new video device for actinic keratoses. The device takes images of your skin lesions during the treatment, to learn whether this device can predict how well the treatment is working.
- Trial name
- NCT05923060
- Testing
- Topical Aminolevulinate, Photodynamic therapy (PDT), Red light illumination
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Case Comprehensive Cancer Center
Lung Cancer, Left Sided Breast Cancer
A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose
Data collection and assessment on patients with left-sided breast cancer or undergoing lung stereotactic body radiation therapy (SBRT) utilizing continuous positive airway pressure (CPAP) devices.
- Trial name
- NCT05142358
- Testing
- Continuous Positive Airway Pressure, Deep inspiratory breath hold, Free Breath
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Case Comprehensive Cancer Center
Leukemia
Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation
In the United States, thiotepa has been utilized in reduced intensity conditioning regimens for alternative donor courses (double umbilical cord blood transplant (dUCBT) and haplo-identical transplants).
- Trial name
- NCT03342196
- Testing
- Melphalan, Thiotepa, Fludarabine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Prostate Cancer
NAVAH Impact on Radiation Therapy Completion in Black Breast & Prostate Cancer Patients
African-Americans have disparately limited access to optimal cancer care. They have the highest overall cancer death rate and shortest survival time of any racial or ethnic group in the United States.
- Trial name
- NCT05978232
- Testing
- NAVAH
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer Pain, Oncology Pain
Reiki Therapy to Improve Key Symptoms in Integrative Oncology Clinic (REIKI)
The purpose of this research is to investigate the delivery of Reiki to integrative oncology patients and assess its potential for improving cancer-related symptoms in this population.
- Trial name
- NCT06354049
- Testing
- Reiki
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Case Comprehensive Cancer Center
Basal Cell Carcinoma of the Head and Neck
Neoadjuvant-Adjuvant Pembrolizumab in Resectable Advanced Basal Cell Carcinoma of H&N
The purpose of this study is to evaluate anti-PD-1 Neoadjuvant therapy in Basal cell carcinoma to provide a better outcome when administered prior to surgery and provide a therapeutic strategy to avoid surgery altogether.
- Trial name
- NCT04323202
- Testing
- Pembrolizumab, Tissue collection
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
Actinic Keratosis
Short Contact Protocols to Reduce Pain During 10% ALA Gel Red-light Photodynamic Therapy of Actinic Keratoses
The goal of this clinical trial is to see if shorter Photodynamic Therapy (PDT) treatment times will still be effective at treating actinic keratoses (AK) while reducing or eliminating the pain that patients sometimes experience…
- Trial name
- NCT06027619
- Testing
- Topical aminolevulinate (10% ALA gel), Red light illumination
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program
More than 65% of breast cancer survivors are overweight and less than one-third participate in recommended levels of physical exercise.
- Trial name
- NCT04365569
- Testing
- Nutrition and physical activity counseling program
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Case Comprehensive Cancer Center
Thrombocytopenia
Collection of Peripheral Blood From Patients With Hematologic Malignancies With Thrombocytopenia
The purpose of the research project is to collect one blood sample from participants who are affected by very low platelets as a result of their condition or their treatment.
- Trial name
- NCT06824727
- Testing
- Baseline cell blood counts
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Case Comprehensive Cancer Center
Multiple Myeloma
Effects of Early Palliative Care Integration on Patients With Newly Diagnosed Multiple Myeloma
Multiple Myeloma (MM) is a common type of cancer involving the cells in the blood (commonly affecting bones, kidneys and blood).
- Trial name
- NCT04248244
- Testing
- Palliative Care, FACT-MM questionnaire, HADS questionnaire
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center
Stem Cell Transplant Complications, Myeloma
Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT
As the average age of individuals undergoing stem cell transplant continues to increase, challenges associated with balancing the side effects of cancer treatments while also managing other medical conditions develop.
- Conditions
- Stem Cell Transplant Complications, Myeloma, Lymphoma, Allogeneic and Autologous Stem Cell Transplant
- Trial name
- NCT04194840
- Testing
- physical therapy consult, Cognitive Assessment, Cancer Aging Research Group (CARG) assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center
Percutaneous Tumor Ablation
Intra-procedural 360-degree Display for Performing Percutaneous Liver Tumor Ablation
Medical images used to guide treatment of tumor(s) are presently displayed on flat-panel monitors (like screens used with computers).
- Trial name
- NCT03500757
- Testing
- HoloLens
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Case Comprehensive Cancer Center
Positive FIT or Stool DNA Testing Follow up
Incomplete Follow Up After Positive FIT or Stool DNA Testing: A Multimethod Approach
This study seeks to determine whether a patient navigator can help improve follow up care after a stool test shows the presence of blood or other abnormal markers.
- Trial name
- NCT03817905
- Testing
- Patient navigator
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center
Recurrent Glioblastoma
Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma
The purpose of this study is to determine the safety and tolerability of Regorafenib in patients with recurrent or progressive glioblastoma (GBM) who have progressed on bevacizumab.
- Trial name
- NCT04051606
- Testing
- Regorafenib
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Case Comprehensive Cancer Center
Keratinocyte Carcinoma
Teach-back Method on Patient Satisfaction and Adherence to Wound Care Regimen
The purpose of this study is to examine a different way to educate patients about taking care of their wound and see how this method affects patient satisfaction, compliance to the wound care regimen, and patient experience.
- Trial name
- NCT04377971
- Testing
- SOC education, Ask-tell-ask education, Participant satisfaction survey
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer Prevention
Getting Ahead for Cancer Control
A new, practical program, entitled Getting Ahead in a Just-Gettin'-By World, provides a novel approach to addressing this previously intractable problem.
- Trial name
- NCT03247634
- Testing
- Getting Ahead in a Just-Gettin'-By World
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Adult Giant Cell Glioblastoma, Adult Glioblastoma
NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma
NovoTTF-100A is a device and Bevacizumab is a study drug that have both been approved by the FDA (Food and Drug Administration) for use as monotherapy in treating glioblastoma multiforme.
- Conditions
- Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma, Recurrent Adult Brain Tumor
- Trial name
- NCT01894061
- Testing
- Bevacizumab, NovoTTF-l00A, Quality of Life Assessment
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Case Comprehensive Cancer Center
Metastatic or Unresectable Melanoma
Nivolumab in Combination With Talazoparib in Melanoma and Mutations in BRCA or BRCA-ness Genes
The purpose of this study is to evaluate how effective the study drugs, nivolumab (also known as Opdivo®) and talazoparib (also known as Talzenna®) are when given as a combination treatment for unresectable or metastatic…
- Trial name
- NCT04187833
- Testing
- Nivolumab, Talazoparib
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Assessing the Benefit of Art & Music Therapy on Quality of Life in Patients With Breast Cancer
This is a study of art-based and music-based therapy programs lasting three months (with additional follow-up 3 months after the end of the trial) in breast cancer patients currently receiving therapy as well as in cancer…
- Trial name
- NCT04493034
- Testing
- Art Therapy, Music Therapy
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Case Comprehensive Cancer Center
Basal Cell Carcinoma, Basal Cell Nevus Syndrome
Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma
The purpose of this study is to study 50 patients with multiple Basal Cell Carcinoma (BCC) who will be receiving Photodynamic Therapy (PDT) as treatment for their tumors.
- Trial name
- NCT03467789
- Testing
- Dietary Vitamin D3 pre-treatment, Photodynamic therapy, Serum Maintenance Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Case Comprehensive Cancer Center