Clinical trials: sponsored by Centre for Addiction and Mental Health
Risky Alcohol Consumption
Web-based Personalized Feedback for University Students
Excessive alcohol consumption in university students continues for be a serious public health concern with a variety of negative consequences.
- Trial name
- NCT01521078
- Testing
- Check Your Drinking University version
- Where
- Canada
- Volunteers
- 425 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder
Transcranial Direct Current Stimulation (tDCS) in the Treatment of Major Depressive Disorder (MDD)
The project will investigate the use of a novel neuromodulatory technique, transcranial direct current stimulation (tDCS) in the treatment of patients with major depressive disorder.
- Trial name
- NCT01078948
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder
Treating Refractory Major Depressive Disorder With Repetitive Transcranial Magnetic Stimulation
Studies exploring the efficacy of repetitive transcranial magnetic stimulation (rTMS) as a treatment for refractory major depressive disorder (MDD) have shown significant promise.
- Trial name
- NCT00305045
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- Centre for Addiction and Mental Health
Refractory Schizophrenia
Repetitive Transcranial Magnetic Stimulation for Refractory Auditory Hallucinations in Schizophrenia
Studies using repetitive transcranial magnetic stimulation (rTMS) as a treatment for refractory auditory hallucinations (AH) in schizophrenia have shown promise.
- Trial name
- NCT01386918
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depression
Attachment Security as Mediator and Moderator of Outcome in Major Depression
In this study, the focus is on an individual's attachment security and its relation to treatment outcome in Major Depression.Adult attachment reflects how one seeks psychological and physical proximity to others for security and…
- Trial name
- NCT00461279
- Testing
- Cognitive Behavior Therapy, Interpersonal Psychotherapy
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Centre for Addiction and Mental Health
Anxiety, Depression
The Feelings Club: Evaluating a School-based Intervention for Children at Risk for Depression and Anxiety Disorders
Anxiety and mood disorders are among the most prevalent mental health problems in childhood. They have severe long-term morbidity, and associated academic and social impairment.
- Trial name
- NCT00164203
- Testing
- Cognitive Behavioral Therapy, School-based CBT, activity control condition
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder, Dysthymic Disorder
Cognitive Behavioral Therapy for Early-Onset Depression
Depression is a debilitating illness affecting large numbers of young people. In this study, children and adolescents ages 10 to 17 meeting criteria for clinical depression will participate in a 15-session group therapy…
- Trial name
- NCT00096642
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Problem Gambling
A Personalized Feedback Intervention for Problem Gamblers
The main aim of this randomized controlled trial is to evaluate the sustained efficacy of a personalized feedback intervention for problem gamblers.
- Trial name
- NCT00578357
- Testing
- personalized feedback intervention
- Where
- Canada
- Volunteers
- 209 people
- Sponsor
- Centre for Addiction and Mental Health
Nicotine Dependence
Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar Disorder
Bipolar Disorder is a chronic relapsing mental disorder characterized by periods of elevated, expansive and irritable mood, often alternating with periods of significant clinical depression.
- Trial name
- NCT01093937
- Testing
- varenicline
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Alcohol Dependence
Helping Problem Drinkers on the Internet
The main aim of this study is to compare the impact of a minimal and a full Internet-based self-help intervention for problem drinkers in the general population.
- Trial name
- NCT01114919
- Testing
- Check Your Drinking (CYD), Alcohol Help Centre (AHC)
- Where
- Canada
- Volunteers
- 246 people
- Sponsor
- Centre for Addiction and Mental Health
Alcoholism
An Internet-based Intervention for Problem Drinking
The main aim of this randomized controlled trial is to evaluate the efficacy of an Internet-delivered self-help intervention for problem drinkers in the general population.
- Trial name
- NCT00367575
- Testing
- Internet personalized alcohol feedback (PAF)
- Where
- 3 sites in United States, Canada
- Volunteers
- 359 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia
Antipsychotic Polypharmacy in Schizophrenia
The literature suggests that when a patient is prescribed more than one antipsychotic for at least 30 days, he or she is likely to continue on that combination.
- Trial name
- NCT00493233
- Testing
- 2 antipsychotic medications (combinations of olanzapine, risperidone, clozapine, seroquel, haldol, perphenazine)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre for Addiction and Mental Health
Substance Abuse, Drug Addiction
Integrating Mindfulness-Based Skills Training Into Brief Outpatient Treatment for Substance Abusing Youth
The proposed study will evaluate the clinical effectiveness of integrating mindfulness-based skills training into a standardized brief group intervention for youth (ages 16 to 24) identified as having problematic substance use.
- Trial name
- NCT00244699
- Testing
- MI Alone or Plus Mindfulness-Based Skills Training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Smoking, Nicotine Dependence
Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia
Cigarette smoking decreases life expectancy, causes devastating health complications, and costs society billions of dollars each year.
- Conditions
- Smoking, Nicotine Dependence, Schizophrenia, Schizophreniform Disorders
- Trial name
- NCT00407277
- Testing
- Nicotine patch, smoking cessation group therapy
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Hypersalivation
Treatment of Clozapine-Induced Hypersalivation Ipratropium Bromide
Hypersalivation (Too much saliva) and drooling is a side effect experienced by 31% of people taking the antipsychotic clozapine.
- Trial name
- NCT00381589
- Testing
- ipratropium bromide 0.03% spray
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Centre for Addiction and Mental Health
Depression, Major Depressive Disorder
Stress Generation and Recurrent Depression: The Role of Differential Treatment Response
Depression affects over one million people in Canada, resulting in $14.4 billion per year in costs to Canadian society. In order to prevent this often lifelong disorder, it is critically important to identify risk factors for the…
- Trial name
- NCT00745017
- Testing
- Cognitive Behavioral Therapy, Interpersonal Therapy, Antidepressant medication
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Centre for Addiction and Mental Health
Depression, Major Depressive Disorder
Patient Dimensions as Predictors of Varied Treatment Responses and Outcomes in Patients With Major Depression
Depression affects over one million people in Canada, resulting in $14.4 billion per year in costs to Canadian society. In order to prevent this often lifelong disorder, it is critically important to identify risk factors for the…
- Trial name
- NCT00744406
- Testing
- Cognitive Behavioral Therapy, Interpersonal Therapy, Antidepressant medication (sertraline ,paroxetineor or venlafaxine)
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Centre for Addiction and Mental Health
Gambling
Development and Validation of a Mindfulness Intervention for Problem Gambling: An Exploratory Study
In recent years, mindfulness meditation has been shown to be a promising approach for alleviating emotional distress associated with chronic medical and psychiatric conditions and in reducing relapse following treatment for…
- Trial name
- NCT00495261
- Testing
- Mindfulness-enhanced cognitive behavioural therapy (MCBT), relaxation-enhanced cognitive behavioural therapy (RCBT)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre for Addiction and Mental Health
Concurrent Alcohol Dependence and Pathological Gambling
Naltrexone in the Treatment of Concurrent Alcohol Dependence and Pathological Gambling
This study assessed whether naltrexone, an opioid antagonist, might be effective in reducing excessive gambling behavior in people who also drink heavily.
- Trial name
- NCT00326807
- Testing
- Naltrexone
- Where
- 2 sites in Canada, Finland
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health