Clinical trials: sponsored by Changhai Hospital
Pancreatitis, Chronic, Exocrine Pancreatic Insufficiency
Endotherapy for Painless Chronic Pancreatitis
This is a prospective randomized controlled trial. . Patients will be divided into conservative or endoscopic group and fecal pancreatic elastase-1 (FE-1) is tested to evaluate pancreatic exocrine function.
- Conditions
- Pancreatitis, Chronic, Exocrine Pancreatic Insufficiency, Abdominal Pain, Cholangiopancreatography, Endoscopic Retrograde
- Trial name
- EACH (NCT05261997)
- Testing
- extracorporeal shock wave lithotripsy and endoscopic drainage of the main pancreatic duct, pancreatic enzyme(Pancreatin Enteric-coated Capsules or Oryz-Aspergillus Enzyme and Pancreatin Table), antidiabetic medicine(Acarbose Tablets, Glucophage, Glimepirde Tablets)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital
Gastric Disease, Capsule Endoscopy
Pronase Granules in Gastric Cleaning
Magnetically controlled capsule endoscopy (MCE) is now widely used all over the world. However, the standard gastric preparation method by dimethicone we used clinically still has mucus at the bottom of the stomach.
- Trial name
- NCT05249933
- Testing
- Deyou; Beijing Tide Pharmaceutical Co, China, containing 20,000 iu pronase granules combined with 1 g NaHCO3 to maintain the intragastric PH at 6-8
- Where
- China
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Disease of Lower Digestive Tract, Nurse-Patient Relations
Design and Clinical Application of Colonoscopy Position Identification Sheet
Before colonoscopy, the nursing staff need to educate the patient with posture coordination.However, it is difficult for some patients to understand the placement of the correct body position, which takes too much time to conduct…
- Trial name
- NCT05239481
- Testing
- colonoscopy position identification sheet, Traditional disposable cleaning sheet
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases
Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis
Accumulating evidence indicates that patient- derived organoids (PDOs) can predict drug responses in the clinic. Metastasis is the main cause of death in colorectal cancer patients, and the treatment of patients with liver…
- Trial name
- NCT05183425
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital
Colon Polyp, Colorectal Adenoma
9 Minutes for Tandem Colonoscopy Withdrawal
A mean withdrawal time of at least 6 minutes has been considered to be one of the critical quality criterions of colonoscopy. Recently, our group completed a multicenter randomized controlled trial, which proved that prolonging…
- Trial name
- NCT04797065
- Testing
- 6-minute then 9-minute withdrawal, 9-minute then 6-minute withdrawal
- Where
- China
- Volunteers
- 733 people
- Sponsor
- Changhai Hospital
Digestive System Disease, Diagnoses Disease
A Novel Portable Upper Gastrointestinal Endoscopy System
The application of conventional endoscopy in remote and outdoor areas lacking facilities remains challenges. Thus, the investigators developed a novel portable upper gastrointestinal endoscopy system that has the same functions…
- Trial name
- NCT05211258
- Testing
- a novel portable upper gastrointestinal endoscopy system
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Tricuspid Valve Regurgitation
THE TRAVEL II TRIAL: Transcatheter Right Atrial-ventricular Valve rEplacement With LuX-Valve Via Jugular Vein
The trial aims to evaluate the safety and effectiveness of LuX-Valve transcatheter tricuspid valve and delivery system via jugular vein which are intended to use in symptomatic patients with severe tricuspid regurgitation and…
- Trial name
- NCT05194423
- Testing
- Tricuspid Valve Replacement System via jugular vein
- Where
- 9 sites in China
- Volunteers
- 150 people
- Sponsor
- Changhai Hospital
Colon Polyp, Colorectal Adenoma
a Low-residue Diet for Bowel Preparation
Previous researches demonstrated that a prepackaged low-residue diet (LRD) could achieve better bowel preparation quality compared with a self-prepared LRD.
- Trial name
- NCT03943758
- Testing
- Prepackaged Low-residue diet, Self-prepared Low-residue diet
- Where
- China
- Volunteers
- 589 people
- Sponsor
- Changhai Hospital
Coronary Arteriosclerosis
Association Between Carotid Plaque Length and Cardiovascular Events
This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No.
- Trial name
- NCT05159804
- Where
- 5 sites in China
- Volunteers
- 3,637 people
- Sponsor
- Changhai Hospital
Gastrointestinal Disease, Infectious Disease
Feasibility of Non-contact Magnetically-controlled Capsule Endoscopy During COVID-19 Pandemic
In December 2019, an outbreak of pneumonia associated with a novel coronavirus named as severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) was reported in Wuhan city, China, and spread exponentially throughout China and…
- Conditions
- Gastrointestinal Disease, Infectious Disease, Capsule Endoscopy
- Trial name
- NCT04389333
- Testing
- non-contact magnetically-controlled capsule endoscopy
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Polyp
National Colorectal Polyp Care
This study has three main purposes：screening: the first purpose is to evaluate the diagnostic value of combintion of the life risk factors and immunochemical fecal occult blood test (FIT) on detection of colorectal neoplasia in…
- Trial name
- NCPC (NCT03712059)
- Testing
- FIT test and colonoscopy, Polypectomy and biopsy, Classification
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis, Genetic Mutation
An Observational Study on the Natural Course of Chronic Pancreatitis
To explore the impact on genetic and environmental factors for clinical manifestation, and the progression of chronic pancreatitis, including development of pancreatic insufficiency and other complications.
- Conditions
- Chronic Pancreatitis, Genetic Mutation, Smoking, Tobacco, Drinking, Alcohol
- Trial name
- NCT04574297
- Testing
- smoking and alcohol assumption, genetic sequencing
- Volunteers
- 798 people
- Sponsor
- Changhai Hospital
Stomach Diseases, Small Intestine Disease
Magnetically Controlled Capsule Endoscopy in Visualization of the UGI and Small Intestine
In this study, we retrospectively analyzed the videos of combined upper digestive tract and small intestine examination under MCE, so as to clarify the feasibility and diagnostic efficacy of MCE in one-time examination of the…
- Trial name
- NCT05069233
- Testing
- UGI+SB
- Where
- China
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Esophageal Diseases
Ultrasound Capsule Endoscopy for Esophagus Examination
The aim of this pilot study is to assess the feasibility and safety of the clinical application of ultrasound capsule endoscopy in esophageal examination compared with conventional endoscopic ultrasound examination.
- Trial name
- NCT05054933
- Testing
- ultrasound capsule endoscopy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Gastrointestinal Disease
Feasibility of Remote MCE for Upper GI Tract Examination Under Five-generation Network
With the combination of robotic and 5G network communication technology, telemedicine becomes more and more feasible and efficient.
- Trial name
- NCT04670692
- Testing
- 5G-MCE examination, MCE examination
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Urothelial Carcinoma
A Prospective, Multi-centre, Single-blinded Study of UroCAD for Urothelial Carcinoma Diagnosis and Follow-up
Urothelial carcinoma (UC) is common malignancy and is considered to be one of the costliest cancers. The traditional diagnostic methods of UC present with some shortcomings.
- Trial name
- NCT04432909
- Testing
- The level of CNV
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Changhai Hospital
Urothelial Carcinoma, Diagnoses Disease
UroCAD Assay Combined With Computed Tomography Urography and Urine Cytology for UTUC Diagnosis.
Upper tract urothelial carcinoma (UTUC) diagnosis include urography using computed tomography urography (CTU) or urography using MRI (MRU). The sensitivity of CTU decreases substan¬tially with decreasing lesion size.
- Conditions
- Urothelial Carcinoma, Diagnoses Disease, Ureter Cancer, IMAGE
- Trial name
- NCT05043662
- Testing
- UroCAD assay, CTU examination and urine cytology
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Changhai Hospital
Acute Ischemic Stroke
CAPTURE Registration Trial of the Thrombectomy System for the Treatment of Acute Ischemic Stroke.
As this will be a pre-market registration trial, in which devices will be used in accordance with appropriately labeled indications, pre-study notifications and approval requests will be addressed with CFDA.
- Trial name
- NCT04995757
- Testing
- Stent Retriever
- Where
- China
- Volunteers
- 239 people
- Sponsor
- Changhai Hospital
Pancreatic Space Occupying
Research on the Value of Genomics Research Based on Ultrasound Endoscopic Biopsy in the Differential Diagnosis and Prognostic Evaluation of Pancreatic Occupancy
To clarify the value of genomic testing in the clinical diagnosis or prognosis of pancreatic space occupation, provide a basis for the selection of clinical diagnosis methods for pancreatic space occupation, optimize clinical…
- Trial name
- NCT04986215
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Pancreatic Tumor
Phase ǀ Study on Pancreatic Cancer Treated by CyberKnife
The maximum tolerated dose on locally advanced unresectable pancreatic tumor treated with CyberKnife SBRT will be evaluated.
- Trial name
- NCT02716207
- Testing
- CyberKnife
- Where
- 2 sites in China
- Volunteers
- 16 people
- Sponsor
- Changhai Hospital