Clinical trials: sponsored by Changhai Hospital
Capsule Endoscopy
MCE Direct Visualization of Drug Behavior in Upper-gastrointestinal Tract
The investigators aim to explore the feasibility of MCE in direct, real-time visualization of drug behavior in upper-gastrointestinal tract, which presented by the adhesion, distribution, and dissipation characteristics of dyed…
- Trial name
- NCT04327869
- Testing
- Magnetically controlled capsule endoscopy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Cirrhosis, Liver, Upper Gastrointestinal Bleeding
Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding
The investigators studied the renal function index level in terlipressin treated cirrhotic patients with upper-gastrointestinal bleeding at different time point.
- Trial name
- NCT04358016
- Testing
- Terlipressin, Somatostatin
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Changhai Hospital
Gastrointestinal Disease, Infectious Disease
Non-contact Endoscopy at Covid-19 Outbreak
The COVID-19 outbreak and spread throughout the world now constitutes a global public health emergency. Direct contact between doctors and patients in daily practice bears potential risk of Covid-19 infection, and telemedicine…
- Trial name
- NCT04320953
- Testing
- Non-contact MCE system
- Where
- China
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colon Polyps, Colorectal Adenomas
9 Minutes for Colonoscopy Withdrawal
A withdrawal time of at least 6 minutes has been considered to be necessary to guarantee the adenoma detection rate and the critical quality criterion of colonoscopy.
- Trial name
- NCT03399045
- Testing
- 9-minute withdrawal, 6-minute withdrawal
- Where
- China
- Volunteers
- 1,027 people
- Sponsor
- Changhai Hospital
Capsule Endoscopy
Real-Time Identification System of Magnetically Controlled Capsule Endoscopy Using Artificial Intelligence
The aim of this study is to evaluate the performance of real-time auxiliary system based on artificial intelligence algorithm in lesion detection and quality control in magnetically controlled capsule endoscopy.
- Trial name
- NCT04203264
- Testing
- Real-time artificial intelligence identification system
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Liver Cirrhosis
Safety and Efficacy of SHED for Decompensated Liver Cirrhosis
This study is an prospective, randomized control study. Patients with decompensated cirrhosis will be randomly assigned to receive 4 times of SHED treatment plus standard medical care(treatment）or standard medical care (control).
- Trial name
- NCT03957655
- Testing
- SHED group
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changhai Hospital
Chronic Hepatitis b
IL-35+Breg/Il-35 Effect on T Cell Immune in Patients With CHB
The investigators observed the level of IL-35 secreting B regulatory (IL-35+Bregs) cells in peripheral blood cells in patients with chronic hepatitis B, and analysed the relationship between the IL-35+Bregs level and disease…
- Trial name
- NCT03734783
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Pancreatic Diseases
Diagnostic Efficacy of FFOCT Imaging for Tissue Sample Obtained by EUSFNB
In most Asian medical centers, rapid on-site cytology evaluation is not available, the number of needle passes of EUS-FNA is decided by endoscopists.
- Trial name
- NCT04153318
- Testing
- full-field optical coherence tomography
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital
Ischemic Stroke, Large Vessel Occlusion
Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals
Background: Intravenous thrombolysis (IVT) combined with mechanical thrombectomy (MT) has been proven safe and effective in patients with acute ischemic stroke (AIS) of anterior circulation large vessel occlusion (LVO).
- Conditions
- Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- DIRECT-MT (NCT03469206)
- Testing
- intra-arterial thrombectomy, Intravenous thrombolysis
- Where
- China
- Volunteers
- 656 people
- Sponsor
- Changhai Hospital
Pancreatic Mass
Comparing the Diagnostic Efficacy of Different Suction Techniques for EUS-FNB of Pancreatic Solid Lesions
There are many factors that can affect the diagnostic yield of EUS-FNA, including lesion factors, the endoscoist experience, the needle size, the number of needle passes, and the suction technique.
- Trial name
- NCT04100941
- Testing
- standard suction, slow pull, wet suction
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Outpatients
Detachable String Magnetically Controlled Capsule Endoscopy for Completely Viewing of Esophagus and Stomach
The purpose of the study is to determine the safety and feasibility of the new technique,detachable string magnetically controlled capsule endoscopy(DS-MCE)for evaluating gastric and esophagus diseases.
- Trial name
- NCT03457909
- Testing
- DS-MCE
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Chronic Pancreatitis, Idiopathic Chronic Pancreatitis
Classification and Comparison of Early-onset and Late-onset Idiopathic Chronic Pancreatitis
Classification of early-onset idiopathic chronic pancreatitis (EOICP) and late-onset idiopathic chronic pancreatitis (LOICP) was proposed based on bimodal distribution of age at onset of idiopathic chronic pancreatitis (ICP).
- Trial name
- NCT03953937
- Where
- China
- Volunteers
- 1,633 people
- Sponsor
- Changhai Hospital
Stricture Ureter
A Study of Balloon Dilatation for the Treatment of Benign Ureteral Stricture
This study is designed to treat benign ureteral stricture with balloon dilatation through prospective multicenter studies. It aims to indications, procedure standards, and therapeutic effects of balloon dilation, and provide…
- Trial name
- NCT04021901
- Testing
- balloon dilatation
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Changhai Hospital
Stomach Diseases
Repetitive Position Change Improves Gastric Cleanliness for MCE
By comparing dimethicone administration with/without subsequent repetitive position change before magnetically controlled capsule endoscopy (MCE) examination, the investigators aim to determine the efficacy of repetitive position…
- Trial name
- NCT03514966
- Testing
- Position change group
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Urothelial Carcinoma, Diagnoses Disease
Application of UCAD for Diagnosing Urothelial Carcinoma.
Chromosomal instability (CIN) refers to ongoing chromosome segregation errors throughout consecutive cell divisions. CIN is a hallmark of human cancer, and it is associated with poor prognosis, metastasis, and therapeutic…
- Conditions
- Urothelial Carcinoma, Diagnoses Disease, Chromosomal Abnormality, Urine Marking
- Trial name
- NCT03998371
- Testing
- Low-coverage whole-genome sequencing of urine exfoliated cells
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Bronchoscopy, Sedation
Sedation Strategies for Diagnostic Bronchoscopy 2
Diagnostic bronchoscopy is an invasive procedure performed to diagnose respiratory diseases. But pain has been complained by most of the patients receiving such procedures.
- Trial name
- NCT03983889
- Testing
- Midazolam, Fentanyl, Dexmedetomidine
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Bronchoscopy, Sedation
Sedation Strategies for Therapeutic Bronchoscopy 2
Therapeutic bronchoscopy is a common procedure to treat respiratory diseases. The procedure includes stent implantation, bronchus dilation, electronic incision, laser therapy, and so on.
- Trial name
- NCT03983915
- Testing
- Dexmedetomidine, Remifentanil, Laryngeal mask
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital
Bronchoscopy, Sedation
Sedation Strategies for Therapeutic Bronchoscopy
Therapeutic bronchoscopy is a common procedure to treat respiratory diseases. The procedure includes stent implantation, bronchus dilation, electronic incision, laser therapy, and so on.
- Trial name
- NCT03406546
- Testing
- Dexmedetomidine, Remifentanil, Laryngeal mask
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Changhai Hospital
Bronchoscopy, Sedation
Sedation Strategies for Diagnostic Bronchoscopy
Diagnostic bronchoscopy is an invasive procedure performed to diagnose respiratory diseases. But pain has been complained by most of the patients receiving such procedures.
- Trial name
- NCT03406533
- Testing
- Midazolam, Dexmedetomidine, Remifentanil
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Changhai Hospital
Pancreatic Cancer
EUS-guided Celiac Plexus Neurolysis for the Treatment of Abdominal Pain in Pancreatic Cancer
Studies have shown that injecting local anesthetics in areas rich in blood vessels increases the risk of drug injection into blood vessels by mistake and increases the systemic absorption of drugs, which may increase the…
- Trial name
- NCT03940027
- Testing
- EUS-guided celiac plexus neurolysis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital