Clinical trials: sponsored by Changhai Hospital
Bowel Preparation Scale, the Amount of Air Bubble
Premedication Simethione Improves Visibility During Bowel Cleansing for Colonoscopy
To evaluate the efficacy, visibility of low volume polyethyleneglycol-simeticone (2-LPEG-S) for colonoscopy.
- Conditions
- Bowel Preparation Scale, the Amount of Air Bubble, Adenoma Detection Rate
- Trial name
- NCT02540239
- Testing
- 2L PEG, 2L PEG+simethicone
- Where
- China
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Bowel Preparation Scale, Adenoma Detection Rate
Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy
In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 150) used 2 L PEG before colonoscopy.
- Trial name
- NCT02507037
- Testing
- gum+PEG, polyethylene glycol
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Carcinoma, Pancreatic Ductal
Safety and Efficacy Evaluation of iAPA-DC/CTL Combined Gemcitabine Therapy on Advanced Pancreatic Cancer
The aim of this study is to evaluate the safety and efficacy of iAPA-DC/CTL combined gemcitabine therapy on advanced pancreatic cancer.
- Trial name
- NCT02529579
- Testing
- iAPA-DC/CTL adoptive cellular immunotherapy, Gemcitabine
- Where
- China
- Volunteers
- 187 people
- Sponsor
- Changhai Hospital
Aortic Dissection
Glucocorticoid on the Prognosis of TEVAR
To explore the potential prognostic effect of glucocorticoid on the postoperative aorta-related adverse events after aortic dissections patients underwent thoracic endovascular aortic repair (TEVAR), glucocorticoid (30mg/kg) will…
- Trial name
- NCT02523300
- Testing
- TEVAR, Glucocorticoids, saline
- Volunteers
- 240 people
- Sponsor
- Changhai Hospital
Sepsis, Immunosuppression
Expression of TIM-3 on Lymphocytes in Sepsis
The current project was designed to examine the express TIM-3 on lymphocytes and monocytes and its role in immunosuppression during sepsis.
- Trial name
- NCT02319876
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Gastric Diseases,, Gastric Ulcer,
Magnetic-controlled Capsule Endoscopy vs. Gastroscopy for Detection of Gastric Diseases
A new Magnetic-controlled Capsule Endoscopy (MCE) was developed by ANKON and got SFDA's approval in China in 2013. It has recently been evaluated to compare the diagnostic accuracy of MCE with that of standard gastroscopy for…
- Conditions
- Gastric Diseases,, Gastric Ulcer,, Gastric Polyps,, Early Gastric Cancer,
- Trial name
- MCE (NCT02219529)
- Testing
- MCE, Standard gastroscopy
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Changhai Hospital
Gastric Symptoms, Indicated for Upper GI Endoscopy
Comparative Study of the Magnetic-controlled Capsule Endoscopy Versus Standard Gastroscopy
Passive video capsule endoscopy is the criterion standard for small-bowel diseases but cannot be used for the large gastric cavity.This blinded prospective study investigates the accuracy of the magnetic-controlled capsule…
- Trial name
- NCT01903629
- Testing
- MCE, Standard gastroscopy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Changhai Hospital
Colorectal Adenoma, Colorectal Polyp
Intubation Techniques on Colonoscopy Quality (SINOCOLO2013)
The primary aim of this study is to explore the usefulness of abdominal compression on intubation. Other aims include 1. to investigate the effectiveness and the efficacy of different manners of abdominal compression and to…
- Trial name
- SINOCOLO2013 (NCT01919463)
- Testing
- Abdominal Compression, Guidance of Magnetic Endoscopic Imaging (MEI) System
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Sepsis, Atrophy
HO-1 and Muscle Mitochondrial Dysfunction in Sepsis
The current project was designed to examine dynamic changes in muscle wasting during sepsis. Researchers will focus the mitochondrial dysfunction of muscle cells and investigate the role of HO-1 in it.
- Trial name
- NCT02359240
- Testing
- therapy according to SSC guidelines and muscle biopsy, standard surgery for femoral fracture and muscle biopsy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Pancreatic Stone Disease
Combination of Remifentanil and Flurbiprofen in Sedation and Analgesia for ESWL of Pancreatic Stone
Extracorporeal shock wave lithotripsy (ESWL) of pancreatic stones has been described as an effective approach for stone drainage and pain relief, and general or epidural anesthesia has been reported for such procedure.
- Trial name
- NCT01998217
- Testing
- Remifentanil, Flurbiprofen and remifentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital
Coronary Bypass Graft Stenosis of Autologous Vein
Preventing Seroma Formation After Stripping Saphenous Vein in Coronary Bypass
The great saphenous vein is the most commonly used material in coronary vascular bridging operation. Coronary bypass operation to obtain the great saphenous vein is mainly through the incision open groin to ankle.
- Trial name
- NCT02010996
- Testing
- vacuum assisted closure, Axillary dissection
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Changhai Hospital
Aortic Aneurysm, Aortic Aneurysm, Abdominal
Safety and Efficacy of Multiple Overlapping Uncovered Stents for Pararenal Aortic Aneurysm Repair
Complex aortic aneurysms involving major branches have been difficult endovascularly. The primary purposes of this study is to evaluate the safety, feasibility, and efficacy of multiple overlapping uncovered stents in treating…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Aortic Aneurysm, Thoracoabdominal
- Trial name
- SEMPER (NCT01985906)
- Testing
- Multiple overlapping uncovered stents, Uncovered stents
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Intestinal Diseases, Gastrointestinal Hemorrhage
Comparison of the Frequency-altering AKE-1 Capsule and Pillcam SB2
Capsule endoscopy has been shown to be the first-line endoscopic procedure for small bowel disease. This study was aimed to compare the performance between the frequency-altering AKE-1 capsule and the Pillcam SB2 in patients with…
- Trial name
- NCT01872286
- Testing
- AKE-1, Pillcam SB2
- Where
- 2 sites in China
- Volunteers
- 53 people
- Sponsor
- Changhai Hospital
Chronic Erosive Gastritis
A Study to Evaluate the Efficacy of Teprenone On Chinese Patients With Chronic Non-Atrophic Erosive Gastritis
The purpose of this study is to evaluate the efficacy of teprenone on chronic non-atrophic erosive gastritis and its therapeutic mechanism
- Trial name
- NCT01284647
- Where
- 8 sites in China
- Volunteers
- 156 people
- Sponsor
- Changhai Hospital
Acute Myeloid Leukemia, AML1-ETO Fusion Protein Expression
AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy
The purpose of the study is to determine whether Fludarabine in combination with cytarabine is more effective than high-dose cytarabine in post-remission therapy for patients with AML1-ETO acute myeloid leukemia.
- Trial name
- NCT02024308
- Testing
- Fludarabine, Cytarabine
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Changhai Hospital
Parkinson's Disease
Requirement of Propofol for Induction of Unconsciousness in Patients With Parkinson's Disease
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease. The investigators clinical experience showed a trend of delayed emergence among patients undergoing deep brain stimulator (DBS) implantation and…
- Trial name
- NCT01998204
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Changhai Hospital
Sepsis
HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis
Molecules indicating endothelial injury may serve as biomarkers for severe sepsis because of the critical role of endothelial injury in organ dysfunction during severe sepsis.
- Trial name
- NCT01847248
- Where
- China
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Parkinson's Disease
Remifentanil Requirement in Patients Receiving Surgical Treatment of Parkinson's Disease
Parkinson's disease (PD) is one the main neurodegenerative disease with an incidence of about 3% in patients older than 65 years.
- Trial name
- NCT01992692
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Changhai Hospital
Sepsis, Immunosuppression
Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis
Immunosuppression is the leading cause of death in septic patients. Neutrophils are classical components of innate immunology, but recent studies showed that neutrophils might display antigen presenting function and inhibit…
- Trial name
- NCT01976884
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Distal Aortic Dissection
A Multi-center Trial of Single-Branched Stent Graft System to Treat Aortic Dissection
Aim:Castor is a novel single-branched stent graft system for endovascular repair of aortic arch dissection. This is a prospective, one-arm, open, multi-center, pre-market study of Castor stent to evaluate its efficacy and safety…
- Trial name
- NCT01914237
- Testing
- Castor Stent Graft
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Changhai Hospital