Clinical trials: sponsored by Changhai Hospital
Single Nucleotide Polymorphism, Acute Lung Injury
Nuclear Factor Kappa-B (NFKB1) Polymorphism and Organ Injury After Cardiac Surgery
NFKB1 -94ins/del polymorphism has been reported to be associated with reduced promoter activity of NFKB1 and several clinical diseases, but the clinical results cannot always be replicated.
- Conditions
- Single Nucleotide Polymorphism, Acute Lung Injury, Kidney Injury
- Trial name
- NCT00819871
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Changhai Hospital
Acute Lung Injury
Inflammatory Genetic Polymorphism and Acute Lung Injury After Cardiac Surgery
Acute lung injury is a common complication of cardiac surgery with cardiopulmonary bypass, and it is significantly related to prolonged postoperative recovery, hospital stays and medical cost.
- Trial name
- NCT00826072
- Where
- China
- Volunteers
- 107 people
- Sponsor
- Changhai Hospital
Sepsis
Circulating microRNAs as Biomarkers of Sepsis
MicroRNA has been demonstrated to play a crucial role in regulating cell processes. Recently, microRNA was identified to exist in human serum or plasma, and it might be related to certain diseases.
- Trial name
- NCT00862290
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Endoscopic Retrograde Cholangiopancreatography, Bile Duct Diseases
Compare the Knob-tipped Knife With the Needle Knife in Difficult Biliary Cannulation
The aim of the present study was to compare the efficacy and safety of the knob-tipped knife and needle knife for precut papillotomy in difficult common bile duct (CBD)cannulation.
- Trial name
- NCT01745978
- Testing
- Precut papillotomy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Breast Neoplasms
Preventing Seroma Formation After Axillary Lymph Node Dissection for Breast Cancer by Early Vacuum Assisted Closure
Axillary dissection is the standard treatment for breast cancer patients with positive nodes. However, seroma formation after axillary dissection remains the most common early complication to breast cancer surgery.
- Trial name
- NCT01731769
- Testing
- vacuum assisted closure in experimental arm, Axillary dissection
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Obesity, Overweight
Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers
The purpose of the study is to determine whether calcium plus vitamin D supplementation is conducive to weight and fat loss during energy restriction in very-low calcium consumers.
- Trial name
- NCT01447433
- Testing
- Calcium Carbonate, Energy restriction
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Australia Antigen Positive, Hepatitis B
Optimization of Antiviral Therapy of Chronic HBV Infection
Along with the improvement of the accuracy of detection of HBV serological markers, the optimization of antiviral therapy for patients with chronic hepatitis B (CHB) infection becomes feasible.
- Conditions
- Australia Antigen Positive, Hepatitis B, Adverse Effects
- Trial name
- NCT01623778
- Testing
- Interferon Alfa-2a add on ADV
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Changhai Hospital
Post-ERCP Acute Pancreatitis
The Prophylactic Effect of Stilamin on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Pancreatitis are one of the most common complications of post-ERCP (Endoscopic Retrograde Cholangiopancreatography), the incidence rate is 5\&-10%, how to prevent PEP and hyperamylasemia is an important issue, somatostatin is…
- Trial name
- NCT01431781
- Testing
- Stilamin+common daily treatment, Common daily practice
- Where
- 15 sites in China
- Volunteers
- 908 people
- Sponsor
- Changhai Hospital
Antibiotic-associated Diarrhea
Dose Response Effect of Probiotics for the Prevention of Antibiotic-associated Diarrhea in Chinese Adults
The purpose of this study is to determine the dose response effect of probiotic capsules for the prevention of antibiotic-associated diarrhea (AAD).
- Trial name
- NCT01143623
- Testing
- Probiotic
- Where
- China
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Hepatoma, Cinobufacin Injection
Study of Hepatoma Treated by Perfusing Cinobufacin Through Hepatic Artery Combining Embolotherapy
Cinobufacini has the effects of anticancer, improving the liver function, elevation of immunity and little side effects, and is important and significant for the patients with hepatitis, liver cirrhosis and hepatomas.
- Trial name
- NCT01236690
- Testing
- Cinobufacin injection
- Where
- China
- Volunteers
- 284 people
- Sponsor
- Changhai Hospital
Cholangiocarcinoma
Unilateral Versus Bilateral Stents for Bismuth Type II and III Malignant Hilar Strictures
The aim of the present study was to compare the effect of unilateral versus bilateral stenting in patients with malignant hilar obstruction.
- Trial name
- NCT00653978
- Testing
- ERCP plus one biliary stent, ERCP plus two biliary stents
- Where
- 2 sites in China, Slovakia
- Volunteers
- 150 people
- Sponsor
- Changhai Hospital
ERCP, Pancreatic Diseases
Drotaverine Hydrochloride Versus Hyoscine-N-butylbromide for Duodenal Antimotility During Endoscopic Retrograde Cholangiopancreatography (ERCP)
The aim of the present study was to evaluate the use of drotaverine hydrochloride versus hyoscine-N-butylbromide in reducing duodenal motility during diagnostic and therapeutic ERCP.
- Conditions
- ERCP, Pancreatic Diseases, Bile Duct Diseases
- Trial name
- NCT00731198
- Testing
- Drotaverine hydrochloride, Hyoscine-N-butylbromide
- Where
- 4 sites in China
- Volunteers
- 650 people
- Sponsor
- Changhai Hospital
Acute, Pancreatitis
Soluble Triggering Receptor Expressed on Myeloid Cells in Severe Acute Pancreatitis
Early diagnosis of secondary infection of necrotic tissue in severe acute pancreatitis is extremely important. The investigators evaluated whether the level of soluble TREM-1 (sTREM-1) in fine needle aspiration (FNA) fluid from…
- Trial name
- STREM-1 (NCT01193413)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Changhai Hospital
Sepsis
PD-1/PD-L1 Pathway Study on Septic Patients
The investigators want to identify that whether PD-1/PD-L1 pathway will change in human sepsis, and whether PD-1/PD-L1 pathway play an important role in sepsis induced immunosuppression.
- Trial name
- NCT01161745
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Healthy
FCM Analysis GR in Steroid-Treatment Patients
Monitoring the GR with a GR-MoAb and FITC-Dex probes by FCM would be useful and convenient in determination GR before the steroid treatment in clinical, especially in steroid resistant states, in order to design more efficient…
- Trial name
- NCT00600652
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital