Clinical trials: sponsored by Changhai Hospital
Acute Ischemic Stroke, Large Vessel Occlusion
Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study
A Multicenter Registry of Endovascular Treatment for Acute Ischemic Stroke.
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- NCT05864638
- Testing
- Endovascular treatment
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Changhai Hospital
Cerebral Aneurysm Unruptured, Cerebral Aneurysm
Parent Artery Reconstruction for Small Unruptured Cerebral Aneurusms Using Flow DiverTers: a Multicenter Randomized Trial(PARAT-MT)
A prospective, multicenter, randomized controlled clinical trial with open-label treatment and blinded endpoint assessment.
- Trial name
- NCT06600997
- Testing
- Flow Diversion for Endovascular Treatment of Intracranial Aneurysms, Conventional endovascular therapy (stent-assisted coiling, balloon-assisted coiling, or coiling) for endovascular treatment of intracranial aneurysms
- Volunteers
- 1,008 people
- Sponsor
- Changhai Hospital
Bowel Preparation for Colonoscopy
Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing
Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy.
- Trial name
- NCT06728839
- Testing
- 1L PEG + 50g magnesium sulfate, 3L PEG, 4L PEG
- Volunteers
- 1,329 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Acute Upper Gastrointestinal Bleeding, Capsule Endoscopes
Detachable String Magnetically Controlled Capsule Endoscopy for Patients with AUGIB
Use CE for pre-examination of patients with AUGIB symptoms in emergency centers may reduce the need for emergency electronic gastroscopy and have certain advantages in clinical work.
- Trial name
- NCT06725056
- Testing
- DS-MCE and EGD examinations
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital
Gastrointestinal Bleeding, Antiplatelet Therapy
MCE Identifying Bleeding Lesions in Patients with Antiplatelet Drugs-Related Acute Non-Hematochezia Gastrointestinal Bleeding
The goal of this clinical trial is to explore the diagnostic efficacy of detachable string magnetically controlled capsule endoscopy (ds-MCE) for identification of bleeding lesions in patients with antiplatelet drugs-related…
- Trial name
- MCE (NCT06698874)
- Testing
- ds-MCE and EGD examinations
- Where
- 4 sites in China
- Volunteers
- 204 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Study on Predictive Factors, Safety and Efficacy of Endoscopic Retrograde Accessory Pancreatography in CP
Chronic pancreatitis (CP) can manifest characteristic pathological modifications such as pancreatic duct stenosis and pancreatic duct lithiasis.
- Trial name
- NCT06684301
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Coronary Artery Disease
Carotid Plaque Length to Predict Cardiovascular Events
This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No.
- Trial name
- NCT05409209
- Where
- 5 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Changhai Hospital
Localized Prostate Cancer
Radical Hypofractionated Radiotherapy for Localized Prostate Cancer
The aim of this trial is to study the safety outcomes of hypofractionated radiotherapy in treating patients with localized prostate cancer.
- Trial name
- NCT06325774
- Testing
- Hypofractionated radiation therapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Changhai Hospital
Localized Prostate Cancer
Hypofractionated Post-prostatectomy Radiotherapy (HYPORT)for Localized Prostate Cancer
The aim of this trial is to compare the safety outcomes of Hypofractionated postprostatectomy radiotherapy (HYPORT) and Conventionally fractionated postprostatectomy radiotherapy(COPORT) in treating patients with localized…
- Trial name
- NCT06325995
- Testing
- Conventional radiation therapy, Hypofractionated radiation therapy
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Changhai Hospital
Rectum Cancer
Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer
In this clinical trial, the investigators compared anal function, genitourinary function, quality of life, perioperative safety, and oncological prognosis after CSPO for patients with low rectal cancer, using ISR as a control, to…
- Trial name
- NCT06567756
- Testing
- CSPO, ISR
- Volunteers
- 84 people
- Sponsor
- Changhai Hospital
Radiotherapy
Chemoradiotherapy After Surgery Versus Preoperative Chemoradiotherapy for Stage II/III Mid-low Rectal Cancer With or Without High-risk Factors
The purpose of this observational study is to understand the effect of different timing of chemoradiotherapy on overall survival in patients with stage II/III low- and medium-level rectal cancer with or without high-risk factors
- Trial name
- NCT06566222
- Testing
- chemoradiotherapy after surgery, High-risk Factors
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Exercise Inhibit Innate Immune Response and Ameliorate Chronic Pancreatitis
The goal of this observational study is to learn about the effects of different physical exercise on disease progression in patients with chronic pancreatitis.
- Trial name
- NCT06534138
- Testing
- Physical exercise
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Changhai Hospital
Non-Small Cell Lung Cancer
High-dose Furmonertinib in the Treatment in Patients With Advanced, Metastatic NSCLC With Progressed After First- or Second-line Treatment With Osimertinib
This is a prospective, randomised, uncontrolled phase II clinical trial planned to include 84 subjects with metastatic lung adenocarcinoma that had progressed after first- or second-line treatment with Osmertinib, who were…
- Trial name
- NCT06394674
- Testing
- Furmonertinib
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Changhai Hospital
Early Esophageal Cancer
China Early Esophageal Cancer Cohort
With the development of endoscopy, more and more patients with superficial esophageal squamous cell carcinoma (ESCC) receive endoscopic resection rather than traditional surgery.
- Trial name
- NCT06515964
- Testing
- observational study
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Changhai Hospital
Adenoma, Sessile Serrated Adenoma
Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions
Texture and Color Enhancement Imaging (TXI) is a newly developed image-enhancing endoscopy technology that has show potential in improving detection of colorectal lesions.
- Trial name
- NCT06515977
- Testing
- TXI (Group A), TXI followed by WLI (Group B), WLI (Group C)
- Volunteers
- 2,964 people
- Sponsor
- Changhai Hospital
Inflammatory Bowel Diseases
Vitamin B6 Aids in Treating Inflammatory Bowel Disease
Patients with IBD are randomized to oral administration of VitaminB6 and placebo based on the standard treatment, exploring whether VitaminB6 can increasee the clinical remission rateand improve the treatment effect of IBD…
- Trial name
- NCT06512441
- Testing
- Vitamin B6 Tablets
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Changhai Hospital
Inflammatory Bowel Diseases
Mobile App-Based Remote Management Model for IBD Patient
Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition of the intestines, with its incidence showing a significant year-on-year increase in China.
- Trial name
- NCT06512792
- Testing
- Telemedicine management through Mobile APP
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Changhai Hospital
Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease Diagnostic Trial
Gastroesophageal reflux disease (GERD) is a very common condition in clinical practice. In China, GERD affects nearly 150 million patients, whose quality of life are seriously impacted.
- Trial name
- GERDT (NCT06504134)
- Testing
- the Novel Esophageal Cell Collection Device
- Volunteers
- 1,000 people
- Sponsor
- Changhai Hospital
Acute Ischemic Stroke, Large Vessel Occlusion
Proximal TEmporary oCclusion Using Balloon Guide Catheter for Mechanical Thrombectomy
A multi-center, prospective, randomized, open-label, blinded endpoint assessment (PROBE) clinical trial of endovascular treatment among selected AIS.
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- PROTECT-MT (NCT05592054)
- Testing
- Balloon guide catheters (BGCs), Standard guide catheter
- Where
- China
- Volunteers
- 329 people
- Sponsor
- Changhai Hospital
Recurrent Acute Pancreatitis
Efficacy of ERCP in the Diagnosis and Treatment of Idiopathic Recurrent Acute Pancreatitis
The goal of this clinical trial is to learn if endoscopic retrograde cholangiopancreatography (ERCP) works to treat idiopathic recurrent pancreatitis (IRAP) in adults.
- Trial name
- ESPRIT (NCT06364397)
- Testing
- ERCP, Health education and conservative management of clinical routines
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Changhai Hospital