Clinical trials: sponsored by Changhai Hospital
Pancreatic Duct Stone
Safety and Efficacy of P-ESWL and ERCP
To determine the types, incidence and risk factors of adverse events after pancreatic extracorporeal shock wave lithotripsy (P-ESWL) and endoscopic retrograde cholangiopancreatography (ERCP), define the grading criteria of…
- Trial name
- NCT05916547
- Testing
- pancreatic extracorporeal shock wave lithotripsy
- Where
- China
- Volunteers
- 2,071 people
- Sponsor
- Changhai Hospital
Long COVID, Post-Acute COVID-19 Syndrome
Effectiveness and Safety of Mesenchymal Stem Cell Therapy in Long COVID Patients
The goal of this clinical trial is to evaluate the effectiveness and safety of mesenchymal stem cell therapy in long-COVID patients.
- Trial name
- NCT06492798
- Testing
- umbilical cord mesenchymal stem cell
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Changhai Hospital
Hematuria, Urothelial Carcinoma
Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria
Background Urothelial carcinoma (UC) is the most common malignancy of the urinary system. Hematuria is a significant clinical manifestation of UC, often diagnosed through invasive procedures.
- Conditions
- Hematuria, Urothelial Carcinoma, Bladder Cancer, Ureter Cancer
- Trial name
- NCT06469229
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Changhai Hospital
Bowel Preparation for Colonoscopy
Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy
The clinical purpose of this study was to investigate whether the adjuvant application of linaclotide in bowel preparation for colonoscopy could improve the quality of bowel preparation or reduce the dosage of laxatives.
- Trial name
- NCT05291325
- Testing
- 3L PEG + Linaclotide, 3L PEG, 2L PEG + Linaclotide
- Where
- China
- Volunteers
- 1,607 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Hematuria, Urothelial Carcinoma
Urine DNA Methylation Detection for Hematuria Evaluation
Background: Hematuria, a common symptom of urinary system diseases, can result from various causes including infection, stones, trauma, and tumors.
- Conditions
- Hematuria, Urothelial Carcinoma, Bladder Cancer, Ureter Cancer
- Trial name
- NCT06427993
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Changhai Hospital
Esophageal Squamous Cell Carcinoma
Cytosponge in Surveillance After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma
cytosponge has good diagnostic efficacy in the diagnosis of esophageal cancer, and is more safe, economic and comfortable. It is expected to replace gastroscope in the surveillance after endoscopic submucosal dissection to a…
- Trial name
- NCT06429865
- Testing
- cytosponge
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Changhai Hospital
Pancreatic Cancer
Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)
In the case of large tumors or tumors closely adjacent to organs at risk, ablative doses offered by stereotactic body radiation therapy (SBRT) could not be delivered.
- Trial name
- NCT06427460
- Testing
- Central-boost ablative dose delivered by stereotactic body radiation therapy
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Changhai Hospital
Pancreatectomy
Methods of Pancreatic Stump Closure for Distal Pancreatectomy
The aim of this study is to conduct a retrospective analysis of patients who underwent distal pancreatectomy in our hospital, aiming to evaluate the safety and feasibility of two methods for closure of the pancreatic remnant…
- Trial name
- NCT06424431
- Testing
- stapler combined with electrocautery, simple closure with a closure device
- Where
- China
- Volunteers
- 487 people
- Sponsor
- Changhai Hospital
Clinical Study, Chronic Functional Constipation
Real-World Clinical Study on the Efficacy of Vibrating Capsule (Vibrabot Capsule) for Chronic Functional Constipation
This study is a multi-center prospective cohort study, which plans to include 300 patients with chronic functional constipation to treat with Vibrabot capsules, and at the same time, include ≥300 patients receiving constipation…
- Trial name
- RWS-VC (NCT06418685)
- Testing
- Treatment with Vibrating Capsule
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Esophageal Neoplasms Malignant
Multimodal Endoscopic Image Fusion for Assessing Infiltration in Superficial Esophageal Squamous Cell Carcinoma
The objective of this project is to pioneer a novel protocol for the adjunctive screening of early-stage esophageal cancer and its precancerous lesions.
- Trial name
- NCT06412419
- Testing
- Magnifying Endoscopy and Endoscopic Ultrasonography
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Changhai Hospital
Pancreatic Cancer, Chronic Pancreatitis
Gastrointestinal Microflora and Serum Metabolomics in Patients With Pancreatic Cancer and Chronic Pancreatitis
The investigators plan to collect throat swabs, saliva, feces and serum samples from pancreatic cancer patients, chronic pancreatitis patients and healthy people and clarify the characteristics of oral flora and serum metabolome…
- Trial name
- NCT06411470
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Clinical Study, Chronic Functional Constipation
Effect of Vibration Capsule on Different Subtypes of Functional Constipation
This study is a multi-center prospective cohort study, which plans to include 600 patients with chronic functional constipation to treat with Vibrabot capsules and patients will be grouped according to subtypes.
- Trial name
- NCT06408883
- Testing
- Vibrabot capsule
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Changhai Hospital
Cohort Study, Recurrent Acute Pancreatitis
Natural Course and Therapeutic Effect of Recurrent Acute Pancreatitis
The goal of this observational cohort study is to learn about the etiology, natural course, therapeutic effect and outcome of recurrent acute pancreatitis patients.
- Trial name
- NACRE (NCT06355206)
- Testing
- endoscopic intervention, surgery or conservative treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Diagnoses Disease
Establish Diagnostic Models Based on Portal Venous Blood for Pancreatic Cancer
Explore new markers based on portal venous blood sampling to establish novel diagnostic models for identification of malignant pancreatic mass.
- Trial name
- NCT04536220
- Testing
- Endoscopic Ultrasound (EUS), Fine Needle Aspiration
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Prostate Cancer
Adjuvant Hypofractionated Radiotherapy for Prostate Cancer
Hypofractionated radiation therapy is a new type of radiotherapy which has been shown to play a larger role in the treatment of prostate cancer.
- Trial name
- NCT06335693
- Testing
- Radiotherapy
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Changhai Hospital
Colonoscopy: Bowel Preparation
Efficacy of Short Time Intervals in Split-Dose Bowel Preparation of Oral Sulfate Solution for Colonoscopy
To evaluate whether oral sulfate solution administered in a short time interval (6-8 hours) between the first and last dose of laxative is not inferior to a long time interval (10-12 hours) in bowel preparation quality.
- Trial name
- NCT06317597
- Testing
- Magnesium Sulfate，Sodium Sulfate and Potassium Sulfate Concentrate Oral Solution
- Where
- China
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Sessile Serrated Lesion
Narrow Band Imaging Versus White Light for the Detection and Miss of Sessile Serrated Lesion
Narrow band imaging(NBI) could improve the detection of colorectal lesions, previous investigations demonstrated its potential in detecting not only colorectal adenoma but non-adenomatous polyps, including sessile serrated…
- Trial name
- NCT05684328
- Testing
- WLI Then NBI Withdrawal, NBI Then WLI Withdrawal
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Changhai Hospital
Neoadjuvant Radiotherapy, Breast Cancer
Neoadjuvant Radiotherapy for Breast Cancer
The goal of this clinical trial is to compare the effects of neoadjuvant radiotherapy and adjuvant radiotherapy in patients with breast cancer.
- Trial name
- NCT06313073
- Testing
- Neoadjuvant radiotherapy, adjuvant radiotherapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis, Exocrine Pancreatic Insufficiency
AI Evaluation of Pancreatic Exocrine Insufficiency in CP Patients
Early assessment of pancreatic exocrine insufficiency (PEI) is crucial for determining appropriate chronic pancreatitis (CP) treatment plans, thereby avoiding unnecessary suffering and further complications in patients.
- Conditions
- Chronic Pancreatitis, Exocrine Pancreatic Insufficiency, Machine Learning, Deep Learning
- Trial name
- NCT06278272
- Where
- China
- Volunteers
- 504 people
- Sponsor
- Changhai Hospital
Oligometastatic Prostate Carcinoma
Neoadjuvant Radiohormonal Therapy for Oligometastatic Prostate Cancer
The optimal treatment for oligometastatic prostate cancer (OMPC) is still on its way. Accumulating evidence has proven the safety and feasibility of radical prostatectomy and local or metastasis-directed radiotherapy for…
- Trial name
- NCT05707468
- Testing
- ADT combined with abiraterone, neoadjuvant hormone and RT
- Where
- 6 sites in China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital