Clinical trials: completed, sponsored by Duke University
Cardiovascular Disease, HIV
Case Managers for CVD Risk Reduction in HIV Clinic
The purpose of the study is to assess the efficacy of a case manager/social worker administered, telephone-based educational curriculum in improving cardiovascular disease related outcomes among HIV-infected clinic patients.
- Trial name
- NCT03839394
- Testing
- Telephone, Educational pamphlets
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Heart Failure, Type 2 Diabetes
Optimizing In-hospital Use of Evidence-based Therapies for Patients With Cardio-Renal-Metabolic Disease
This study will be a prospective randomized implementation trial for patients hospitalized with heart failure, chronic kidney disease, and/or type 2 diabetes mellitus within Duke University Medical Center.
- Conditions
- Heart Failure, Type 2 Diabetes, Chronic Kidney Diseases
- Trial name
- IMPLEMENT-CRM (NCT05781334)
- Testing
- Virtual Consult Intervention
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Duke University
Dementia
Family Involvement Hospital Ethnography
The goal of this observational study is to learn about the role of family members in caring for hospitalized older adults with cognitive impairment. The main questions it aims to answer are: 1.
- Trial name
- NCT06374992
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Duke University
Head and Neck Cancer, Oral Cancer
Low-Cost, Portable Flexible Nasopharyngoscope in Head & Neck Cancers in Low Resource Settings - Optimization Phase
This study aims to develop and evaluate a low-cost, portable, flexible nasopharyngeal scope (FNS) used to assess head and neck cancers (HNC) in low resource settings.
- Trial name
- NCT04905134
- Testing
- Nasopharyngoscope
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Mild Cognitive Impairment, Alzheimer Disease
Effect of Blueberry Supplementation on Alzheimer's Biomarkers
The purpose of this study is to study the effects of blueberries on neuronal, glial, and pathology blood biomarkers in Mild Cognitive Impairment (MCI) and to estimate sample size for future confirmatory studies.
- Trial name
- NCT05172128
- Testing
- lyophilized blueberry supplement
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Covid19
Balance Function in Patients Post Corona Virus Disease 2019 (COVID-19)
The purpose of this study is to describe balance deficits in patients post COVID-19. The information the investigators learn may help influence balance training exercises for patients post-COVID-19.
- Trial name
- NCT04914364
- Testing
- Balance assessments
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Glaucoma
The Baerveldt Versus ClearPath Comparison Study
This is a randomized prospective study of post-operative surgical outcomes and complication rates in patients with a Baerveldt 350 implant vs the Ahmed ClearPath implant.
- Trial name
- NCT04468633
- Testing
- Baerveldt 350 implant, Ahmed ClearPath 350 implant
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Duke University
Hypertension, Health Behavior
Nourish: A Digital Health Program to Promote the DASH Eating Plan Among Adults With High Blood Pressure
The goal of Nourish is to help adults with high blood pressure enjoy an eating pattern called DASH (Dietary Approaches to Stop Hypertension) to lower blood pressure and improve health.
- Trial name
- NCT03875768
- Testing
- Tracking plus coaching
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Duke University
Cardiorespiratory Failure
Optimizing a Mobile Mindfulness Intervention for ICU Survivors
This is a factorial experimental trial involving adult survivors of cardiorespiratory failure treated in intensive care units (ICUs) that is conceptualized as the Optimization Phase of a multiphase optimization strategy (MOST)…
- Trial name
- LIFT2 (NCT04038567)
- Testing
- Mobile mindfulness-based training
- Where
- 3 sites in United States
- Volunteers
- 247 people
- Sponsor
- Duke University
Parkinson Disease
The Benchmark Clinic: An Interdisciplinary Comprehensive Care Model for People With Parkinson Disease
The purpose of this study is to determine if an interdisciplinary clinic can help people with Parkinson's disease care for themselves, improve their ability to follow recommended treatments, and have fewer problems like falls or…
- Trial name
- NCT04555720
- Testing
- Interdisciplinary Visit
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Duke University
Child Rearing, Mental Health Wellness 1
National Evaluation of Quality of Childcare (C0682)
This evaluation seeks to assess the impact of a training program on childcare center environments and child/caregiver wellbeing in El Salvador.
- Conditions
- Child Rearing, Mental Health Wellness 1, Health Behavior
- Trial name
- ENCCI (NCT02534597)
- Testing
- Promotores Training, Delayed Promotores training, Caregiver training
- Where
- El Salvador
- Volunteers
- 1,923 people, healthy volunteers welcome
- Sponsor
- Duke University
Glioblastoma
Glioblastoma Psychosocial Support Program
The goal of the study is to conduct a pilot test of the psychosocial support intervention with family caregivers and/or patients coping with glioblastoma.
- Trial name
- NCT06038604
- Testing
- Psychosocial Support Intervention
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
ADHD, Psychiatric Health
El Faro: Addressing Mental Health Inequities Among Latinx Children With ADHD in Durham
Study team members from El Futuro in Durham, North Carolina have created an intervention called El Faro. El Faro helps Latinx families of children with ADHD understand and cope with the stress and difficulties presented by the…
- Trial name
- NCT05928182
- Testing
- El Faro Treatment Intervention
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Duke University
HIV, Trauma Exposure
Improving the Health of South African Women With Traumatic Stress in HIV Care (C0147)
In this study, the investigators propose to develop Improving AIDS Care after Trauma (ImpACT), an intervention based on theories of stress and coping and evidence-based treatment for traumatic stress.
- Trial name
- ImpACT (NCT02223390)
- Testing
- Improving AIDS Care after Trauma (ImpACT)
- Where
- South Africa
- Volunteers
- 64 people
- Sponsor
- Duke University
Cervical Cancer, HPV Infection
Identification and Treatment of Cervical Abnormalities in Perú Through Integration of Pocket Colposcopy and Telemedicine
The Pocket colposcope has 510k FDA clearance and has been successfully used in almost 1500 unique patients globally in Duke and non-Duke protocols to date.
- Conditions
- Cervical Cancer, HPV Infection, HIV Infections
- Trial name
- NCT05340322
- Testing
- Colposcopy using pocket colpscope and thermocoagulator
- Where
- Peru
- Volunteers
- 503 people
- Sponsor
- Duke University
Traumatic Brain Injury
In-Field Detection of Intracranial Pressure
This is a research study to develop a noninvasive test using ultrasound to determine when urgent, life-saving treatment is needed for those with severe traumatic brain injuries.
- Trial name
- NCT04515212
- Testing
- Optic Nerve Ultrasounds
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Duke University
Depression, Anxiety
Outcomes of a Self-guided Versus Therapist-guided Online Mental Health Treatment
This is a pilot study of an online mental health treatment. The goals of the study are to determine the feasibility of an online treatment for depression and anxiety symptoms with little-to-no human support, in a sample of 50…
- Conditions
- Depression, Anxiety, Mood
- Trial name
- NCT04810988
- Testing
- Unified Protocol, Therapist Support
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Total Shoulder Arthroplasty, Rotator Cuff Tears
Ultrasound After Total Shoulder Arthroplasty
The purpose of this study would be to evaluate a group of patients status post post-total shoulder arthroplasty to assess the integrity of the rotator cuff using ultrasound.
- Conditions
- Total Shoulder Arthroplasty, Rotator Cuff Tears, Rotator Cuff Injuries
- Trial name
- NCT04416932
- Testing
- Ultasound
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Smokeless Tobacco Cessation
A Text-based Reduction Intervention for Smokeless Tobacco Cessation
Participants will be randomly assigned (like the flip of a coin) to one of the two groups after completing the baseline survey. Participants have a 50% of being in either the #EnufSnuff.TXT intervention group or the Enough Snuff…
- Trial name
- NCT04315506
- Testing
- #EnufSnuff.TXT Intervention, Enough Snuff Intervention
- Where
- United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Duke University
Parenting, Child Abuse
Parents Make the Difference II: Trial of a Parenting Intervention
Multisite randomized trial of a parenting intervention in Liberia for caregivers of young children. Two main objectives of the "Parents Make the Difference" program are to teach parents (a) skills for decreasing harsh punishments…
- Trial name
- PMD2 (NCT02852291)
- Testing
- Parents Make the Difference, Parents Make the Difference Plus
- Where
- Liberia
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Duke University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.