Clinical trials: completed, sponsored by Duke University
Dynapenia, Obesity
An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition
The purpose of the trial is to assess the effects of combining regular, generous intakes of high quality protein (primarily from dairy and other animal source proteins) with calorie restriction and low-intensity exercise on…
- Trial name
- DDYNAMO (NCT02437643)
- Testing
- Weight Loss, Dairy Protein, Low intensity exercise
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Duke University
Childhood Leukemia
Symptom Clusters in Children With Leukemia
The purpose of this study is to examine the phenotypic and genotypic characteristics and their associations with symptom clusters experienced during treatment for childhood leukemia.
- Trial name
- NCT01708421
- Where
- 4 sites in United States
- Volunteers
- 338 people
- Sponsor
- Duke University
Unresectable Melanoma
Trial of Neoadjuvant Ipilimumab Followed by Melphalan Via Isolated Limb Infusion for Patients With Unresectable In-transit Extremity Melanoma
The purpose of this study is to determine safety profile, initial response rates and progression free survival for the combination therapy of neoadjuvant system ipilimumab followed by ILI with melphalan in patients with in…
- Trial name
- NCT02115243
- Testing
- Ipilimumab
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Duke University
Rheumatoid Arthritis
Coping Skills Training for Early Rheumatoid Arthritis
Rheumatoid arthritis (RA) is the most common inflammatory arthritis and a major health problem. Medical treatments are now being used much earlier in the course of RA, but these treatments do not address the challenges of coping…
- Trial name
- NCT00056394
- Testing
- Comprehensive Coping Skills Training, Arthritis Education Sessions, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Duke University
Osteoarthritis
Weight Management and Coping Skills Training For Patients With Knee Osteoarthritis
Osteoarthritis (OA) occurs when the cartilage between two bones becomes worn down, and the bones begin to rub against each other in the joint.
- Trial name
- NCT00305890
- Testing
- Lifestyle Behavioral Weight Management Program, Pain-Coping Skills Training, Standard Care
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Duke University
Cancer of the Gastrointestinal, Genitourinary or Gynecologic Systems
Real Time In-Vivo Body Surface Dosimetry for External Beam Radiation Therapy
This is an observational study. This protocol will determine the feasibility of using a novel nano-material based fiber-optic dosimeter (nanoFOD) device, with dimensions less than 1 mm wide, to measure real-time, pin-point…
- Trial name
- NCT02407977
- Testing
- Novel nano-scintillatorfiber-optic dosimeter ( nanoFOD)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Duke University
Hepatitis C, Chronic; AUD
Hepatitis C Alcohol Reduction Treatment
Subjects are being asked to take part in a research study to test two levels of alcohol services for patients with hepatitis C virus (HCV) who drink alcohol.
- Trial name
- HepART-RCT (NCT02176980)
- Testing
- Brief alcohol counseling, Group and Individual Therapy Sessions
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Duke University
Prostate Cancer
Carbohydrate Restriction and Prostate Cancer Growth
No treatments have been shown to slow prostate cancer progression after radical prostatectomy. We hypothesize that a carbohydrate restricted diet will slow prostate cancer growth.
- Trial name
- CAPS2 (NCT01763944)
- Testing
- Low carbohydrate diet
- Where
- 3 sites in United States
- Volunteers
- 83 people
- Sponsor
- Duke University
Advanced Breast Cancer Stage IV
Self-management Interventions for Advanced Breast Cancer
The purpose of this research study is to evaluate whether self-management discussion groups are helpful for women with advanced breast cancer who are experiencing pain.
- Trial name
- NCT01927081
- Testing
- discussion group, gentle exercise
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Duke University
Asthma
PackHealth: Asthma Engagement Tool
The purpose of this study is to test the impact of an innovative patient engagement solution on patient's quality of life and asthma-related outcomes, and evaluate the correlation between a patient reported outcome measure and…
- Trial name
- NCT02413684
- Testing
- Patient engagement toolkit
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Chronic Kidney Disease
Is There a Digital Divide in Chronic Kidney Disease (CKD)?
This study is looking to improve the safety of patients with chronic kidney disease via education provided on a mobile tablet. This study will additionally examine if electronic tools, such as mobile tablets, can help.
- Trial name
- eCRIC (NCT03067779)
- Testing
- mHealth Tool
- Where
- 4 sites in United States
- Volunteers
- 580 people
- Sponsor
- Duke University
Breast Cancer
Improving Adherence to Recommended Surveillance in Breast Cancer Survivors
Evidence-based guidelines recommend cancer surveillance procedures for breast cancer survivors including physical examination, mammography, breast self-exam, and gynecologic follow-up.
- Trial name
- NCT02189278
- Testing
- Psychosocial Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Prematurity, Anemia
Transfusions and Nitric Oxide Level in Preterm Infants
The purpose of this study is to better understand S-nitrosohemeglobin (SNO-Hb) in transfused blood of extremely preterm infants.
- Conditions
- Prematurity, Anemia, Necrotizing Enterocolitis
- Trial name
- NCT00787124
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Duke University
Obesity
New Media Obesity Treatment in Community Health Centers
This purpose of this trial is to determine whether a 12-month eHealth behavioral intervention that includes interactive self-monitoring and feedback, tailored skills training materials, telephone counseling calls, and primary…
- Trial name
- NCT01827800
- Testing
- eHealth weight loss intervention
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- Duke University
Breast Cancer
Feasibility of Blood Oxygenation Level-Dependent Contrast (BOLD) Breast MRI Induced by Breath- Holding
In this study, investigators intend to measure changes in BOLD contrast in the breast induced by breath-holding for subjects receiving radiation therapy to the breast.
- Trial name
- BOLD (NCT01898533)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
Urethral Analgesia
Effect of Urethral Analgesia on Voiding
The purpose of this study is to evaluate how urethral analgesia impacts voiding efficiency in healthy women. The investigator hypothesizes that anesthetizing the urethral with lidocaine gel will decrease voiding efficiency as…
- Trial name
- NCT02823431
- Testing
- lidocaine gel, Plain aqueous gel
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duke University
Heart Failure
Feasibility of Cardiac Rehabilitation in Patients With Heart Failure at the Moi Teaching and Referral Hospital
This is a study to find out whether cardiac rehabilitation is feasible in Western Kenya. This study will test whether cardiac rehabilitation is feasible by measuring how many participants are able to follow and complete two…
- Trial name
- FCR-HF (NCT02795936)
- Testing
- Cardiac rehabilitation
- Where
- Kenya
- Volunteers
- 100 people
- Sponsor
- Duke University
Back Pain
Spinal Cord Stimulator Implant Study
This study is for patients who have been approved by their doctors and insurance companies to receive spinal cord stimulator implants.
- Trial name
- SCS (NCT00887419)
- Testing
- Coping Skills Training, Education
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Duke University
Smoking
Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)
This project proposes to evaluate the feasibility, acceptability, and efficacy of a mobile intervention to target smoking-cessation and increase physical activity among low-income persons.
- Trial name
- NCT02873754
- Testing
- Cognitive Behavioral Counseling, Mobile Contingency Management, Bupropion
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
Physical Activity
Comparison of Affect-based, Self-selected, and Traditional Exercise Prescriptions
This study will evaluate adherence to four types of walking programs. Participants will be randomized to walking programs that included either (1) affect-based exercise intensity, (2) self-selected (or "choice-based") exercise…
- Trial name
- NCT03047590
- Testing
- Choice-based Exercise Intensity, Positive Affect Focus, Heart rate-based Exercise Intensity
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Duke University