Clinical trials: completed, sponsored by Duke University
Tobacco Cessation
Addressing Tobacco Use Disparities in Rural Older Adults Through an Innovative Mobile Phone Intervention
The purpose of this study is to evaluate the feasibility, acceptability and preliminary efficacy of a Scheduled Gradual Reduction (SGR) intervention via SMS (short message service) text messaging plus SMS Support Messages in…
- Trial name
- NCT02510716
- Testing
- SGR, Support message only
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Port-A-Cath Placement, Octylcyanoacrylate
Comparison of Topical Skin Adhesive to Subcuticular Suture Closure of Implantable Port Incisions
Hypothesis is that incision closure with octylcyanoacrylate is inferior to closure with stitches in Port a Cath patients, who, as a population, are at increased risk for complications.
- Trial name
- NCT02212977
- Testing
- Octylcyanoacrylate, Suture
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Duke University
Physical Activity
Pokemon Go and Physical Activity
The goal of this study to evaluate the association between Pokemon Go and physical activity through a survey among Pokemon Go players.
- Trial name
- Pokemon (NCT02888314)
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Duke University
Dementia
Comparison of Hand Feeding Techniques for Persons With Dementia
The purpose of this study is to test three hand feeding techniques that can be used to provide feeding assistance to persons with dementia - direct hand feeding, hand-over-hand feeding, and hand-under-hand feeding.
- Trial name
- NCT01780402
- Testing
- Hand feeding techniques
- Where
- 11 sites in United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Communication, Obesity
Teen CHAT: Improving Physician Communication With Adolescents About Healthy Weight
The purpose of this study is to teach primary care physicians effective ways to counsel overweight and obese adolescent patients to attain a healthy weight.
- Conditions
- Communication, Obesity, Nutrition, Physical Activity
- Trial name
- TeenCHAT (NCT01040975)
- Testing
- Web-based intervention targeting MD communication; Summary Report
- Where
- United States
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- Duke University
Self-management in Heart Failure
A Randomized Study of the Efficacy of a New Intervention for Medication Adherence in Chronic Illness: Medications, Meaning and Me (The 3-M Study)
Purpose of the study - The purpose of this study is to develop and evaluate the efficacy of a new, theoretically based intervention to improve medication adherence in persons with HF. The hypotheses include: Hypothesis I.
- Trial name
- NCT02258516
- Testing
- CHIME 3-M, attention control
- Volunteers
- 87 people
- Sponsor
- Duke University
Cardiovascular Disease, Hypertension
Evaluating CVD Medication Adherence Program in Low SES
The investigators propose to evaluate the implementation of an efficacious medication adherence program in a group at high risk for CVD.
- Conditions
- Cardiovascular Disease, Hypertension, Diabetes
- Trial name
- CVDMAT (NCT02375737)
- Testing
- m-health
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Other Obstetric Trauma OS
Development of Mental Health Treatment for Obstetric Fistula Patients in Tanzania
The purpose of this study is to determine whether a mental health intervention for obstetric fistula patients in Tanzania improves primary outcomes (depression, PTSD and somatic symptoms) and secondary outcomes (coping, perceived…
- Trial name
- NCT01934075
- Testing
- Mental health treatment
- Where
- Tanzania
- Volunteers
- 60 people
- Sponsor
- Duke University
Coronary Artery Disease, Angina Pectoris
Patient-Reported Preferences Affecting Revascularization Decisions
Selection of a treatment strategy for patients with symptoms due to coronary artery disease requires consideration of patient preferences.
- Trial name
- PREPARED (NCT02272062)
- Testing
- Decision-making tool for coronary artery disease treatment
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Duke University
Pelvic Ring Injury
Pelvic Ring Injury
The purpose of this study is to determine whether displacement on one or all of the standard radiography views done within 6 months and 1 year after a pelvic injury is related to health related quality of life outcomes of…
- Trial name
- NCT01821339
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Breast Cancer
A Pharmacogenomics Study for Breast Cancer Patients Undergoing Adjuvant Chemotherapy With Doxorubicin (A)/Cyclophosphamide ©) and/or Weekly Paclitaxel
RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00131963
- Testing
- cyclophosphamide, doxorubicin, paclitaxel
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Duke University
Fatigue
Measuring Fatigue in Triage: A Pilot Study
The purpose of this study is to determine how the length of a triage shift (i.e. 4 vs., 8 vs., 12 hours) affects fatigue levels among triage nurses in the Emergency Department (ED).
- Trial name
- NCT02519205
- Testing
- Survey
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Presyncope, Syncope
Oral Water Hydration to Prevent Post-Vaccination Presyncope
This is a randomized controlled open-label trial. During the study, adolescents and young adults scheduled to receive at least one intra-muscular (IM) vaccine will receive either oral water hydration in addition to standard care…
- Trial name
- NCT02353390
- Testing
- Oral Water Hydration
- Where
- 2 sites in United States
- Volunteers
- 1,820 people, healthy volunteers welcome
- Sponsor
- Duke University
Night Eating Syndrome
Escitalopram Treatment of Night Eating Syndrome
Night-Eating Syndrome (NES) is an eating disorder characterised by excessive eating at night, sleep disturbance and morning anorexia. This 12-week study examines the effect of escitalopram on symptoms of NES.
- Trial name
- NCT00636649
- Testing
- Escitalopram
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Problems With Emotion Regulation, Psychological Distress
Evaluating a Novel Method of Generalizing Emotion Regulation
The aim of the present project is to develop and evaluate a novel and brief method of generalizing habituation (i.e., calming down after being upset) from an original learning context in the laboratory to other contexts inside…
- Conditions
- Problems With Emotion Regulation, Psychological Distress, Difficulties Coping With Negative Emotions, Anxiety
- Trial name
- EMOGEN (NCT01653548)
- Testing
- Habituation Reminder Training, Habituation Reminder, Habituation
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- Duke University
Diabetes Mellitus, Type 2
Southeastern Diabetes Initiative Clinical Intervention
The purpose of the Southeastern Diabetes Initiative Clinical Intervention is to augment existing standard of care in an effort to (1) improve population level diabetes management, health outcomes and quality of life for diagnosed…
- Trial name
- SEDI (NCT01965639)
- Testing
- Extension of Care
- Where
- 4 sites in United States
- Volunteers
- 648 people
- Sponsor
- Duke University
Osteoarthritis
Patient and Provider Interventions for Managing Osteoarthritis in Primary Care
Osteoarthritis (OA) is one of the most common chronic conditions and a leading cause of pain and disability among adults. Many adults with OA have significant pain and functional limitations, even though they receive some medical…
- Trial name
- PRIMO (NCT01435109)
- Testing
- Patient Behavioral Intervention for OA, Provider Intervention for OA, Combined Patient and Provider Interventions for OA
- Where
- United States
- Volunteers
- 537 people
- Sponsor
- Duke University
Vaginal Cuff Dehiscence, Thermal Injury
Vaginal Cuff Dehiscence and Thermal Injury During TLH
Purpose of this randomized control study is to determine if the mode of electrothermal colpotomy incision affects (1) the degree of thermal injury at the time of laparoscopic hysterectomy or (2) the incidence of clinical…
- Trial name
- NCT02080546
- Testing
- Cut-Coag, V-mode, Valleylab G3000 Electrosurgical Device
- Volunteers
- 120 people
- Sponsor
- Duke University
Hypercapnia, Exercise
Hypercapnia: Cognitive Effects and Monitoring
The investigators will simulate the conditions of a working, helmeted diver by using exercising, "head out" immersed subjects to test the following hypotheses: 1.
- Conditions
- Hypercapnia, Exercise, Nitrogen Narcosis, Diving
- Trial name
- NCT01782625
- Testing
- NO exercise at depth, exercise at depth
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Duke University
Quality Assurance of Malaria Diagnosis
Novel mHealth Platform to Ensure Quality of Community-based Malaria Diagnosis
The investigators propose to implement a new mobile interface that automatically reads and troubleshoots malaria rapid diagnostic test (RDT) cassettes.
- Trial name
- NCT02504593
- Testing
- mHealth platform employing Fionet Deki Readers to ensure quality of community-based malaria diagnosis
- Where
- Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Duke University
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