Clinical trials: sponsored by Ege University
Familial Hypercholesterolemia, Atherosclerosis
Familial Hypercholesterolemia in Turkey (A-HIT2)
A-HIT2, is also designed as a National FH registry. At least 1000 FH patients will be recruited from 30 outpatient clinics representing the 12 Nuts statistical Regions in Turkey proportional to the 2015 Turkey's Population…
- Trial name
- A-HIT2 (NCT03110250)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Ege University
Peripartum Cardiomyopathy
A Registry of Peripartum Cardiomyopathy in Turkey
Peripartum cardiomyopathy (PPCM) is a global disease with significant morbidity and mortality of young women. Its' etiology, epidemiology and treatment is not yet well described.
- Trial name
- NCT03364140
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ege University
Incontinence-associated Dermatitis, Nursing Care
Developing Of A New Incontinence Care Product
The aim of this randomized controlled clinical trial, prospective study is to developing a new incontinece care product for containing the fecal incontinence and to examine the effect of this new product on prevention of perineal…
- Trial name
- NCT02991833
- Testing
- A New Incontinence Care Product, Diaper
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Ege University
Orthodontic Treatment
Flash-free Brackets and Dental Plaque
This study aimed to compare flash-free bracket system with conventional adhesive-coated bracket system in patients with maxillary crowding.
- Trial name
- NCT03187483
- Testing
- orthodontic treatment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ege University
Kidney Transplantation, Anxiety
The Effects of Pre-operative Anxiety on Anesthetic Recovery and Post-operative Pain in Donor Nephrectomy
Kidney transplant is the most effective choice of treatment for patients with end-stage kidney failure in terms of quality of life and longevity. Today, 20-25% of kidney transplantations are implemented with living donors.
- Conditions
- Kidney Transplantation, Anxiety, Pain, Acute, Anesthesia Recovery Period
- Trial name
- NCT03131258
- Testing
- Donor Nephrectomy
- Volunteers
- 48 people
- Sponsor
- Ege University
Lung Diseases
Positions and Peripheral Oxygen Saturation
The subjects were placed consecutively in random order in the five different positions by drawing lots. Oxygen saturation (SaO2) and vital signs (pulse rate, respiratory rate, systolic blood pressure, diastolic blood pressure and…
- Trial name
- NCT03083223
- Testing
- position
- Volunteers
- 109 people
- Sponsor
- Ege University
Tooth Loss, Tooth Mobility
Clinical Follow-up of Direct/Indirect Bridge, Orthodontic and Periodontal Splint by Using Fibre-reinforced Composite
The purpose of this study is to determine whether fibre-reinforced composite resin restorations are effective for single tooth replacement, elimination of tooth mobility following periodontal treatment and as an orthodontic…
- Trial name
- NCT02343796
- Testing
- Fibreglass reinforced composite restoration-everStick, everStick
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ege University
Liver Transplant Recipients
Conversion From Sirolimus to Everolimus in the Maintenance Treatment of Liver Transplant Recipients
This study aims to determine the safety and efficacy of conversion of sirolimus to everolimus in the maintenance treatment of LT recipients. Patients will be monitored every 12 weeks after the switch of treatment for 48 weeks.
- Trial name
- NCT02482974
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ege University
Tooth Loss, Bone Loss
Effect of I-Shape Incısıon Technique on Inter-Implant Papilla: A Prospective Randomized Clinical Trial
Regenerating a predictable inter-implant papilla is the most complex and challenging aspect of implant dentistry. The aim of the study was to compare the efficacy of I shaped incision technique and conventional midcrestal…
- Trial name
- NCT02996370
- Testing
- papilla fill index, crestal bone loss, probing depth
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ege University
Chronic Periodontitis
Burs Versus Curettes in Root Planing.
This study compares the efficacy of diamond burs and Gracey curettes in non-surgical periodontal treatment of chronic periodontitis by clinical, microbiological, biochemical parameters and scanning electron microscopic…
- Trial name
- NCT02875470
- Testing
- Intensiv Perio Set, Gracey curette
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ege University
Tooth Loss, Edentulousness
Soft Tissue Thickness on Submerged and Non Submerged Implants
Changes in the marginal bone level surrounding the implant are the frequently used parameters in assessing the short- and long-term success.
- Trial name
- NCT02842385
- Testing
- Implant
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ege University
White Spot Lesions
Compare the Efficacy of the Remineralization Agents on the White Enamel Lesions
The purpose of this study is to determine whether Fluoride varnish + calcium (Clinpro White Varnish) and polipeptide solution (Curodont Repair) are effective in the treatment of remineralization therapy.
- Trial name
- NCT02341872
- Testing
- Clinpro White Varnish (fluoride + calcium varnish), Curodont Repair
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ege University
Matrix Metalloproteinase Inhibitors, Composite Resins
Effect of Caffeic Acid Phenethyl Ester as a Matrix Metalloproteinase Inhibitor: Randomized Controlled Clinical Trial
Matrix metalloproteinases (MMPs); activated by the application of adhesive systems on dentin cause degradation of the collagen proteins and loss of bond strength in adhesive restorations.
- Trial name
- NCT02744703
- Testing
- total-etch adhesive, CAPE-T, self-etch adhesive
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ege University
Diabetic Foot, Osteomyelitis
Risk Factors for Three Critical Stages of the Diabetic Foot Infections
In this study, it was aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation of the diabetic foot infection in the forward direction without using standard scoring procedures.
- Trial name
- NCT02736253
- Where
- Turkey (Türkiye)
- Volunteers
- 379 people
- Sponsor
- Ege University
Reperfusion Injury
Effect of Pneumoperitoneum on Human Ovary
Laparoscopic surgery has played a pivotal role in all surgical fields in modern medicine. It has some well known advantages over open surgery.
- Trial name
- NCT02731651
- Testing
- open hysterectomy, laparoscopic assisted vaginal hysterectomy
- Volunteers
- 20 people
- Sponsor
- Ege University
Ectopic Pregnancy, Infertility
The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy
The investigators aimed to investigate the effects of salpingectomy and Methotrexate administration on ovarian reserve in ectopic pregnancy.
- Trial name
- NCT02714998
- Testing
- Methotrexate, salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 131 people
- Sponsor
- Ege University
Rectal Ulcer
The Biofeedback Therapy in Solitery Rectal Ulser Patients BIOFEEDBACK THERAPY
Dissynergic defecation causes solitery rectal ulcer. The biofeedback therapy improves dissynegy and heals soliter rectal ulcer.
- Trial name
- NCT02334995
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ege University
Dental Caries
6-year Clinical Evaluation of Glass Ionomer Cements (GIS) With Resin Coating on Posterior Teeth
The aim of this study was to evaluate the long-term clinical performance of two highly viscous encapsulated GICs (EquiaFil and Riva SC) covered with two different coatings (Equia Coat and Fuji Varnish) over 6-year using modified…
- Trial name
- GIS (NCT02616198)
- Testing
- EquiaFil G-coat, EquiaFil Fuji Varnish, Riva SC G-coat
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ege University
Caries
A Clinical Evaluation of a Glass Ionomer Cement (GIC) Based Restorative System Versus Bulk Filled Resin-based Composite
The aim of the present study is to evaluate the clinical performance of EQUİA restoration material in Class II cavities comparing with a resin-based composite / dentin bonding system.
- Trial name
- NCT02479711
- Testing
- composite restoration, glass ionomer cement
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ege University
Class II Lesions
Three-Year Clinical Evaluation of Bonded Posterior Restorations: Amalgam vs Resin Composite
Background: This 3-year clinical trial compared the performance and post-operative sensitivity of a posterior resin composite with that of bonded-amalgam in large sized cavities.
- Trial name
- NCT02393989
- Testing
- posterior restoration
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ege University