Clinical trials: sponsored by Erasmus Medical Center
Bacteremia
Alcohol Locks for the Prevention of Tunneled Catheter-related Infections
In modern-day medicine, the use of central venous catheters has become unavoidable. However, their use does not come without risk.
- Trial name
- NCT00122642
- Testing
- Alcohol-lock
- Where
- Netherlands
- Volunteers
- 440 people
- Sponsor
- Erasmus Medical Center
Bladder Cancer
Cost-Effectiveness in Bladder Cancer
This randomized clinical multicentre trial aims to evaluate the efficacy of microsatellite analysis on voided urine to detect tumour recurrences in the follow-up of patients with superficial urothelialcell carcinoma (UCC).
- Trial name
- NCT00126958
- Testing
- urinary analysis
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
De Novo Renal Transplant Recipient.
Fixed Dose MMF vs Concentration Controlled MMF After Renal Transplantation
Determine the value of a clinically feasible strategy of therapeutic drug monitoring compared with fixed dosing in de novo MMF treated renal transplant recipients with respect to the incidence of treatment failure.
- Trial name
- NCT00166244
- Testing
- Mycophenolate Mofetil
- Where
- 67 sites in Australia, Austria and 17 more
- Volunteers
- 901 people
- Sponsor
- Erasmus Medical Center
Neoplasms, Pain
The Pain Pen for Breakthrough Cancer Pain
The purpose of this study is to see whether injection of hydromorphone through a subcutaneous injection device is more effective in treating breakthrough cancer pain than oral morphine.
- Trial name
- NCT00125801
- Testing
- Subcutaneous hydromorphone delivered by pain pen
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Erasmus Medical Center
Decision Support Systems, Clinical
CholGate - The Effect of Alerting Versus on Demand Computer Based Decision Support on Treatment of Dyslipidaemia by General Practitioners
Indirect evidence show alerting physicians with clinical decision support systems (CDSS) seem to change behaviour more than requiring users to actively initiate the system.
- Trial name
- NCT00348751
- Testing
- CholGate
- Where
- Netherlands
- Sponsor
- Erasmus Medical Center
Tissue Hypoxia, Hyperlactatemia
Early Lactate-Directed Therapy in the Intensive Care Unit (ICU)
Blood lactate levels have long been related to tissue hypoxia, a severe condition in critically ill patients associated with the development of organ system failure and subsequent death.
- Trial name
- NCT00270673
- Testing
- Early lactate-directed therapy
- Where
- 5 sites in Netherlands
- Volunteers
- 350 people
- Sponsor
- Erasmus Medical Center
Quality of Life, Acromegaly
Change in Quality of Life After Addition of Weekly 40 mg Pegvisomant/Placebo in Controlled Acromegalic Patients
Study Synopsis Study Title: Double blind, single centre, cross-over study on the effects of weekly subcutaneous administration of 40 mg pegvisomant or placebo on quality of life and insulin sensitivity in acromegalic patients…
- Trial name
- mec-2005-290 (NCT00642720)
- Testing
- Pegvisomant
- Volunteers
- 20 people
- Sponsor
- Erasmus Medical Center
Distress
Does Massage With or Without Aromatherapy Reduce Infant's Distress?
This study aims to determine the effect of massage with or without aromatherapy on infant´s level of distress
- Trial name
- aromatherapy (NCT00624637)
- Testing
- aromatherapy massage
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Erasmus Medical Center
Diabetes Mellitus, Type 1, Child
Comparison Between Insulin Pump Treatment and Multiple Daily Insulin Injections in Diabetic Type 1 Children
Comparison between insulin pump treatment and multiple daily insulin injections in 38 children with type 1 diabetes4-16 years old. Outcome metabolic control, quality of life, impact of disease and cost effectiveness.
- Trial name
- NCT00462371
- Testing
- Insulin pump (CSII)
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Erasmus Medical Center
Hyperaldosteronism, Hypertension
Diagnostic Properties of Aldosterone-Renin Ratio in Primary Aldosteronism Among Hypertensives.
This study aims to evaluate the diagnostic value of the Aldosterone-Renin Ratio (ARR)as a screening test for primary aldosteronism among hypertensives. The test characteristics will be studied.
- Trial name
- NCT00407784
- Testing
- eplerenone
- Where
- 13 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
Heart Failure, Dyspnea
NT-proBNP in Acute Dyspnea: Effects on Treatment, Hospitalisation and Costs
Diagnostic uncertainty in patients with complaints of shortness of breath presenting to the Emergency Department of a hospital may delay treatment and proper care.
- Trial name
- NCT00410293
- Testing
- NT-proBNP testing
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
Colonic Neoplasms
COlon Cancer Laparoscopic or Open Resection
COLOR trial is a randomized, international, multi center study comparing the outcomes of laparoscopic and conventional resection of colon carcinoma with curative intent.
- Trial name
- NCT00387842
- Testing
- Laparoscopic surgery, Conventional surgery
- Volunteers
- 1,200 people
- Sponsor
- Erasmus Medical Center
Aspergillosis
Inhalation of Liposomal Amphotericin B to Prevent Invasive Aspergillosis
A Phase II/III randomized double-blind study comparing the safety and the efficacy of a weekly administration of 25 mg nebulized AmBisome with nebulized placebo solution to prevent invasive pulmonary aspergillosis in neutropenic…
- Trial name
- NCT00263315
- Testing
- nebulised liposomal amphotericin B
- Where
- 2 sites in Netherlands
- Volunteers
- 320 people
- Sponsor
- Erasmus Medical Center
Esophageal Neoplasms, Microcirculation
Intravenous NTG to Preserve Gastric Microcirculation During Gastric Tube Reconstruction
The aim of the present study was to investigate if NTG, administered intravenously during gastric tube reconstruction, could preserve gastric fundus tissue blood flow and oxygenation and reduce the incidence of postoperative…
- Trial name
- NCT00335010
- Testing
- Nitroglycerin
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Erasmus Medical Center
Strabismus
Bilateral Recession or Unilateral Recession-Resection as Surgery for Infantile Esotropia
Infantile esotropia is corrected in most cases by bilateral recession of the medial rectus muscles (BR) or by unilateral recession of the medial rectus muscle and resection of the lateral rectus muscle (RR).
- Trial name
- NCT00304577
- Testing
- Bilateral recession, Unilateral recession and resection
- Where
- 12 sites in Germany, Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Amblyopia
Electronic Recording of Compliance With Occlusion Therapy for Amblyopia
The purpose of this study was to determine whether compliance with occlusion therapy for amblyopia could be improved and, secondly, if risk factors for non-compliance could be identified.
- Trial name
- NCT00131729
- Testing
- Educational programme
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Postmenopause, Osteoporosis
Effects of Tibolone Treatment on the Endometrium
Tibolone, a tissue-selective compound with a combination of estrogenic, progestogenic and androgenic properties, is used as an alternative for estrogen or estrogen plus progesterone hormone therapy for the treatment of symptoms…
- Trial name
- NCT00294463
- Testing
- Tibolone, Estradiol, Estradiol + Medroxy Progesterone Acetate
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Prostate Cancer, Erectile Dysfunction
A Study to Assess the Efficacy of Tadalafil to Treat Erectile Dysfunction After Radiotherapy of Prostate Cancer
This study has been designed to evaluate the efficacy and safety of a 20-mg dose of tadalafil administered "on demand" to patients with erectile dysfunction (ED) after external-beam radiotherapy (EBRT) of prostate cancer.
- Trial name
- NCT00122499
- Testing
- tadalafil
- Where
- Netherlands
- Sponsor
- Erasmus Medical Center