Clinical trials: sponsored by Fayoum University
Gingivitis, Periodontitis
Galectin Role in Periodontal Disease
This study aimed at exploring the effect of nonsurgical periodontal treatment on galectin 1 and 3 GCF levels in patients having gingivitis, periodontitis stage III compared to periodontally healthy individuals and if galectin-1…
- Trial name
- NCT06038812
- Testing
- GCF sample collection, non-surgical periodontal treatment
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Cardioplegia Solution Adverse Reaction
Modified Del Nido Versus Custodiol Cardioplegia For Myocardial Protection In Cardiac Surgery.
Cardioplegia solutions have been considered as a corner stone for myocardial protection during cardiac surgery with cardiopulmonary bypass and cardiac arrest, it limits the metabolic activity and increases the capacity of the…
- Trial name
- NCT05221294
- Testing
- Modified Del Nido Versus Custodiol Cardioplegia
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Zygomaticomaxillary Complex Fracture
Finite Element and One Point Fixation
A cone beam CT (CBCT) scan of the patient, will be used to create a 3D scanned image of ZMC 3D images will be introduced to finite element (FA)software to evaluate Stresses (MPa) and Life time (cycle) For each model and determine…
- Trial name
- NCT05819372
- Testing
- Zygomaticomaxillary fracture repair
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Fayoum University
Nocturnal Enuresis, Enuresis
Selective Serotonin Reuptake Inhibitors, Fluoxetine Versus the Standard Oral Desmopressin for Management of Mono-symptomatic Nocturnal Enuresis.
To determine whether there is a role for the selective serotonin reuptake inhibitors fluoxetine versus desmopressin in the treatment of nocturnal enuresis in children who have not responded to standard nonpharmacological…
- Conditions
- Nocturnal Enuresis, Enuresis, Enuresis, Nocturnal
- Trial name
- NCT06185361
- Testing
- Fluoxetine 20 MG, Desmopressin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Alveolar Bone Loss
Densah Burs vs. Electrical Mallet in Closed Sinus Lifting.
The aim of the comparative study is to evaluate the density and amount of new bone formed (bone height gain)around dental implant placed simultaneously in posterior maxilla after closed sinus floor elevation using…
- Trial name
- NCT06180187
- Testing
- Electrical mallet, Osseo-densification burs
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Intervention, Cervical
Cervical Epidural Versus Cevical Facet Injection for Patients With Chronic Cervical Pain
After approval of the institutional review board and the Ethics Committee of Al Fayoum University number (D228) , and written informed consent from all patientṣ Pilot study will be done to confirm this sample size .The patients…
- Conditions
- Intervention, Cervical, Epidural, Injection
- Trial name
- D228 (NCT04594876)
- Testing
- Flouroscopic guidance cervical epidural versus cervical facet injection
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Oral Premalignant Lesions as Leukoplakia and Lichen Planus, Oral Cancer
Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant Lesions
Aim: The current study targets linking serum and salivary dipeptidyl peptidase-4 with oral squamous cell carcinoma and comparing it with potentially malignant lesions and control to validate dipeptidyl peptidase-4 as a diagnostic…
- Trial name
- NCT06087042
- Testing
- serum and unstimulated salivary samples
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Diabetes Mellitus Without Complication
Prevent Diabetic Kidney Disease Among Egyptians
Study of the possibility to prevent the development of Diabetic kidney disease in type 2 diabetic patients
- Trial name
- NCT06071208
- Testing
- Gliflozin
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Pain, Ankle Injuries
Erector Spinae Plane Block and Ankle and Foot Surgery
Regional anesthesia is commonly used in orthopedic and surgical procedures in ankle and foot surgery to manage pain. The ultrasound-guided nerve block is a safe and effective regional anesthesia technique that provides effective…
- Trial name
- NCT05708742
- Testing
- Ultrasound, Bupivacaine Hydrochloride, saline solution
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Periodontitis, Adult
GCF miRNA-223 , -214 Levels in Smokers and Nonsmokers Periodontitis Patients
Objective: Periodontitis is a multifactorial disease that affects a wide range of populations. However, its pathogenesis remains unclear. miRNAs are now considered potential diagnostic markers for many inflammatory diseases.
- Trial name
- NCT06064799
- Testing
- miRNA-223 & -214 detection
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Periodontitis, Adult
Fetuin A Association in Periodontal Disease and Diabetes Mellitus
Aim: The aim of the current study was to compare and correlate gingival crevicular fluid (GCF) fetuin-A levels and high sensitivity C-reactive protein (hs-CRP) levels in non-diabetic periodontitis patients and type 2 diabetic…
- Trial name
- NCT06064786
- Testing
- GCF levels of fetuin A and hsCRP evaluation
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Cleft Palate, Growth
Cleft Palate Technique and Maxillary Growth
comparison of the maxillary growth between cleft palate patients that underwent to repair by 2 flap palatoplasty versus Furlow with buccinator technique
- Trial name
- NCT05405738
- Testing
- 2 flap palatoplasty technique, normal group, Furlow with buccinator technique
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Fayoum University
Schizophrenia Spectrum and Other Psychotic Disorders, Periodontal Diseases
Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients
The aim of the present cohort retrospective study is to explore the effect of antipsychotics on periodontal health and the possible effect of antipsychotic-induced hyperprolactinemia as a risk factor for periodontal disease…
- Trial name
- NCT06040944
- Testing
- antipsychotic drugs inducing hyperprolactinemia
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Fayoum University
Potentially Malignant Lesions, Oral Lichen Planus
Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions
The aim of this study is to evaluate salivary expression of lncRNA DQ786243 as a potential marker for diagnosis of oral potentially malignant lesions compared to normal controls and its effect on salivary expression of miRNA146a.
- Conditions
- Potentially Malignant Lesions, Oral Lichen Planus, Leukoplakia, Oral
- Trial name
- NCT05730855
- Testing
- Real-time Polymerase Chain Reaction technique
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Oral Squamous Cell Carcinoma
The Long Non Coding MALAT1 as a Potential Salivary Diagnostic Biomarker in Oral Squamous Cell Carcinoma Through Targeting mi RNA 124
Objective: is to determine the diagnostic accuracy of lncRNA MALAT1 as a potential salivary biomarker of OSCC as well as assessment of the salivary expression level of miRNA 124 which is targeted by MALAT1.
- Trial name
- NCT05708209
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Post Operative Pain
Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve Block
Background: Multimodal analgesia for control of postoperative pain in cardiac surgical patients helps in early recovery and ambulation.
- Trial name
- NCT05897307
- Testing
- Ropivacaine
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Fayoum University Hospital
Mandibular Prognathism
Orthognathic Surgeries and Pharyngeal Airway Space
twenty-four patients with dentoskeletal deformity of class III will be divided equally into two groups and will be subjected to orthognathic surgeries group A; will be treated by mandibular setback surgery while group B will be…
- Trial name
- NCT04629859
- Testing
- mandibular setback and maxillary advancement, mandibular setback
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Fayoum University
Generalized Periodontal Disease, AVDC Stage 3
IL-39 & IL-35 Gingival Crevicular Fluid Levels in Diabetic Patients With Generalized Periodontitis
The sudy was aiming to assess and compare GCF levels of IL-39 \& IL-35 in gingival crevicular fluid and to correlate the relationship between different patient groups before and after non-surgical therapy.
- Trial name
- NCT05880654
- Testing
- Scaling & root planning
- Where
- 2 sites in Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Mechanically Ventilated Patients
The Ratio Of Femoral Vein Diameter To Femoral Artery Diameter With Pulse Pressure Variation As A Diagnostic Tool
In assessing critically ill patients, an accurate assessment of a patient's volume status and whether they will respond to a fluid challenge with an increase in cardiac output is vital.
- Trial name
- NCT05588180
- Testing
- FVD/FAD ratio guided, PPV
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Ketamine-Induced Mood Disorder
The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
Optimal multimodal opioid-sparing analgesic technique is considered as one of the most important Enhanced recovery pathways (ERPs) or enhanced recovery after surgery (ERAS) interventions that mitigate the undesirable effects of…
- Trial name
- NCT05474183
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital