Clinical trials: sponsored by Federico II University
Covid19
OCTA Study: Retinal Vascular Changes in Patients With SARS-CoV-2 Infection
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that have been affected by COVID-19.
- Trial name
- NCT04601012
- Testing
- Optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
Polypoidal Choroidal Vasculopathy
OCTA and Polypoidal Choroidal Vasculopathy
To investigate the structural and vascular features of choroid in patients affected by PCV after Ranibizumab intravitreal injection.
- Trial name
- NCT04714242
- Testing
- Ranibizumab Injection
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
Age Related Macular Degeneration
OCTA and Retinal Angiomatous Proliferation
To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.
- Trial name
- NCT04689789
- Testing
- optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Federico II University
Labor Pain
Effect of Music in Labor in Women Who Underwent Induction of Labor
Women's experience of pain during labor varies greatly, and pain control is a major concern for obstetricians. Several methods have been studied for pain management for women in labor, including drug and non-drug interventions…
- Trial name
- NCT04662424
- Testing
- music in labor
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Federico II University
Neuromuscular Blockade
Effects of Depth of Neuromuscular Block on Surgical Operating Conditions in Gynecologic Laparoscopic Surgery
Comparison of the impact of a deep neuromuscular blockade (TOF count = 0 and posttetanic count [PTC] 1-2) and a moderate neuromuscular blockade (TOF count= 1 - 3) on intraoperative surgical conditions assessed by the surgeon as a…
- Trial name
- NCT03441828
- Testing
- Quality of surgical field conditions, Deep Neuromuscular Block, Moderate Neuromuscular Block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Bariatric Surgery Candidate
OAGB-MGB Conversions for Post-operative Complications
Laparoscopic mini/one anastomosis gastric bypass (MGB/OAGB) is a relatively new bariatric procedure and is gaining ground over the surgical approach for morbid obesity as a safe and effective operation.
- Trial name
- NCT04641715
- Testing
- OAGB-MGB
- Where
- Italy
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Federico II University
Satiety Response, Carbohydrate Metabolism
Low Sodium Neapolitan Pizza Prepared With Seawater: Nutritional Properties, Sensory Characteristics, Metabolic Effects
Seawater is rich in minerals which may help confer good palatability to foods, favouring the use of smaller amounts of salt, a recognized measure of cardiovascular prevention.
- Conditions
- Satiety Response, Carbohydrate Metabolism, Sodium Retention
- Trial name
- NCT04629742
- Testing
- Seawater Pizza, Standard pizza
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federico II University
Cesarean Section
Antepartum Cardiotocography With and Without Computer Analysis in High Risk Pregnancies
Electronic fetal hear rate monitoring (EFM), or cardiotocography (CTG), records changes in fetal heart rate and their temporal relationship to uterine contraction.
- Trial name
- NCT03862976
- Testing
- computerized cardiotocography
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Federico II University
Labor Pain
Trial of Music During Labor and Delivery
The use of music is widely supported in various areas of medicine: first of all in the psychiatric field as in the treatment of autism in children, obtaining surprising results even on Alzheimer's patients, or the unparalleled…
- Trial name
- NCT03779386
- Testing
- music
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federico II University
106 Ruthenium Plaque Brachytherapy, Uveal Melanoma
Uveal Melanoma and Brachytheraphy: Long-term Outcomes.
This study investigated the visual and anatomical outcomes, tumor control, tumor recurrence, distant metastasis and cancer free survival in patients affected by uveal melanoma and undergoing Ru-106 plaque brachytherapy between…
- Trial name
- NCT04577742
- Testing
- 106 Ruthenium plaque brachytherapy
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Federico II University
Scar; Previous Cesarean Section
Cesarean Scar Pregnancy Managed by Dilatation and Evacuation (D&E) Versus Hysteroscopic Surgery
Cesarean scar pregnancy (CSP) is a relative "new" type of ectopic pregnancy where the fertilized egg is implanted in the muscle or fibrous tissue of the scar after a previous cesarean section.
- Trial name
- NCT04205292
- Testing
- hysteroscopic
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Federico II University
Ocular Injury
Study of Retinal Vascular Changes After Ocular Blunt Trauma
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received ocular blunt trauma.
- Trial name
- NCT04546997
- Testing
- Optical Coherence Tomography Angiography
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federico II University
Safety Issues
Tolerability and Modulatory Action of the Butyrate Releaser N-(1-carbamoyl-2-phenyl-ethyl) Butyramide
Accumulating evidence is showing that gut microbiota could play a key role in gastrointestinal tract and immune system development and function. Many beneficial effects elicited by gut microbiota are mediated its metabolites.
- Trial name
- NCT04491266
- Testing
- FBA
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
Erectile Dysfunction Following Radical Prostatectomy
Study of Retinal and Choriocapillary Vascular Changes in Patients Undergoing Tadalafil 20mg for More Than 6 Months
This study evaluates the retinal and choriocapillary vascular features in patients under the effects of Tadalafil 20mg for more than 6 months, using optical coherence tomography angiography.
- Trial name
- NCT04491773
- Testing
- Tadalafil 20 MG
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Federico II University
Autism Spectrum Disorder
Improving Daily Living Skills in People With Autism Spectrum Disorder Through a Personalised Serious Game
This study evaluates the efficacy of a rehabilitation intervention for people with Autism Spectrum Disorder through an individualised serious game developed for improving skills related to a specific daily living activity…
- Trial name
- NCT04295746
- Testing
- Serious Game ShopAut
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Obesity, Childhood, Metabolic Syndrome
Gut Microbiome and Obesity
Pediatric obesity is a risk factor for the onset of obesity in adulthood and is a risk factor for various chronic non-communicable diseases.
- Trial name
- MATOMS (NCT04451148)
- Testing
- Obese with or without metabolic syndromesubjects
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Federico II University
Pituitary Adenoma
Evaluation of Early Retinal Vascular Modifications After Endoscopic Endonasal Pituitary Surgery
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received endoscopic endonasal approach for the removal of an intra-suprasellar pituitary adenoma compressing the…
- Trial name
- NCT04425954
- Testing
- Endoscopic Endonasal Pituitary Surgery
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Federico II University
Change in Flow Mediated Dilation
Effects of FSH on Endothelial Function (FEND)
Purpose of the study will be to evaluate the effects of the s.c. administration of 300 IU of FSH in 16 healthy males. The endothelial function will be evaluated by the measurement with ecographic approach of the flow mediated…
- Trial name
- FEND (NCT04430621)
- Testing
- Follicle Stimulating Hormone
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federico II University
Diabetes, Heart Failure
Clinical and Echocardiographic Management of Patients With Heart Failure and Diabetes: SCODIAC Follow up Study
The study has been carried out to determine diagnostic and therapeutic pathways in a group of HF diabetic patients and to verify whether the use of innovative antidiabetic therapies could modify echocardiographic parameters and…
- Trial name
- NCT04375943
- Testing
- Antidiabetic
- Where
- Italy
- Volunteers
- 406 people
- Sponsor
- Federico II University
Radiation Maculopathy
Evaluation of Retinal and Vascular Features in Radiation Maculopathy After Intravitreal Injections of Ranibizumab
This study evaluates the retinal and vascular features in patients with radiation maculopathy under the effects of Ranibizumab intravitreal injections using optical coherence tomography and optical coherence tomography…
- Trial name
- NCT04377295
- Testing
- Ranibizumab 0.5Mg/0.05Ml Oph Inj
- Volunteers
- 40 people
- Sponsor
- Federico II University