Clinical trials: sponsored by Federico II University
Cardiovascular Risk Factor
Effects of a New Combination of Nutraceuticals (AkP06) Without Monacolin K on Plasma Lipids and Glucose
The study is designed evaluate the effects of a new combination of nutraceuticals (AkP 06) without Monacolin K on lipid and glucose metabolism.
- Trial name
- NCT03340285
- Testing
- AkP06
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Federico II University
Infantile Colic
Evaluation of a Probiotic (Bifidobacterium in the Treatment of Infantile Colic (IC)
Infantile colic (IC) criteria includes all of the following in subjects aged ≤ 4 months: paroxysms of irritability, fussing, or crying that start and stop without obvious cause; episodes lasting 3 or more hours per day and…
- Trial name
- NCT02988791
- Testing
- probiotic (BIfidobacterium, BB-12®)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Federico II University
Heart Failure, Growth Hormone Deficiency
Treatment of GHD Associated With CHF
Aim of the current study is to assess the cardiovascular effects of GH replacement therapy in patients with coexisting GHD and CHF
- Trial name
- NCT03775993
- Testing
- Human growth hormone
- Volunteers
- 64 people
- Sponsor
- Federico II University
Peripheral Artery Disease
Effects of Prolonged DAPT After Lower Extremity Percutaneous Transluminal Angioplasty (PTA) in Patients With LE-PAD
The objective of the present study was to evaluate the prognostic impact of prolonged dual antiplatelet therapy (DAPT) with acetylsalicylic acid plus clopidogrel on the incidence of major adverse cardiovascular events and major…
- Trial name
- LONGDAPTPAD (NCT02798913)
- Testing
- Short DAPT, Long DAPT
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Hypercholesterolemia, Endothelial Dysfunction
Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve
Hypercholesterolemia is considered one of the most important cardiovascular risk factors. Cardiovascular prevention include a class I indication to statins in addition to non-pharmacologic intervention and prevention strategies…
- Trial name
- NUTRENDO (NCT02969070)
- Testing
- LopiGLIK™ therapy, Armolipid Plus® therapy
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federico II University
Safety and Efficacy of Tattooing Substance
Endoscopic Tattooing and Colorectal Cancer
Endoscopic tattooing to facilitate colorectal lesions' identification during laparoscopic surgery is a reliable and widely used technique. India Ink is the standard option for colonic tattoing.
- Trial name
- NCT03637933
- Testing
- endoscopic tattooing
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federico II University
Chronic Heart Failure
The TOSCA Registry: Hormonal and Metabolic Deficiencies in Chronic Heart Failure
The objective of this study is to determine whether the presence of metabolic alteration and anabolic deficiencies in patients with chronic heart failure are able to identify a subset of patients with poor outcome.
- Trial name
- TOSCA (NCT02335801)
- Where
- 17 sites in Italy
- Volunteers
- 650 people
- Sponsor
- Federico II University
Preterm Birth
Prevention of Preterm Birth With a Pessary in Triplet
The incidence of multiple gestations has increased over the past years, mostly because of increased use of assisted reproductive technologies.
- Trial name
- NCT02601443
- Testing
- Cervical Pessary
- Where
- Italy
- Sponsor
- Federico II University
PreTerm Birth
Physical Examination-Indicated Pessary
Cervical insufficiency, previously referred to as cervical incompetence, has classically been defined as painless dilation of the cervix in the absence of contractions or bleeding in the second trimester resulting in recurrent…
- Trial name
- NCT02967445
- Testing
- Arabin Pessary, Cervical cerclage
- Where
- Italy
- Sponsor
- Federico II University
Preterm Birth
Transvaginal Ultrasound Cervical Length Screening in Singleton Pregnancy Without Prior Spontaneous Preterm Birth
Preterm birth (PTB) is a major cause of perinatal morbidity and mortality. Worldwide, about 15 million babies are born too soon every year, causing 1.1 million deaths, as well as short- and long-term disability in countless…
- Trial name
- NCT02928302
- Testing
- TVU CL screening
- Where
- Italy
- Sponsor
- Federico II University
Preterm Birth
Cervical Pessary in Women With Arrested Preterm Labor and Short Cervix
Preterm birth (PTB), defined as birth between 20 and 36 6/7 weeks, is responsible for the majority of the neonatal morbidity and mortality in the United States, and 35% of all U.S. healthcare spending on infants.
- Trial name
- PWK (NCT02849301)
- Testing
- Arabin cervical pessary
- Where
- Italy
- Sponsor
- Federico II University
Preterm Birth
Does Cervical Pessary Prevent Spontaneous Preterm Birth in Twin Pregnancies With Short Cervical Length?
Spontaneous preterm birth (SPTB) remains the number one cause of perinatal mortality in many countries, including the United States. Multiple gestations are at increased risk of SPTB.
- Trial name
- NCT02708264
- Testing
- Cervical pessary
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- Federico II University
Hidradenitis Suppurativa, Mediterranean Diet
Nutritional Status and Hidradenitis Suppurativa (Acne Inversa)
Hidradenitis suppurativa (HS) is a chronic inflammatory, debilitating skin disorder. The exacerbating factors of HS include nutrition and adiposity.
- Conditions
- Hidradenitis Suppurativa, Mediterranean Diet, Body Composition, Vitamin D Deficiency
- Trial name
- NutriHidra (NCT03683238)
- Testing
- Mediterranean Diet
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Federico II University
Hypertension; Nephropathy, Renal Transplant
Effects of Nocturnal Hypertension on Sleep Quality in Renal Transplant Recipients
Nocturnal hypertension (i.e. blood pressure values >120/70 or 10% higher than diurnal values, as measured by ambulatory blood pressure monitoring, ABPM) is particularly frequent in renal transplant recipients (RTR), despite the…
- Conditions
- Hypertension; Nephropathy, Renal Transplant, Sleep Disorder
- Trial name
- NCT03651492
- Testing
- questionnaire administration
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Low FODMAPs Diet in Gastrointestinal Disorders
Recent studies have shown that FODMAPs (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) free diet is efficient in subjects with Irritable Bowel Syndrome (IBS).
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Coeliac Disease
- Trial name
- FODMAPs (NCT03644602)
- Testing
- low FODMAPs diet
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Federico II University
Mediterranean Diet, Neuroendocrine Tumours (NETs)
The Management of Neuroendocrine Tumours: A Nutritional Viewpoint.
Nutritional status in patients with neuroendocrine tumours (NETs), especially of gastroenteropancreatic origin, can be deeply affected by excessive production of gastrointestinal hormones, peptides, and amines, which can lead to…
- Trial name
- NetNutr (NCT03592940)
- Testing
- Mediterranean diet
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Preterm Birth
Pessary in Singleton Gestations With Short Cervix Without Prior Preterm Birth
Spontaneous preterm birth (SPTB) remains the number one cause of perinatal mortality in many countries, including the United States.
- Trial name
- NCT02716909
- Testing
- Cervical pessary
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Common Variable Immunodeficiency
Human IgGs and Endothelial Function in Vivo in Humans
Endothelial dysfunction and insulin resistance play a key role in the onset and development of atherosclerosis, cardiovascular diseases, and diabetes.
- Trial name
- HIGH (NCT03534479)
- Testing
- Polyclonal IgG
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Federico II University
Weight, Body, Smoking
Flavor Test Results in General Population
Dietary choices are influenced by several factors, including physiological, social or genetic factors. Among these, flavor is the most important determinant modulating the preferences versus specific foods.
- Conditions
- Weight, Body, Smoking, Age Problem
- Trial name
- NCT03506074
- Testing
- Flavor test
- Volunteers
- 420 people
- Sponsor
- Federico II University
Vascular Access Complication
Vascular Access in Hematological Patients - PICC Versus CVC
The use of peripherally inserted central catheters (PICCs) represents a major advance for hematological patients, enabling the effective delivery of chemotherapy and/or blood products particularly for prolonged infusions or in…
- Trial name
- NCT02405728
- Testing
- Centrally inserted central catheters (CICCs), Peripherally inserted central catheters (PICCs)
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Federico II University