Clinical trials: sponsored by Galderma R&D
Nasolabial Folds, Wrinkles
Non-comparative Evaluation of Facial Expressions Following Lower Face Correction Using Emervel Classic and Emervel Deep
Study is designed to characterize subject and treating investigator reported outcomes in the early post-treatment period, following bilateral correction of nasolabial folds using Emervel Classic and Emervel Deep. 1.
- Trial name
- NCT02672644
- Testing
- Emervel Classic, Emervel Deep
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Atopic Dermatitis
Efficacy and Safety Study of CD2027 Ointment 3 Microgram Per Gram (mcg/g) Twice Daily Treatment for Adults With at Least Moderate Atopic Dermatitis
This was a multi-center, randomized, double-blind, parallel group study. Efficacy Objectives: To evaluate the efficacy of CD2027 ointment 3 mcg/g applied twice daily over 4 weeks versus its vehicle in adult participants with at…
- Trial name
- NCT00919763
- Testing
- CD2027 Ointment 3 mcg/g, twice daily, Vehicle Ointment, twice daily
- Where
- 14 sites in United States
- Volunteers
- 102 people
- Sponsor
- Galderma R&D
Acne Vulgaris
A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)
The purpose of this study was to demonstrate that daily use of topical trifarotene (CD5789) 50 microgram per gram (mcg/g) cream when used in association with oral antibiotic is safe and effective for the treatment of severe AV.
- Trial name
- DUAL (NCT04451330)
- Testing
- Trifarotene cream, Doxycycline hyclate, Trifarotene Vehicle
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 202 people
- Sponsor
- Galderma R&D
Actinic Keratoses
Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream (CD06809-41) Versus Vehicle Cream for Actinic Keratosis of the Face
A Randomized, Double-Blind, Vehicle-Controlled, Multicenter Study to Assess the Efficacy and Safety of Methyl aminolevulinate hydrochloride (MAL) 16.8% cream (CD06809-41) versus vehicle cream in the treatment of thin and…
- Trial name
- NCT04085367
- Testing
- MAL 16.8% cream, MAL Vehicle Cream
- Where
- 60 sites in United States, Puerto Rico
- Volunteers
- 557 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Participant Reported Outcomes With Use of Trifarotene 50 μg/g Cream in the Treatment of Moderate Facial and Truncal Acne Vulgaris
Participant Reported Outcomes with use of Trifarotene 50 μg/g Cream in participants with Moderate Facial and Truncal Acne Vulgaris
- Trial name
- NCT03915860
- Testing
- Trifarotene
- Where
- 9 sites in United States
- Volunteers
- 47 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Dose Range Study of CD5789 in Acne Vulgaris
To assess the efficacy and safety of different concentrations of CD5789 cream in participants with acne vulgaris for the purpose of dose identification.
- Trial name
- NCT01616654
- Testing
- CD5789 25 µg/g cream, CD5789 50 µg/g cream, CD5789 100 µg/g cream
- Where
- 24 sites in United States
- Volunteers
- 304 people
- Sponsor
- Galderma R&D
Xerosis Cutis
Comparison Dry Foot Skin Between Diabetic and Non-diabetic Subjects and the Effects of Two Cosmetic Foot Care Products
The overall aims of this study are to compare the structure and function of dry to very dry and cracked foot skin between diabetic and nondiabetic subjects and to evaluate the effects of two cosmetic leave-on products on dry and…
- Trial name
- NCT05046015
- Testing
- 10% Urea foot lotion, 10% Urea foot ointment
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Healthy Volunteers
Anesthetic Effect Duration Assessment
The purpose of this study is to evaluate the duration of anesthetic effect produced , Lidocaine7% + Tetracaine 7% cream when applied with 2 different application times on the face and thigh.
- Trial name
- NCT01545765
- Testing
- Lidocaine 7% + Tetracaine 7% cream
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Rosacea, Erythema
Patient-Reported Outcome Of Facial Erythema (PROOF)
The purpose of the study is to evaluate the patient-reported outcomes (feedbacks of patients)of a new drug for the treatment of erythema of rosacea (central facial redness).
- Trial name
- PROOF (NCT01885000)
- Testing
- Brimonidine tartrate was applied cutaneously once daily for 8 days., Brimonidine tartrate vehicle was applied cutaneously once daily for 8 days.
- Where
- 14 sites in Germany, Sweden and 1 more
- Volunteers
- 92 people
- Sponsor
- Galderma R&D
Rosacea
Mirvaso® Utilisation and Patient Satisfaction Evaluation (MUSE)
The aim of the study is to evaluate the level of satisfaction among patients to whom Mirvaso® / Onreltea TM (trade mark) is prescribed.
- Trial name
- MUSE (NCT02637232)
- Testing
- Mirvaso® / Onreltea TM
- Where
- Canada
- Volunteers
- 301 people
- Sponsor
- Galderma R&D
Actinic Keratosis
Gene Expression in Renal Transplant Patients With Field Actinic Keratosis Undergoing Metvix® Photodynamic Therapy (PDT)
The aim of this study is to determine possible molecular changes on large scale gene expression profiling after treatment with Metvix photodynamic therapy (PDT) of actinic keratoses (AK) and cancerised field in renal transplant…
- Trial name
- NCT01000636
- Testing
- Metvix PDT
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- Galderma R&D
Cutaneous T Cell Lymphoma
A Safety, Efficacy and Pharmacokinetics Study of CD11301 for the Treatment of Cutaneous T-Cell Lymphoma (CTCL)
To assess the efficacy, safety and pharmacokinetics in participants treated with CD11301 gel vs. placebo for early stage CTCL (IA, IB, or IIA).
- Trial name
- CTCL (NCT03292406)
- Testing
- CD11301 0.03%, CD11301 0.06%
- Where
- 21 sites in United States, France and 1 more
- Volunteers
- 86 people
- Sponsor
- Galderma R&D
Foot Dermatoses
Treatment of Onychomycosis With Loceryl (Amorolfine) Nail Lacquer 5% Versus Ciclopirox Nail Lacquer
The main objective of this study is to compare subject's compliance and satisfaction for two modes of treatment of toenails infection (Onychomycosis) with Loceryl Nail Lacquer (Loceryl NL) and Ciclopirox Nail Lacquer (Ciclopirox…
- Trial name
- LOOP (NCT02679911)
- Testing
- Loceryl NL, Ciclopirox NL
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Galderma R&D
Rosacea
Oracea Soolantra Association in Participants With Severe Rosacea
The main objective of this study is to evaluate the efficacy of Ivermectin 1% topical cream associated with Doxycycline 40 mg Modified release (MR) capsules versus Ivermectin 1% topical cream associated with Placebo in the…
- Trial name
- ANSWER (NCT03075891)
- Testing
- Ivermectin 1% cream, Doxycycline 40 mg MR (30 mg Immediate Release & 10 mg Delayed Release beads) capsules
- Where
- 21 sites in United States, Canada and 1 more
- Volunteers
- 273 people
- Sponsor
- Galderma R&D
Facial Wrinkles
Global Management of Facial Rejuvenation With a New Range of Hyaluronic Acid Dermal Fillers
The aim of this study is to assess performance and tolerance as well as investigator and subject satisfaction linked to the global management of facial rejuvenation with a new range of hyaluronic acid dermal fillers.
- Trial name
- FRESH (NCT01151436)
- Testing
- hyaluronic acid dermal fillers
- Where
- 5 sites in France, Germany
- Volunteers
- 77 people
- Sponsor
- Galderma R&D
Rosacea
Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
The purpose of this vehicle controlled study is to evaluate the efficacy and safety of CD07805/47 gel 0.5% applied topically once daily (QD) for 4 weeks, and CD07805/47 gel 0.18% applied topically once daily (QD) or twice daily…
- Trial name
- NCT01174030
- Testing
- CD07805/47 Gel, Vehicle Gel
- Where
- 20 sites in United States
- Volunteers
- 269 people
- Sponsor
- Galderma R&D
Healthy Subjects, Male or Female, of 18-60 Years Old, With Phototype I, II or III, Not Pre-treated/Pre-protected Skin
Performance of Different Application Regimens of ACTINICA® on Protection From UVR-induced Erythema After One Day of Sun Exposure in Fair-skinned Healthy Subjects.
Study objective To assess the performance of different application regimens of Actinica® on protection from UV rays-induced erythema throughout 1 day of sun exposure in fair-skinned healthy subjects (phototype I to III).
- Trial name
- NCT02251756
- Testing
- Actinica, 0.8 mg/cm2, 1 application, Actinica, 0.8 mg/cm2, 2 applications, Actinica, 2 mg/cm2, 1 application
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Rosacea
Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
A long-term, open-label, non-comparative safety and efficacy study of CD07805/47 gel 0.5% once daily in subjects with moderate to severe facial erythema associated with rosacea.
- Trial name
- NCT01318733
- Testing
- CD07805/47 gel 0.5%
- Where
- 27 sites in United States
- Volunteers
- 449 people
- Sponsor
- Galderma R&D
Acne Scars
Adapalene Gel 0.3% in the Treatment of Atrophic Acne Scars
The purpose of this study is to assess the efficacy and safety of Adapalene Gel 0.3% in the treatment of atrophic acne scars.
- Trial name
- NCT01213199
- Testing
- Adapalene
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Galderma R&D
Actinic Keratoses
Intra-individual Comparison of Efficacy and Safety of Metvix® Natural Daylight Photodynamic Therapy Versus Conventional Metvix® Photodynamic Therapy in Subject With Mild Actinic Keratoses
The main objective of this study is to compare efficacy and safety of Metvix® natural daylight photodynamic therapy with those of Metvix® conventional photodynamic therapy with Aktilite™ lamp in subjects with mild actinic…
- Trial name
- CoMet (NCT01475071)
- Testing
- Metvix and natural daylight PDT, Metvix and conventional PDT
- Where
- 6 sites in Australia
- Volunteers
- 100 people
- Sponsor
- Galderma R&D