Clinical trials: sponsored by Galderma R&D
Erythematotelangiectatic Rosacea
Dose-Finding Study of CD07805/47 Topical Gel in Subjects With Erythematotelangiectatic Rosacea
This is a randomized, double-blind, parallel-group, vehicle-controlled, dose-finding study to investigate the pharmacodynamics and the safety of three dosages of CD07805/47 topical gel (0.07%, 0.18%, and 0.50%), after a single…
- Trial name
- NCT00989014
- Testing
- CD07805/47
- Where
- 5 sites in United States
- Volunteers
- 122 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Placebo Controlled Efficacy and Safety Study of CD2475/101 40 mg Tablets vs. Placebo and Doxycycline 100 mg Capsules Once Daily in the Treatment of Inflammatory Lesions of Acne Vulgaris
The primary objectives of the study is to show CD2475/101 40mg tablets taken once a day for 16 weeks is superior to the placebo in Change from baseline to Week 16(Last Observation Carry Forward, Intent To Treat) in inflammatory…
- Trial name
- NCT01320033
- Testing
- CD2475/101 40 mg, Doxycycline 100 mg
- Where
- 31 sites in United States
- Volunteers
- 662 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Benzac 5% Gel in Combination With Cosmetic Products in Acne Vulgaris
The aim of this study is to evaluate a complete acne regimen consisting of a medication (Benzaknen® 5% Gel), and 2 cosmetic products Dermotivin® Soft Liquid soap and Cetaphil® Dermacontrol Moisturizer SPF30 in patients with acne.
- Trial name
- Benzac (NCT02589405)
- Testing
- Benzoyl Peroxide, Dermotivin® Soft Liquid cleanser, Cetaphil® Dermacontrol Moisturizer SPF30
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Galderma R&D
Plaque Psoriasis
PK and PD Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis
The purpose of this study is to determine if the calcitriol absorption in pediatric subjects is comparable to that in adults and adolescents, with no significant impact on calcium/phosphorus metabolism.
- Trial name
- NCT01766440
- Testing
- Calcitriol 3 mcg/g ointment
- Where
- 8 sites in United States
- Volunteers
- 18 people
- Sponsor
- Galderma R&D
Plaque-type Psoriasis
Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of CD 2027 Spray in Adults With Plaque-type Psoriasis
This is a multicenter, open-label study to assess systemic plasma levels of calcitriol, calcium homeostasis and safety in adults with plaque-type psoriasis under conditions of maximized use of CD 2027 3µg/g oily spray twice daily…
- Trial name
- NCT00763503
- Testing
- CD 2027
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- Galderma R&D
Papulopustular Rosacea
Phase 3 Papulopustular Rosacea Study
The purpose of this study is to demonstrate that CD5024 1% cream is more effective than its vehicle when applied once daily, at bed time, during a 12 week period in subjects with Papulopustular Rosacea (PPR) and continues to be…
- Trial name
- NCT01494467
- Testing
- CD5024, Azelaic acid 15% Gel
- Where
- 50 sites in United States, Canada
- Volunteers
- 688 people
- Sponsor
- Galderma R&D
Severe Acne Vulgaris
Adapalene-BPO Gel Associated With Doxycycline Hyclate 100 mg in the Treatment of Severe Acne Vulgaris
The purpose of this study is to demonstrate the efficacy of Adapalene 0.1% / Benzoyl Peroxide (quoted as BPO) 2.5% Gel associated with Doxycycline Hyclate 100 mg Tablets compared to Adapalene 0.1% /Benzoyl Peroxide 2.5% Vehicle…
- Trial name
- ACCESS I (NCT00688064)
- Testing
- Adapalene BPO Gel associated with Doxycyline Hyclate, Vehicle Gel associated with Doxycycline Hyclate
- Where
- 34 sites in United States, Canada and 1 more
- Volunteers
- 459 people
- Sponsor
- Galderma R&D
Healthy Skin
Adjunctive Usage of a Moisturizing Lotion (Cetaphil® Moisturizing Lotion) to Limit the Skin Irritation Linked to the Set-Up of a Treatment by Topical Retinoid (Differin® Gel 0,1%) in Healthy Subjects of Chinese Origins
This is a single-center study, randomized, Investigator/Evaluator-blinded bilateral (split-face) comparison. The objective: To assess the benefit of the concomitant use of a Moisturizing Lotion in reducing the skin irritation…
- Trial name
- NCT00971282
- Testing
- adapalen 0.1%, Cetaphil®
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Blepharitis, Meibomianitis
Treatment of Patients With Blepharitis and Facial Rosacea
To determine the safety and efficacy of sub-antimicrobial dose COL-101 in the treatment of patients who have both blepharitis and facial rosacea
- Conditions
- Blepharitis, Meibomianitis, Dry Eye
- Trial name
- NCT00560703
- Testing
- COL-101 (doxycycline, USP) capsules
- Where
- 8 sites in United States
- Volunteers
- 70 people
- Sponsor
- Galderma R&D
Metatarsalgia
Volume Restoration of Plantar Pad With a Hyaluronic Acid Dermal Filler in Metatarsalgia
Aim of this study is to evaluate the decrease of plantar pain of forefeet due to restoration of plantar pad tissue density and of cushioning function with an hyaluronic acid dermal filler as mechanical-supplementation in subjects…
- Trial name
- ELFE (NCT02369380)
- Testing
- Hyaluronic acid
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Galderma R&D
Wrinkles
Comparison of Two Botulinum Toxins Type A on Forehead Wrinkles
Single-centre, controlled, randomized, evaluator-blinded, bilateral (split-face) comparison study in subjects with moderate to severe forehead wrinkles.
- Trial name
- NCT01014871
- Testing
- Botulinum Toxin Type A - Azzalure, Botulinum Toxin Type A - Vistabel
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Galderma R&D
Scalp Seborrheic Dermatitis
Clobetasol Propionate 0.05% Shampoo in Association With Antifungal Shampoo in Scalp Seborrheic Dermatitis
The objective is to assess different treatment regimens with Clobetasol propionate shampoo 0.05% in the treatment of scalp Seborrheic Dermatitis.
- Trial name
- Escape (NCT00862654)
- Where
- 18 sites in Belgium, France and 3 more
- Volunteers
- 326 people
- Sponsor
- Galderma R&D
Acne
Comparison of Four Different Regimens of Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel in Acne Vulgaris
The purpose of this study is to compare the tolerability of 3 treatment regimens containing Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel with that of Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel standard daily overnight application…
- Trial name
- FREE (NCT00883233)
- Testing
- Adapalene BPO Gel standard daily overnight application, Adapalene-BPO 3-hour daily application before bedtime, Adapalene-BPO Gel every other day application
- Where
- 2 sites in Canada
- Volunteers
- 123 people
- Sponsor
- Galderma R&D
Acne
Efficacy & Safety Comparison of Epiduo With Doxycycline Versus Vehicle With Isotretinoin in the Treatment of Severe Acne
Non-inferiority, randomized, controlled, multi-center, investigator-blind, parallel-group comparison study in subjects with severe acne vulgaris on the face.
- Trial name
- POWER (NCT01474590)
- Testing
- Epiduo/Tactuo, vehicle gel, doxycycline 200mg
- Where
- 25 sites in Canada
- Volunteers
- 266 people
- Sponsor
- Galderma R&D
Acne
Patient Education in Adherence on Acne (PEAce)
This is a multi-center, randomised and controlled study in subjects with acne vulgaris. The main objective of this study is to evaluate the effect of a supplementary patient education intervention (in addition to the…
- Trial name
- NCT02307266
- Testing
- Standard of care + supplementary education, Standard of care + additional visits, Standard of care
- Where
- 10 sites in United Kingdom
- Volunteers
- 97 people
- Sponsor
- Galderma R&D
Psoriasis Vulgaris
Long Term Safety and Efficacy Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis
The objective of this study is to evaluate the safety and efficacy of up to 26 weeks of treatment with calcitriol 3 mcg/g ointment when used twice daily, without occlusion, to treat pediatric subjects (2 to 16 years and 11 months…
- Trial name
- NCT02125279
- Testing
- Calcitriol
- Where
- 16 sites in United States, Belgium and 3 more
- Volunteers
- 54 people
- Sponsor
- Galderma R&D
Plaque Psoriasis
Plaque Psoriasis Study in Pediatric Subjects
The purpose of this study is to compare the safety, efficacy and calcium metabolism of up to 8 weeks of treatment with calcitriol 3 mcg/g ointment versus its vehicle, when used twice daily, without occlusion, to treat children…
- Trial name
- NCT02186665
- Testing
- calcitriol ointment
- Where
- 34 sites in United States, Belgium and 5 more
- Volunteers
- 19 people
- Sponsor
- Galderma R&D
Aging
Subjects' Satisfaction on Pan Facial Aesthetic Enhancement After Treatment With Azzalure® and the Restylane® Range
The aim of this study is to assess subjects' satisfaction linked to the pan facial management of rejuvenation with injections of Azzalure® and Restylane® fillers. This will be an open, multi-centre study.
- Trial name
- FIRST (NCT01529203)
- Testing
- Botulinum Toxin Type A (Azzalure), Restylane ranges
- Where
- 5 sites in France, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Comparison of Epiduo Associated With Lymecycline Versus Epiduo Vehicle Associated With Lymecycline in Acne Vulgaris
Randomized, controlled, multi-center, double-blind, parallel-group comparison study in Subjects with moderate to severe acne vulgaris on the face.
- Trial name
- TEAM (NCT01014689)
- Testing
- Adapalene/ BPO gel with Lymecycline capsules, Adapalene/ BPO vehicle gel with Lymecycline capsules
- Where
- 28 sites in Australia, Belgium and 7 more
- Volunteers
- 378 people
- Sponsor
- Galderma R&D
Melasma
Comparison of Two Tri-Luma® Maintenance Regimens in the Treatment of Melasma
Melasma is an acquired, symmetric, irregular hypermelanosis on sun-exposed areas of the face, commonly seen in Latin American women. It is a very frequent disease, although its true incidence is unknown.
- Trial name
- CLARA (NCT00500162)
- Testing
- Tri-Luma Maintenance regimen
- Where
- 2 sites in Brazil, Mexico
- Volunteers
- 340 people
- Sponsor
- Galderma R&D